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APHCA special session on avian influenza
(APHCA 2005/07)

Global strategy for the control of avian influenza in Asia
... tackling the disease at source...
Presented by Juan Lubroth (AGAH Senior Officer, FAO/ROME)

Slide 1

APHCA 29th Session

Global Strategy for the Control of Avian Influenza in Asia

... Tackling the Disease at Source...

Bali, Indonesia - September 2005

Slide 2


  • Emergency Expert Consultation on the Control of Avian Influenza
  • Rome, 3-4 February 2004

  • Regional Meetings on Avian Influenza in Animals in Asia
  • Bangkok, Thailand, 26-28 February 2004
  • Ho Chi Minh City, 23-25 February 2005

  • Coordination Meeting between WHO, OIE and FAO
  • Venice, September 2004

  • OIE/FAO, WHO International Scientific Conference on AI
  • Paris, 7-8 April 2005

Slide 3


  • Establishment of the OIE/FAO Avian Influenza Network ("OFFLU")
  • Secretariat at IZS, Padua, ITALY

  • Consultative Workshop:
  • Review on Draft Global Strategy for the Control of HPAI
  • Bangkok on 17-18 May 2005

  • FAO/WHO/OIE Regional Meeting on Human/Veterinary Inferface
  • Kuala Lumpur, 4-6 July 2005

Slide 4

Emerging pattern

Slide 5

Imminent Pandemic?

  • Wall Street Journal - 2 August 2005
  • "Experts Say World Isn't Ready To Defend itself Against Flu" by David Brown

  • The FAO and OIE focus is on diminishing the risk of a pandemic by tackling the disease at source
  • Poultry; Asia

  • GF-TADs - The Global Framework for the Progressive Control of Transboundary Animal Diseases

Slide 6

Type of Farming system

Slide 7

Conclusions of 2004/2005 Activities

  • Asia versus Europe/N America

  • Country and Regional specific epidemiological analysis

  • HPAI Country situation assessments

  • Definition of country specific strategies for HPAI control

    - Concept Notes

Slide 8

Results of 2004/2005 Activities

  • Socio Economic impact assessments

  • Compensation studies

  • Market chain studies

  • Policies/Poultry Sector Restructuring

  • Wildlife field studies

  • Vaccine pilot studies

  • With OIE and WHO... human/animal interface

Slide 9

A Global Strategy for the
Progressive Control of Highly
Pathogenic Avian Influenza

Slide 10

Why a global strategy?

  • HPAI is highly infectious and labile disease

    - The emergence of the current H5N1 Z genotype can be attributed to this phenomenon

  • HPAI results from low pathogenic avian influenza (LPAI), which is present in wild birds in many parts of the world. All countries in the world are at risk of being infected unexpectedly

Slide 11

Why a global strategy?

  • HPAI has emerged and spread rapidly as consequence of globalized markets

  • HPAI is zoonotic and transboundary in nature

    - Protecting human health is an international responsibility
    - WHO: " 7 million people could die of the pandemic"

Slide 12

Avian Influenza: A human disease


Total cases

















WHO - 22 September 2005

Slide 13

Why a global strategy?

  • HPAI threatens regional and international trade

    - $1.2 billion in Thailand (4th largest poultry exporting country in the world)
    - $200 million in Vietnam
    - $170 million in Indonesia
    - Total estimated to be $10-15 billion in Asia

  • HPAI control beyond the scope and resources of a single country or region

Slide 14

  • Endemicity

  • H5N1 avian influenza viruses are now established in several countries of Asia, persisting in farmed and wild waterfowl, particularly ducks, and in the multiple avian species found in live bird markets

  • The role of ducks as a reservoir of infection, causing persistence and spread of avian influenza is well recognised.

... Total eradication will be very difficult

Slide 15

A Global Strategy for the Progressive Control of Highly Pathogenic Avian Influenza

  • Asia as a priority

  • National

  • Regional

  • International Levels

  • Networking

  • Information exchange and concerted action

Slide 16

The global strategy in perspective

  • All countries in the world are at risk of being infected

  • HPAI has emerged and spreads rapidly as consequence of globalised markets

  • HPAI is zoonotic and transboundary in nature

    - Protecting human health is an international responsibility
    - WHO: " 7 million people could die of the pandemic"

Slide 17

The global strategy in perspective

  • Livelihoods of poor farmers threatened

    - 80% population live in rural areas
    - Large numbers depend on poultry (136-210 million)
    - At risk countries have dense populations.
    - Rapid spread in India or Bangladesh of HPAI could devastating and present an even increased risk to the rest of the world

Slide 18

What are the major constraints?

