At its 44th meeting JECFA considered a new approach to the safety evaluation of flavouring agents. This approach incorporates a series of criteria whose use enables the evaluation of a large number of these agents in a consistent and timely manner. At the current meeting of the Committee specifications of identity and purity were prepared or revised for 138 flavouring agents.
Information on specifications for flavouring agents is given on the following tables under the following headings, most of which are self-explanatory:
Name; Chemical name (Systematic name); Synonyms; Flavour and Extract Manufacturers' Association of the United States (FEMA) No; FLAVIS (FL) No; Chemical Abstract Service Registry (CAS) No; Molecular weight; Chemical formula; Physical form/odour; Solubility; Solubility in ethanol, Boiling point (for information only); Identification test (ID); Assay min% (Gas chromatographic (GC) assay of flavouring agents); Acid value max; Refractive index (at 20º, if not otherwise stated); Specific gravity (at 25º, if not otherwise stated)
The field called "Other requirements" contains three types of entry:
Items in normal type are additional requirements, such as further purity criteria or other tests
Items contained in square brackets are provided for information, for example the typical isomer composition of the flavouring agent. These are not considered to be requirements.
Substances listed after "SC:" are secondary constituents which have been taken into account in the safety evaluation of the named flavouring agent. If the commercial product contains less than 95% of the named compound, it is a requirement that the major part of the product (i.e. not less than 95%) is accounted for by the sum of the named compound and one or more of the secondary constituents.
The field called "JECFA" contains the number of the meeting at which the specifications were prepared and the status of the specification. R means "specifications revised", S means "existing specifications maintained", S,T means "existing tentative specifications maintained, (further information required)", N means "new specifications", N,T means "new tentative specifications, (further information required)", and N,C means "new specifications for a flavouring agent with a conditional safety evaluation". In Section A of this document further information on the conditional safety evaluation and its implications are given.
The last column indicates the data (information) required for the tentative specifications. Abbreviations for "data required" are as follows: A=assay minimum, A(e)=equivalence factor for assay, A(m)=details of assay method, BP=boiling point, ID=identity test, Low assay=quantitative information on by-products, RI=refractive index, SG=specific gravity. A(e) is an equivalence factor to convert an assay obtained by aldehyde/ketone determination, ester determination, total alcohols determination, or titration determination to the % value which would be obtained if GC had been used for the assay (FNP 5).
The infrared and other spectra, used for identification and comparison purposes, are provided from page 71 onwards (copies for certain spectra may be obtained from the FAO Joint Secretariat in Rome or from FEMA, Suite 925, 1620 I Street, N.W., Washington DC, USA).
A comprehensive index listing all names, chemical names, and synonyms is added on page 90.
