Newcastle disease is a severe clinical manifestation of infection with Newcastle disease virus. The disease is seen mainly in chickens.
In chickens, Newcastle disease often causes high or total mortality in a flock. Chickens may die without showing any clinical signs of infection.
Common clinical signs of acute infection
Greenish blood-stained diarrhoea
Torticollis (abnormal position and twisting of the neck, limited movements of the head)
Loss of appetite
Common post-mortem findings
Hyperaemia and congestion in respiratory tract
Serous or catarrhal exudates in larynx and trachea
Thickened air sacs, may contain yellow exudates
Haemorrhagic lesions in digestive tract: with some necrosis especially in proventriculus
Haemorrhages in the intestinal lymphoid nodules and caecal tonsils
Presumptive: Based on clinical signs and post mortem findings
Unequivocal: Isolation of virulent Newcastle disease virus from samples for example blood, bone, spleen, lungs
Sero-diagnosis: Monitoring of antibody levels in acute and convalescent serum samples.