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Abstract 488

A note on the removal of growth depressant factor in neem (Azadirachta indica) seed cake.

Vijjan,-VK

Division of Pharmacology and Toxicology, Indian Veterinary Research Inst., Izatnagar 243 122, India.

Journal-of-Veterinary-Physiology-and-Allied-Sciences. 1983, 2: 1, 25-28; 10 ref.

Attempts were made to extract the toxic, growth-depressant component in Azadirachta indica oilmeal by treatment with petroleum ether (40-60øC) or cold 95% alcohol, or boiling water, or successive treatments with alcohol and water. Rats were given diets which included 10% A. indica oilmeal, untreated or treated as above. From study of growth of the rats, it was concluded that a previously discovered, growth-depressant factor in the oilmeal is water soluble and can be removed more or less completely by extraction with water.

This abstract relates to the following species:

Azadirachta indica