| Note on spectra: only spectra which were submitted to the 65th meeting are reproduced in this volume. The reader is referred to previous Addenda for copies of spectra of revised specifications. |
| No | Name chemical name/synonyms | FEMA/FL/CAS numbers | Formula M.W. | Physical form/odour | Solubility/solubility in ethanol | B.P. (°C) | ID test/assay min | A.V. | Ref. index/Sp. gravity | Other requirements | JECFA | Data required |
| 631.2 | 3-Methyl-2-oxobutanoic acid, sodium salt | 3869 | C5 H7 O3 Na | - | - | n/a | NMR | - | n/a | Assay by hplc using an ion exchange column | 65th/R,T | A(m) |
| 632.2 | 3-Methyl-2-oxopentanoic acid, sodium salt Sodium 3-methyl-2-oxovalerate Valeric acid, 3-methyl-2-oxo-, sodium salt | 3870 | C6 H9 O3 Na | - | - | n/a | NMR | - | n/a | Assay by hplc using an ion exchange column | 65th/R,T | A(m) |
| 633.2 | 4-Methyl-2-oxopentanoic acid, sodium salt Sodium 4-methyl-2-oxovalerate Valeric acid, 4-methyl-2-oxo, sodium salt; Sodium 4-methyl-2-ketopentanoate; Sodium 4-methyl-2-oxopentanoate | 3871 | C6 H9 O3 Na | - | - | n/a | NMR | - | n/a | Assay by hplc using an ion exchange column | 65th/R,T | A(m) |
| 1479 | Sodium 2-oxo-3-phenylpropionate Sodium 2-oxo-3-phenylpropionate Sodium 3-phenylpyruvate | 3892 | C9 H7 O3 Na | - | - | n/a | NMR | - | n/a | Assay by hplc | 65th/R,T | A(m) |
| 1480 | Maltol 3-Hydroxy-2-methyl-4-pyrone 2-Methylpyromeconic acid; 3-Hydroxy-2-methyl-4-pyrone; Larixinic acid; INS No.636 | 2656 | C6 H6 O3 | White crystalline powder | Very slightly soluble in water, ether | - | NMR | - | - | mp: 159-162°; Complies with purity criteria for Maltol in FNP52 | 65th/N | |
| 148 | Ethyl maltol 2-Ethyl-3-hydroxy-4-pyrone 2-Ethyl-3-hydroxy-4-pyrone; 2-Ethyl-3-hydroxy-4H-pyran-4-one; 2-Ethylpyromeconic acid;; INS No.637 | 3487 | C7 H8 O3 | White crystalline powder | Soluble in water, propylene glycol; Slightly soluble in glycerine | - | NMR | - | - | mp: 89-93°; Complies with purity criteria for Ethyl maltol in FNP52 | 65th/N | |
| 1482 | Maltyl isobutyrate 2-Methyl-4H-pyran-4-one-3-yl 2-methylpropanoate 2-Methyl-4-oxo-4H-pyran-3-yl isobutyrate; Maltyl 2-methylpropanoate; 2-Methyl-4-pyron-3-yl 2-methylpropanoate | 3462 | C10 H12 O4 | Colourless to yellow liquid | Insoluble in water; Soluble in propylene glycol and fixed oils | 100° (0.01 mm Hg) | IR | 10.0 | 1.493-1.501 | | 65th/N,T | SG range |
| 1483 | 2-Methyl-3-(1-oxopropoxy)-4H-pyran-4-one | 3941 | C9 H10 O4 | White crystalline solid | Insoluble in water; Soluble in fats | - | NMR IR | - | - | mp: 42-45° | 65th/N,C | |
| 1484 | 2-Butyl-5- or 6-keto-1,4-dioxane | 2204 | C8 H14 O3 | Colourless liquid | Slightly soluble in water | 98-99° | NMR | - | 1.472-1.478 1.292-1.296 | [Lactone undergoes ringopeningin basic solution] | 65th/N | |
| 1485 | 2-Amyl-5 or 6-keto-1,4-dioxane | 2076 | C9 H16 O3 | Colourless liquid | Slightly soluble in water | 101-103° | NMR | - | 1.480-1.486 1.288-1.294 | [Lactone undergoes ringopeningin basic solution] | 65th/N | |
| 1486 | 2-Hexyl-5 or 6-keto-1,4-dioxane | 2574 | C10 H18 O3 186.25 | Colourless or very pale yellow liquid | Slightly soluble in water; Soluble in oil | 104° | NMR | - | 1.486-1.492 1.280-1.286 | [Lactone undergoes ringopeningin basic solution] | 65th/N | |
| 1487 | 2-Methylfuran | 4179 | C5 H6 O | Colourless liquid | Slightly soluble in water | 64° | NMR IR MS | 1.0 | 1.431-1.437 0.908-0.917 | | 65th/N | |
| 1488 | 2,5-Dimethylfuran | 4106 | C6 H8 O | Colourless liquid | Slightly soluble in water | 93° | NMR IR MS | 1.0 | 1.437-1.443 0.892-0.898 | | 65th/N | |
