Pesticide Residues in Food - 1997. Report. (FAO Plant Production and Protection Paper - 145)

Report of the Joint Meeting of the
FAO Panel of Experts on Pesticide Residues
in Food and the Environment
and the WHO Core Assessment Group on Pesticide Residues
Lyons, France
22 September - 1 October 1997

WORLD HEALTH ORGANIZATION

Food and Agriculture Organization of the United Nations
Rome, 1998

Monographs containing summaries or residue data and toxicological data considered at the 1997 JMPR, together with recommendations, are available upon request from FAO or WHO under the title:

Pesticide residues in food -1997
Evaluations 1997
Part I: Residues
FAO Plant Production and Protection Paper
and Part II: Toxicology
WHO

The designations employed and the presentation of material in this publication do not imply the expression of any opinion whatsoever on the part of the Food and Agriculture Organization of the United Nations or the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries.

This report contains the collective views of two international groups of experts and does not necessarily represent the decisions or the stated policy of the Food and Agriculture Organization of the United Nations or of the World Health Organization.

INTERNATIONAL PROGRAMME ON CHEMICAL SAFETY
The preparatory work for the toxicological evaluations of pesticide residues carried out by the WHO Expert Group on Pesticide Residues for consideration by the FAO/WHO Joint Meeting on Pesticide Residues in Food and the Environment is actively supported by the International Programme on Chemical Safety (IPCS).
IPCS is a joint venture of the United Nations Environment Programme, the International Labour Organisation and the World Health Organization. One of the main objectives of IPCS is to carry out and disseminate evaluations of the effects of chemicals on human health and the quality of the environment.

M-84
ISBN 92-5-104116-4

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying or otherwise, without the prior permission of the copyright owner. Applications for such permission, with a statement of the purpose and extent of the reproduction, should be addressed to the Director, Information Division, Food and Agriculture Organization of the United Nations, Viale delle Terme di Caracalla, 00100 Rome, Italy.

©FAO and WHO 1998

This electronic document has been scanned using optical character recognition (OCR) software and careful manual recorrection. Even if the quality of digitalisation is high, the FAO declines all responsibility for any discrepancies that may exist between the present document and its original printed version.

PARTICIPANTS

ABBREVIATIONS WHICH MAY BE USED

USE OF JMPR REPORTS AND EVALUATIONS BY REGISTRATION AUTHORITIES

1. INTRODUCTION

2. GENERAL CONSIDERATIONS

2.1. FAO Manual on the submission and evaluation of pesticide residues data for the estimation of maximum residue levels in food and feed

2.2 Submission of information for consideration by the FAO Panel

2.3 MRLS for pesticides for which JMPR estimates of dietary intake exceed the ADI

2.4 The estimation of maximum residue and STMR levels for products of animal origin when residues are transferred from feed items

2.5 Extrapolation of residue data to minor crops

2.6 Calculation of dietary intake of pesticide residues

3. SPECIFIC PROBLEMS

3.1 Harmonisation of recommendations from the JMPR and JECFA for MRLs for pesticides with both agricultural and veterinary uses

3.2 Nature of fat samples in studies on fat-soluble compounds

3.3 Assessment of chronic dietary risk of dithiocarbamate pesticides

4. EVALUATION OF DATA FOR ACCEPTABLE DAILY INTAKE FOR HUMANS, MAXIMUM RESIDUE LEVELS, AND STMR LEVELS

4.1 Abamectin (T, R)

4.2 Amitrole (T)

4.3 Bifenthrin (R)

4.4 Captan (R)

4.5 Carbofuran (R)**

4.6 Carbosulfan (R)**

4.7 Chlormequat (T)

4.8 Chlorothalonil (R)

4.9 Clethodim (R)

4.10 2,4-D and its salts and esters (E)

4.11 Ethephon (T)

4.12 Fenamiphos (T)**

4.13 Fenbuconazole (T,R)*

4.14 Fenthion (T)

4.15 Fipronil (T)*

4.16 Folpet (R)

4.17 Glyphosate (T,R)

4.18 Guazatine (T,R)**

4.19 Lindane (gamma-HCH) (T)

4.20 Malathion (T)**

4.21 Methamidophos (R)

4.22 Methidathion (T)

4.23 Mevinphos (E,R)**

4.24 Myclobutanil (R)

4.25 Parathion (R)

4.26 Phosalone (T)

4.27 Phosmet (R)**

4.28 Tebuconazole (R)

4.29 Tebufenozide (R)

4.30 Thiabendazole (R)**

4.31 Triforine (T)**

5. RECOMENDATIONS

6. FUTURE WORK

6.1 1998 Meeting (tentative)

6.2 1999 Meeting (tentative)

7. REFERENCES

ANNEX I - ADIs, acute RfDs, recommended MRLs, STMRs, GLs

ANNEX II - Index of reports and evaluations

ANNEX III - Intake predictions

FAO technical papers