  • Inexperience

    - Magnitude and logistics

  • Inadequate depth in veterinary services

    - Insufficient expertise in epidemiology, diagnosis, emergency response
    - Inadequate disease information systems

  • Endemic nature of the disease

    • Poor understanding of the source
    • Lack of information on infection and transmission dynamics
    • Difficult to detect sub-clinical infection (farmed ducks, waterfowl)

  • Poor production biosecurity
  • Lack of data on disease impacts
  • Need for long term regional coordination

Slide 19


Slide 20


Country level

  • Develop strategies for each affected country

    - Stakeholders
    - Vaccination and Logistics
    - Surveillance Techniques

  • Prevent introduction of HPAI in non-infected at risk countries

    - Awareness and reporting
    - Early Detection

  • Improve epidemiological information

    - Source
    - Disease infection and transmission dynamics

    • On the farming systems
    • At the Market place

  • Prepare contingency and emergency preparedness plans
  • Develop economic and policy frameworks for reform

Slide 21


Country level

  • Improve long-term capacity

    - Diagnosis
    - Epidemiology
    - Disease surveillance
    - Disease reporting
    - Disease information systems
    - Emergency preparedness plans
    - Economic and policy analysis

Slide 22

Regional Level

  • Institutionalized and inter-sectoral coordination

  • Programme management

  • Regional capacity building in diagnosis, surveillance and epidemiology, policy and socio-economic impact assessment

  • Public awareness

  • Research and development

Slide 23

Regional Level

  • Standardization

    - diagnosis
    - surveillance and monitoring protocols
    - disease reporting
    - emergency preparedness planning

  • Disease information sharing

  • Regulatory frameworks for the management of animal movement

  • Adherence to OIE guidelines to facilitate regional trade

Slide 24

International Level

  • Strengthen partnership among international organizations (FAO, OIE and WHO)

  • Analytical support and coordination of the subregional networks

  • Develop the Global Early Warning System (GLEWS) that incorporates other factors than disease presence

  • Provision of backstopping to support subregional networks - FAO HQ, OIE/FAO epidemiology collaborating centres, Reference Laboratories and OFFLU

Slide 25

International Level

  • Coordinating research needs and evaluation in improved tools for HPAI control

  • Provide a global vision for HPAI control (e.g. EMPRES’ GREP, EU FMD, CSF Americas)

  • Mobilize and allocate resources for HPAI control and prevention through active donor liaison and advocacy

Slide 26

Policy & Regulatory issues

  • Implementation of biosecurity measures

  • Animal movement (national, transboundary)

  • Reporting the disease

  • Sharing information

  • Slaughtering and safe disposal of carcasses

  • Compensation issues

  • Restructuring and readjustment of the poultry industry

  • Compartmentalization and zoning

  • Control of certain risky traditional practices

Slide 27

Capacity building

  • Development of a strong, sustainable human resource base

  • Veterinary Services (and Public Health Services)

  • Skills in disease management

  • Diagnosis and active surveillance

  • Vaccine delivery

  • Epidemiology and disease monitoring

  • Village-based animal health worker training

  • Socio Economic analysis

  • Policy development and risk analysis

Slide 28


  • HPAI spread in humans and poultry will be contained

  • HPAI incidence in poultry will be progressively reduced

  • Progressive HPAI eradication in compartments and zones

  • Prevention of establishment of HPAI in non-infected countries (improved capacity for TADs and emerging diseases)

  • Emergency preparedness plans for all countries in Asia

Slide 29


  • Global pandemic of HPAI averted

  • Livelihoods of over 500 million poor smallholder farmers in Asia safeguarded

  • Improved market opportunities for poultry producers at all economic levels

Slide 30


  • Participating countries

    - Infected and non-infected countries in Asia

  • Regional Organizations (ASEAN, ASEAN+3, and SAARC)

  • International Organizations (FAO, OIE and WHO)

  • Private Sector

  • Donors

  • National Agriculture Research and Extension Systems

  • NGOs

Slide 31

Global Framework for the Progressive
Control of Transboundary Animal


Slide 32

Slide 33

GOAL of GF-TADs = Vision Development Objective

  • To improve the protein food security, alleviate poverty, and improve the incomes of developing countries

  • Safeguard the world livestock industry (of developed as well as developing countries) from repeated shocks of infectious disease epidemics

  • Promoting safe and globalised trade in livestock and animal products

Slide 34

Regional Support Units

Slide 35

Concepts and key epidemiological aspects of GF-TADs

  • Disease and Infection at the SOURCE

  • Upstream investigation

  • Epidemiology ~ Laboratory Networks

  • Knowledge on animal production, land usage, marketing schemes, movement patterns... an integrated approach.