| 1489 | 2-Ethylfuran | 3673 | C6 H8 O | Colourless liquid | Insoluble in water; Soluble in oils | 92-93° | NMR | 1.0 | 1.444-1.450 0.909-0.915 | | 65th/N | |
| 1490 | 2-Butylfuran | 4081 | C8 H12 O | Colourless liquid | Insoluble in water | 139° | MS | 1.0 | 1.444-1.450 0.884-0.890 | | 65th/N | |
| 1491 | 2-Pentylfuran | 3317 | C9 H14 O | Colourless liquid | Slightly soluble in water | 58-60° | NMR | 1.0 | 1.443-1.449 0.886-0.893 | | 65th/N | |
| 1492 | 2-Heptylfuran | 3401 | C11 H18 O | Colourless to yellowish liquid | Insoluble in water | 209-210° | NMR | 1.0 | 1.446-1.452 0.860-0.866 | | 65th/N | |
| 1493 | 2-Decylfuran | 4090 | C14 H24 O | Colourless solid | Insoluble in water | - | NMR (13C) | - | - | mp: 30° | 65th/N | |
| 1494 | 3-Methyl-2-(3-methylbut-2-enyl)-furan | 4174 | C10 H14 O | Colourless liquid | Slightly soluble in water | 70° (11 mm Hg) | MS | 1.0 | 1.473-1.479 | | 65th/N | |
| 1495 | 2,3-Dimethylbenzofuran | 3535 | C10 H10 O | Clear to yellow liquid | Insoluble in water, | 96-98° (15 mm Hg) | NMR | 1.0 | 1.554-1.563 | | 65th/N | |
| 1496 | 2,4-Difurfurylfuran | 4095 | C14 H14 O3 | Colourless solid | Insoluble in water | - | NMR (13C) | - | - | mp: 153° | 65th/N | |
| 1497 | 3-(2-Furyl)acrolein | 2494 | C7 H6 O2 | White or yellow needles | Insoluble in water | - | NMR | 3.0 | - | mp: 49-52° | 65th/N | |
| 1498 | 2-Methyl-3(2-furyl)acrolein | 2704 | C8 H8 O2 | Pale yellowish liquid | Insoluble in water; Soluble in oils | 225° | NMR | 3.0 | 1.567-1.573 | | 65th/N | |
| 1499 | 3-(5-Methyl-2-furyl)prop-2-enal | 4175 | C8 H8 O2 | Colourless liquid | Slightly soluble in water | 101° (5 mm Hg) | NMR | 3.0 | 1.006-1.012 | | 65th/N | |
| 1500 | 3-(5-Methyl-2-furyl)-butanal | 3307 | C9 H12 O2 | Colourless liquid | Insoluble in water; Soluble in oils | 88-91° (12 mm Hg) | NMR | 3.0 | 1.575-1.581 | | 65th/N | |
| 1501 | 2-Furfurylidenebutyralde-hyde | 2492 | C9 H10 O2 | Pale yellowish liquid | Insoluble in water; Soluble in oils | 240° | NMR | 3.0 | 1.570-1.576 | | 65th/N | |
| 1502 | 2-Phenyl-3-(2-furyl)prop-2-enal | 3586 | C13 H10 O2 | White solid | Insoluble in water | - | NMR | - | - | mp: 56-57° | 65th/N | |
| 1503 | 2-Furyl methyl ketone | 3163 | C6 H6 O2 | Yellow to brown liquid | Very slightly soluble in water; | 67° (10 mm Hg) | IR | 1.0 | 1.505-1.510 | | 65th/N | |
| 1504 | 2-Acetyl-5-methylfuran | 3609 | C7 H8 O2 | Colourless liquid | Slightly soluble in water; | 71-72° (8 mm Hg) | NMR IR | 2.0 | 1.511-1.517 | | 65th/N | |
| 1505 | 2-Acetyl-3,5-dimethylfuran | 4071 | C8 H10 O2 | Colourless liquid to solid | Insoluble in water | 195° | MS | 1.0 | 1.494-1.500 | mp: 18° | 65th/N | |
| 1506 | 3-Acetyl-2,5-dimethylfuran | 3391 | C8 H10 O2 | Clear to yellow liquid | Slightly soluble in water; | 83° (11 mm Hg) | NMR | 1.0 | 1.484-1.492 | | 65th/N,T | SG range |
| 1507 | 2-Butyrylfuran | 4083 | C8 H10 O2 | Colourless liquid | Insoluble in water | 195° | MS | 1.0 | 1.489-1.495 | | 65th/N | |
| 1508 | (2-Furyl)-2-propanone | 2496 | C7 H8 O2 | Liquid | Soluble in ether, triacetin | 179-180° | NMR | 1.0 | 1.499-1.505 | | 65th/N | |
| 1509 | 2-Pentanoylfuran | 4192 | C9 H12 O2 | Colourless liquid | Slightly soluble in water | 101° (10 mm Hg) | MS | 1.0 | 1.486-1.492 | | 65th/N | |
| 1510 | 1-(2-Furyl)butan-3-one | 4120 | C8 H10 O2 | Colourless solid | Slightly soluble in water | - | MS | - | - | mp: 37° | 65th/N | |
| 1511 | 4-(2-Furyl)-3-buten-2-one | 2495 | C8 H8 O2 | Colourless needle crystals | Insoluble in water | - | NMR | 1.0 | - | mp: 37-40° | 65th/N | |
