Edición en línea: "Compendio de especificaciones para aditivos alimentarios"


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versión imprimible

Medicamento veterinario Cloramfenicol
La clase funcional Antimicrobial agent
Ultima evaluación 2004
Reunión de JECFA 62
IDA No ADI
Estatus de IDA None
Monografías de residuos
41-1
41-6
Definición del residuo  
Límites máximos para residuos (LMR) recomendados
Otras observaciones The Committee concluded that it is not appropriate to establish an ADI for chloramphenicol.
TRS 925 
El resumen de la evaluación The Committee was unable to establish an ADI for chloramphenicol both because of the lack of the information needed to assess its carcinogenicity and effects on reproduction, and because the compound was genotoxic in a number of in vitro and in vivo test systems.
The Committee was unable to assign MRLs for chloramphenicol primarily because no ADI was allocated. In addition, insufficient information was available to identify a suitable marker residue, particularly in cattle and pigs, for which the radio-depletion studies were considered inadequate.
TRS 851