| 1512 | Pentyl 2-furyl ketone | 3418 | C10 H14 O2 | Colourless to yellow liquid | Slightly soluble in water | 65-67° (0.5 mm Hg) | NMR | 1.0 | 1.490-1.496 | | 65th/N | |
| 1513 | Ethyl 3-(2-furyl)propanoate | 2435 | C9 H12 O3 | Low melting solid, turning yellow on exposure to air | Very slightly soluble in water | - | NMR | 5.0 | - | mp: 24-25° | 65th/N | |
| 1514 | Isobutyl 3-(2-furan)pro-pionate | 2198 | C11 H16 O3 | Colourless to pale, straw-yellow liquid | Very slightly soluble in water | 105 (3 mm Hg) | NMR | 5.0 | 1.531-1.537 | | 65th/N | |
| 1515 | Isoamyl 3-(2-furan)pro-pionate | 2071 | C12 H18 O3 | Colourless to pale yellow liquid | Insoluble in water | 258° | NMR | 5.0 | 1.549-1.557 | | 65th/N | |
| 1516 | Isoamyl 4-(2-furan)butyrate | 2070 | C13 H20 O3 | Pale yellowish liquid | Insoluble in water | 263-265° | NMR | 5.0 | 1.551-1.555 | | 65th/N | |
| 1517 | Phenethyl 2-furoate | 2865 | C13 H12 O3 | Colourless liquid | Insoluble in water; Soluble in oils | 275° | NMR | 5.0 | 1.585-1.593 | | 65th/N | |
| 1518 | Propyl 2-furanacrylate | 2945 | C10 H12 O3 | Colourless to pale yellow liquid | Insoluble in water | 119° (7 mm Hg) | NMR | 5.0 | 1.520-1.526 | | 65th/N | |
| 1519 | 2,5-Dimethyl-3-oxo-(2H)-fur-4-yl butyrate | 3970 | C10 H14 O4 | Colourless to pale yellow liquid | Insoluble in water | 287° | NMR | 5.0 | 1.467-1.473 | SC: 4-Hydroxy-2,5-dimethylfuran-3-one; Butyric acid | 65th/N | |
| 1520 | Furfuryl methyl ether | 3159 | C6 H8 O2 | Clear to yellow liquid | Insoluble in water; Soluble in ether | 134-135° | NMR | 1.0 | 1.454-1.460 | | 65th/N | |
| 1521 | Ethyl furfuryl ether | 4114 | C7 H10 O2 | Colourless liquid | Slightly soluble in water | 150° | MS | 1.0 | 1.449-1.455 | | 65th/N | |
| 1522 | Difurfuryl ether | 3337 | C10 H10 O3 | Colourless to yellow liquid | Insoluble in water | 88-89° (1 mm Hg) | NMR | 1.0 | 1.138-1.144 | | 65th/N | |
| 1523 | 2,5-Dimethyl-3-furanthiol acetate | 4034 | C8 H10 O2 S | Colourless liquid | Practically insoluble in water and hexane; Soluble in ether | 230° | IR MS NMR | 5.0 | 1.527-1.533 | | 65th/N | |
| 1524 | Furfuryl 2-methyl-3-furyl disulfide | 4119 | C10 H10 O2 | Colourless liquid | Slightly soluble in water; Soluble in pentane, diethyl ether | 294° | IR NMR | 3.0 | 1.581-1.587 | SC: Di-(2-methyl-3-furyl) disulfide | 65th/N | |
| 1525 | 3-[(2-Methyl-3-furyl)thio]-2-butanone | 4056 | C9 H12 O2 S 184.25 | Colourless liquid | Soluble in ethyl acetate, triacetin, Practically insoluble in water | 70° (0.75 mm Hg) | NMR MS | 1.0 | 1.510-1.516 | | 65th/N | |
| 1526 | O-Ethyl S-(2-furylmethyl)thiocarbonate | 4043 | C8 H10 O3 S | Colourless liquid | Practically insoluble in water; Soluble in diether ether, ethyl acetate | 130-135° | NMR IR MS | 5.0 | 1.504-1.510 | | 65th/N | |
| 1527 | 4-Allylphenol | 4075 | C9 H10 O | Colourless liquid | Insoluble in water | 235° | NMR | 1.0 | 1.542-1.548 | | 65th/N,C | |
| 1528 | 2-Methoxy-6-(2-propenyl)phenol | 579-60-2 | C10 H12 O2 | Colourless to pale yellow liquid | Slightly soluble in water; Soluble in ether, most fixed oils | 119-121° (12 mm Hg) | NMR | 1.0 | 1.535-1.541 | | 65th/N,C | |
| 1529 | Eugenol | 2467 | C10 H12 O2 | Colourless to pale yellow liquid | Slightly soluble in water; Soluble in ether, most fixed oils | 256° | IR | 1.0 | 1.540-1.542 | | 65th/R | |
| 1530 | Eugenyl formate | 2473 | C11 H12 O3 | Colourless to pale-yellowish oily liquid | Insoluble in water; Soluble in oils | 270° | NMR | 1.0 | 1.524-1.526 | SC: Eugenol | 65th/N | |
| 1531 | Eugenyl acetate | 2469 | C12 H14 O3 | Fused solid, melts at warm room temperature to a pale yellow liquid | Insoluble in water; Soluble in ether, fixed oils | 282° | IR | 1.0 | 1.514-1.522 | mp: 25° | 65th/N | |
| 1532 | Eugenyl isovalerate | 4118 | C15 H20 O3 | White solid | Insoluble in water | - | NMR | - | - | mp: 85° | 65th/N,C | |
| 1533 | Eugenyl benzoate | 2471 | C17 H16 O3 | Colourless crystalline solid | Insoluble in water; Soluble in oils | - | NMR | - | - | mp: 69-70° | 65th/N | |
| 1534 | Methyl anthranilate | 2682 | C8 H9 N O2 | Colourless to pale yellow liquid or crystals with bluish fluorescence | Soluble in oils and propylene glycol; Insoluble in glycerol; Slightly soluble in water Soluble | 256° | IR | 1.0 | 1.581-1.585 | | 65th/R | |
| 1535 | Ethyl anthranilate | 2421 | C9 H11 N O2 | Colourless to light yellow liquid | Slightly soluble in water; Soluble in propylene glycol and fixed oils Soluble | 267° | IR | 1.0 | 1.563-1.566 | | 65th/N | |
| 1536 | Butyl anthranilate | 2181 | C11 H15 N O2 | A colourless or very pale straw-Coloured liquid | Insoluble in water; Soluble in oils | 303° | NMR | 1.0 | 1.539-1.545 | | 65th/N | |
| 1537 | Isobutyl anthranilate | 2182 | C11 H15 N O2 | Colourless to pale yellow liquid | Insoluble in water; Soluble in oils | 169-170° (13.5 mm Hg) | NMR | 1.0 | 1.534-1.540 | | 65th/N | |
| 1538 | cis-3-Hexenyl anthranilate | 3925 | C13 H17 N O2 | Colourless liquid | Insoluble in water; Soluble in fats | 160° (5 mm Hg) | NMR IR | 2.0 | 1.545-1.554 | | 65th/N,C | |
| 1539 | Citronellyl anthranilate | 4086 | C17 H25 N O2 | Colourless liquid | Insoluble in water | 160° (0.1 mm Hg) | NMR | 1.0 | 1.531-1.537 | | 65th/N,C | |
| 1540 | Linalyl anthranilate | 2637 | C17 H23 N O2 | Pale straw-coloured oily liquid | Insoluble in water; Soluble in dimethyl sulphoxide | 370-371° | NMR | 2.0 | 1.516-1.522 | | 65th/N | |
| 1541 | Cyclohexyl anthranilate Cyclohexyl 2-aminobenzoate | 2350 | C13 H17 N O2 | Pale yellow liquid | Insoluble in water | 318° | NMR | 1.0 | 1.571-1.577 | | 65th/N | |
| 1542 | beta-Terpinyl anthranilate | 3048 | C17 H23 N O2 | Colourless to yellow liquid | Insoluble in water; Soluble in fats | 365° | NMR | 2.0 | 1.480-1.486 | | 65th/N | |
| 1543 | Phenylethyl anthranilate | 2859 | C15 H15 N O2 | Fused, colourless to pale yellow-amber crystaline mass | Insoluble in water | - | IR | - | - | mp: 40° | 65th/N | |
| 1544 | beta-Naphthyl anthranilate | 2767 | C17 H13 N O2 | Colourless to pale straw | Insoluble in water | 340° | NMR | 2.0 | 1.531-1.539 | | 65th/N | |
| 1545 | Methyl N-methylanthranilate | 2718 | C9 H11 N O2 | Pale yellow liquid with bluish fluorescence | Insoluble in water; Slightly soluble in glycerol; Soluble in oils | 256° | NMR | 1.0 | 1.577-1.583 | | 65th/R | |
| 1546 | Ethyl N-methylanthranilate | 4116 | C10 H13 N O2 | Yellowish solid | Very slightly soluble in water | - | NMR | 1.0 | - | | mp: 36° | 65th/N,C |
| 1547 | Ethyl N-ethylanthranilate | 4115 | C11 H15 N O2 | Yellowish solid | Very Slightly soluble in water | - | NMR | 1.0 | - | | mp: 74° | 65th/N,C |
| 1548 | Isobutyl N-methylanthrani-late | 4149 | C12 H17 N O2 | Yellowish solid | Very slightly soluble in water | - | NMR | 1.0 | - | | mp: 70° | 65th/N,C |
| 1549 | Methyl N-formylanthranilate | 4171 | C9 H9 N O3 | Yellowish solid | Slightly soluble in water | - | NMR | 2.0 | - | | mp: 53° | 65th/N,C |
| 1550 | Methyl N-acetylanthranilate | 4170 | C10 H11 N O3 | White to light yellow crystals | Slightly soluble in water | - | NMR | - | - | mp: 98-101° | 65th/N,C | |
| 1551 | Methyl N,N-dimethylanthranilate | 4169 | C10 H13 N O2 | Yellowish liquid to solid | Very slightly soluble in water | 141° (15 mm Hg) | NMR | 1.0 | 1.551-1.557 | mp: 18° | 65th/N,C | |
| 1552 | N-Benzoylanthranilic acid | 4078 | C14 H11 N O3 | White solid fruity aroma | Slightly soluble in water | - | NMR IR MS | 3.0 | - | mp: 183° | 65th/N,C | |
| 1553 | Trimethyloxazole Trimethyloxazole | 13.169 | C6 H9 N O | Yellowish liquid | Insoluble in water | 134° | NMR | - | 1.438-1.446 | | 65th/N,C | |
| 1554 | 2,5-Dimethyl-4-ethyloxazole | 13.118 | C7 H11 N O | Yellowish liquid | Insoluble in water | 150° | NMR | - | 1.441-1.447 | | 65th/N,C | |
| 1555 | 2-Ethyl-4,5-dimethyloxazole | 3672 | C7 H11 N O | Colourless liquid | Insoluble in water; Slightly soluble in oils | 137° (732 mm Hg) | NMR | - | 1.454-1.460 | | 65th/N,C | |
| 1556 | 2-Isobutyl-4,5-dimethyl-oxazole | 26131-91-9 | C9 H15 N O | Yellowish liquid | Insoluble in water | 227° | NMR | - | 1.439-1.447 | | 65th/N,C | |
| 1557 | 2-Methyl-4,5-benzo-oxazole | 13.154 | C8 H7 N O | Yellowish liquid | Insoluble in water | 199° | NMR | - | 1.544-1.550 | | 65th/N,C | |
| 1558 | 2,4-Dimethyl-3-oxazoline | 13.115 | C5 H9 N O | Yellowish liquid | Insoluble in water | 141° | NMR | - | 1.431-1.437 | | 65th/N,C | |
| 1559 | 2,4,5-Trimethyl-delta-3-oxazoline | 3525 | C6 H11 N O | Yellow orange liquid | Soluble in water, propylene glycol; Insoluble in most fixed oils | 96-97° | NMR | - | 1.414-1.435 | SC: Trimethyloxazole | 65th/N,T | RI range; SG range |
| 1560 | Allyl isothiocyanate | 2034 | C4 H5 N S | Colourless or pale yellow liquid | Slightly soluble in water; Soluble in ether | 150-151° | IR | 1.0 | 1.524-1.531 | | 65th/N | |
| 1561 | Butyl isothiocyanate | 4082 | C5 H9 N S | Yellowish liquid | Insoluble in water | 167° | NMR | 1.0 | 1.492-1.498 | | 65th/N,C | |
| 1562 | Benzyl isothiocyanate | 12.102 | C8 H7 N S | Pale yellowish liquid | Insoluble in water | 243° | NMR | 1.0 | 1.600-1.606 | | 65th/N,C | |
| 1563 | Phenethyl isothiocyanate | 4014 | C9 H9 N S | Nearly Colourless liquid | Insoluble in water; Soluble in triacetin and heptane | 139-140° | NMR IR MS | 1.0 | 1.586-1.590 | | 65th/N,C | |
| 1564 | 3-Methylthiopropyl isothiocyanate | 3312 | C5 H9 N S2 | Colourless to yellow liquid | Insoluble in water | 254° | NMR | 1.0 | 1.560-1.566 | | 65th/N | |
| 1565 | 4-Acetyl-2-methylpyrimidine | 3654 | C7 H8 N2 O | Colourless liquid | Slightly soluble in water; Soluble in fats | 87-89° (10 mm Hg) | NMR | 1.0 | 1.501-1.507 | | 65th/N | |
| 1566 | 5,7-Dihydro-2-methyl-thieno(3,4-d)pyrimidine | 3338 | C7 H8 N2 S | Solid | Very slighlty soluble in water | | NMR | - | - | mp: 64° | 65th/N | |
| 1568 | 1-Phenyl-3 or 5-propyl-pyrazole | 3727 | C12 H14 N2 | Colourless to yellow liquid | Insoluble in water | 182-193° | NMR | - | 1.428-1.436 | | 65th/N | |
| 1569 | 4,5-Dimethyl-2-propyloxazole | 13.112 | C8 H13 N O | Yellowish solid | Slightly soluble in water | - | NMR | - | - | mp: 59° | 65th/N,C | |
| 1570 | 4,5-Epoxy-(E)-2-decenal | 4037 | C10 H16 O2 | Clear liquid | Soluble in water | 80-83° (0.65 mm Hg) | NMR IR | 3.0 | 1.472-1.478 | SC: cis isomer | 65th/N,C | |
| 1571 | beta-Ionone epoxide | 4144 | C13 H20 O2 | Colourless solid | Insoluble in water | - | NMR MS | - | - | mp: 48° | 65th/N,C | |
| 1572 | cis-Carvone-5,6-oxide | 4084 | C10 H14 O2 | Colourless liquid | Insoluble in water | 105° (5 mm Hg) | NMR MS | 1.0 | 1.481-1.487 | | 65th/N | |
| 1573 | Epoxyoxophorone | 4109 | C9 H12 O3 | Colourless solid | Insoluble in water | - | NMR | - | - | mp: 157° | 65th/N,C | |
| 1574 | Piperitenone oxide | 4199 | C9 H14 O2 | Colourless solid | Soluble in water | - | NMR MS | 1.0 | - | mp: 25° | 65th/N | |
| 1575 | beta-Caryophyllene oxide | 4085 | C15 H24 O | Colourless solid | Insoluble in water | - | NMR MS | - | - | mp: 61° | 65th/N | |
| 1576 | Ethyl 3-phenylglycidate | 2454 | C11 H12 O3 | Clear, Colourless to pale yellow liquid | Insoluble in water; Soluble in ether, oils | 96° (0.5 mm Hg) | IR | 2.0 | 1.516-1.521 | | 65th/R | |
| 1577 | Ethyl methylphenylglycidate | 2444 | C12 H14 O3 | Colourless to pale yellow liquid | Insoluble in water, glycerol; Soluble in propylene glycol, fixed oils | 272-275° | IR | 2.0 | 1.504-1.513 | | 65th/R | |
| 1578 | Ethyl methyl-p-tolylglycidate | 3757 | C13 H16 O3 | Colourless or pale straw | Insoluble in water; Soluble in ether, oils | 123-125° | NMR | 2.0 | 1.523-1.529 | | 65th/N | |
| 1579 | Ethylamine | 4236 | C2 H7 N | Colourless to yellow gas | Soluble in water | 17° | MS | - | - | mp: -81° | 65th/N,C | |
| 1580 | Propylamine | 4237 | C3 H9 N | Colourless to yellow liquid | Soluble in water | 48° | MS | - | 1.384-1.390 | | 65th/N,C | |
| 1581 | Isopropylamine | 4238 | C3 H9 N | Colourless to yellow liquid | Soluble in water | 34° | MS | - | 1.367-1.373 | | 65th/N,C | |
| 1582 | Butylamine | 3130 | C4 H11 N | Colourless liquid, tends to yellow on | Soluble in water | 78° | NMR | - | 1.398-1.404 | | 65th/N | |
| 1583 | Isobutylamine | 4239 | C4 H11 N | Colourless to yellow liquid | Soluble in water | 68° | MS | - | 1.391-1.397 | | 65th/N,C | |
| 1584 | sec-Butylamine | 4240 | C4 H11 N | Colourless to yellow liquid | Soluble in water | 63° | MS | - | 1.387-1.393 | | 65th/N,C | |
| 1585 | Pentylamine | 4242 | C5 H13 N | Colourless to yellow liquid | Soluble in water | 103° | MS | - | 1.418-1.424 | | 65th/N,C | |
| 1586 | 2-Methylbutylamine | 4241 | C5 H13 N | Colourless to yellowish liquid | Soluble in water | 96° | MS | - | 1.417-1.423 | | 65th/N,C | |
| 1587 | Isopentylamine | 3219 | C5 H13 N | Colourless or very pale straw-Coloured mobile liquid | Soluble in water, propylene glycol, glycerin, oils | 95-97° | NMR | - | 1.405-1.411 | | 65th/N | |
| 1588 | Hexylamine | 4243 | C6 H15 N | Colourless to yellow liquid | Soluble in water | 130° | MS | - | 1.415-1.421 | | 65th/N,C | |
| 1589 | Phenethylamine | 3220 | C8 H11 N | Colourless to pale, slightly yellow liquid | Soluble in water, ether | 194-195° | NMR | - | 1.526-1.532 (25°) | | 65th/N | |
| 1590 | 2-(4-Hydroxyphenyl)ethyl-amine | 4215 | C8 H11 N O | Colourless to yellow solid | Soluble in water | - | MS | - | | - mp: 165° | 65th/N,C | |
| 1591 | 1-Amino-2-propanol | 3965 | C3 H9 N O | Colourless to faint yellow liquid | Soluble in water | 160° | NMR | 1.0 | 1.445-1.451 | | 65th/N,C | |
| 1593 | Butyramide | 4252 | C4 H9 N O | Yellowish solid | Soluble in water | - | NMR | - | - | mp: 115° | 65th/N,C | |
| 1594 | 1,6-Hexalactam | 4235 | C6 H11 N O | Yellowish solid | Soluble in water | - | NMR | - | - | mp: 70° | 65th/N,C | |
| 1595 | 2-Isopropyl-N,2,3-trimethylbutyramide | 3804 | C10 H21 N O | White crystalline solid | Insoluble in water and fats; Soluble in diethyl ether, and hydrocarbons | - | NMR | 1.0 | - | mp: 56-64° | 65th/N,C | |
| 1596 | N-Ethyl (E)-2,(Z)-6-nonadienamide | 4113 | C11 H19 N O | Pale yellow to yellow viscous liquid | Sparingly soluble in water | 120° (0.6 mm Hg) | NMR IR MS | 3.0 | 1.484-1.493 | | 65th/N,C | |
| 1597 | N-Cyclopropyl (E)-2,(Z)-6-nonadienamide | 4087 | C12 H19 N O | Pale yellow low melting solid | Sparingly soluble in water | - | NMR IR | - | - | mp: 33-37° | 65th/N,C | |
| 1598 | N-Isobutyl (E,E)-2,4-decadienamide | 4148 | C14 H25 N O | Colourless off-white to yellow solid | Insoluble in water Soluble | - | NMR IR MS | 5.0 | - | mp: 82-90° | 65th/N,C | |
| 1599 | Nonanoyl 4-hydroxy-3-methoxybenzylamide | 2787 | C17 H27 N O3 | White powder or crystals odourless | Slightly soluble in water Soluble | - | NMR | 1.0 | - | mp 124-128° | 65th/N | |
| 1600 | Piperine | 2909 | C17 H19 N O3 | Virtually colourless white crystals | Very slightly soluble in water; Soluble in ether, oils Soluble | - | NMR | - | - | mp: 128-130° | 65th/N | |
| 1601 | N-Ethyl 2-isopropyl-5-methyl-cyclohexanecarboxamide | 16.013 | C13 H25 N O | White solid | Insoluble in water Soluble | - | NMR | - | - | mp: 91-93° | 65th/N | |
| 1602 | (+/-)-N,N-Dimethyl menthyl succinamide | 4231 | C16 H30 N2 O2 | Clear yellow to orange liquid | Slightly soluble in water Soluble | 380° | IR NMR | 3.0 | 1.522-1.530 | | 65th/N,C | |
| 1603 | 1-Pyrroline | 3898 | C4 H7 N | Colourless liquid | Soluble in water Soluble | 87-89° | NMR | 1.0 | 1.440-1.446 | | 65th/N,C | |
| 1604 | 2-Acetyl-1-pyrroline | 4249 | C6 H9 N O | Colourless to yellow solid | Soluble in water Soluble | - | MS | - | - | mp: 19° | 65th/N,C | |
| 1605 | 2-Propionylpyrroline | 4063 | C7 H11 N O | Yellowish liquid | Soluble in heptane, triacetin Soluble | 89-90° (1 mm Hg) | NMR IR MS | - | 1.446-1.452 | [Material is provided as a 1% solution in vegatable oil triglyceride] | 65th/N,C | |
| | | | | | | | | | | | | |
| 1606 | Isopentylidene isopentylamine | 3990 | C10 H21 N | Clear, Colourless liquid | Insoluble in water; Soluble in heptane, triacetin | 145-148° | NMR IR MS | - | -1.422-1.428 0.768-0.774 | SC: Diisopentylamine; 3-Methylbutyralde-hyde | 65th/N,C | |
| 1607 | Piperidine | 2908 | C5 H11 N | Colourless to pale yellow liquid | Soluble in water, ether | 106° | IR | - | -1.450-1.454 0.858-0.862 | | 65th/N | |
| 1608 | 2-Methylpiperidine | 4244 | C6 H13 N | Colourless to yellow liquid | Soluble in water | 118° | MS | - | -1.442-1.448 0.838-0.844 | | 65th/N,C | |
| 1609 | Pyrrolidine | 3523 | C4 H9 N | Colourless liquid | Soluble in water, fats | 87-89° | NMR IR | - | -1.440-1.446 0.847-0.853 | | 65th/N | |
| 1610 | Trimethylamine | 3241 | C3 H9 N | Colourless gas | Soluble in water, ether | 3-4° | NMR | - | - 0.667-0.675 (4°) | | 65th/N | |
| 1611 | Triethylamine | 4246 | C6 H15 N | Colourless to yellowish liquid | Soluble in water | 88° | MS | - | -1.395-1.401 0.724-0.730 | | 65th/N,C | |
| 1612 | Tripropylamine | 4247 | C9 H21 N | Colourless to fishy liquid | Soluble in water | 156° | MS | - | -1.411-1.417 0.754-0.760 | | 65th/N,C | |
| 1613 | N,N-Dimethylphenethylamine N,N-Dimethylphenethylamine | 4248 | C10 H15 N | Colourless to yellow liquid | Soluble in water | 183° | MS | - | -1.500-1.506 0.898-0.904 | | 65th/N,C | |
| 1614 | Trimethylamine oxide | 4245 | C3 H9 N O | Colourless to yellow solid | Soluble in water | - | MS | - | - | mp: 213° | 65th/N,C | |
| 1615 | Piperazine | 4250 | C4 H10 N2 | Colourless to yellow solid | Soluble in water | - | MS | - | - | mp: 109° | 65th/N,C | |