  • GLobal Early Warning System FAO-OIE-WHO

Slide 36

Slide 37

Indicator diseases

  • NENA - FMD, rinderpest, HPAI, PPR, sheeppox

  • Tropical Africa FMD, rinderpest, CBPP, PPR, ASF, RVF, Newcastle disease

  • SADC FMD, CBPP, ASF, and Newcastle disease

  • Eastern Asia - FMD, HPAI and CSF

  • South Asia FMD, HP Avian Influenza, rinderpest, PPR, and Newcastle disease

  • Central Asia - HPAI, FMD, rinderpest, and PPR

  • South America - FMD, HPAI, BSE, NWSW, and CSF

  • Central America & Caribbean - FMD-free region; CSF

  • South-Eastern Europe - FMD and CSF

  • Others of concern - brucellosis, rabies...

Slide 38

Inform and Communicate

Update on HPAI situation in Asia
Presented by Carolyn Benigno (Animal Health Officer, FAO/RAP)

Slide 1

Update on HPAI situation in Asia

FAO Regional Office for Asia and the Pacific

Slide 2

Country Situation

Outbreaks reported in Vietnam, Thailand and Indonesia. Vietnam

  • First wave: December 2003 to March 30, 2004

    • 43.9 M chickens, water fowls destroyed, died, 14.76 M quails destroyed in 57 provinces

  • Second outbreak from April to November 2004

    • 84000 birds destroyed in 17 provinces

  • The third wave from December 2004 to date

    • 470,000 chicken, more than 825,000 ducks, and 551,000 quails were destroyed in 36 provinces
    • Vaccination commenced September 2005, expected cost USD 35M

Slide 3

Country Situation


  • Second Nationwide Active surveillance Campaign conducted in July 2005

  • Supanburi, Kamphang Pet, Saraburi


  • Reported in 21 out of 30 Indonesian provinces

  • New cases in four provinces (Jambi, South Sulawesi, East Kalimantan, North Sumatra)

  • Reported human deaths in July, September

Slide 4

Country Situation


  • No reports of HPAI outbreaks

  • Three main markets in Phnom Penh still under surveillance (Chbar Ampeov, O’Russey, Central Market)

  • Human cases reported in April 2005


  • No reports of HPAI outbreaks

Slide 5

Country Situation


  • July 2005 - H5 virus infection was suspected in ducks in a province north of Manila. No mortalities, ducks were apparently healthy.

  • Chickens were negative to HI test.

  • Poultry and ducks were culled.

  • Tissue samples were sent to AAHL and found negative for virus isolation.

Slide 6

Country Situation

Outbreaks reported in DPRK, Russia, China, Mongolia, Japan (low path. strain) and Kazakhstan.

Slide 7

Human Cases
(as of 22 Sept 2005)

  • Vietnam - 90 (63 fatality Dec 04 - Jun 05)

  • Thailand - 17

  • Cambodia - 4

  • Indonesia - 4

Slide 8

Slide 9

Slide 10

Up close and official for an update

Update: sub-regional networks on disease surveillance and diagnosis in Asia
Presented by Wantanee Kalpravidh
(Regional Coordinator TCP/RAS/3006, FAO/RAP)

Slide 1

Update: sub-regional networks on
disease surveillance and diagnosis
in Asia

Wantanee Kalpravidh
Mohinder Oberoi
Fusheng Guo
Regional Coordinators
AI Surveillance and Diagnostic Laboratory Networks in Asia

Slide 2

Areas for Regional Collaboration

  • Laboratory diagnosis

  • Surveillance and Epidemiology analysis

  • Control of AI

  • Preparedness for non-affected countries

  • Establishment of linkage with public health: preparedness for pandemic human influenza

  • Socio-economic assessment

  • Rehabilitation and Restructuring of poultry production system

  • Research

Slide 3

FAO Regional TCPs


Diagnostic laboratory and surveillance network coordination for control and prevention of AI in SE Asia


Diagnostic laboratory and surveillance network coordination for control and prevention of AI in East Asia


Diagnostic laboratory and surveillance network coordination for control and prevention of AI in South Asia


Emergency regional coordination assistance for control of AI in SE Asia


Emergency regional support for post-avian influenza rehabilitation


Strengthening AI control through improved transboundary animal disease information management system in Asia

Slide 4

Sub-regional TCPs for Networking

· TCP/RAS/3006 (10)

· July 2004 - Thailand

· TCP/RAS/3007 (4)

· October 2004 - China

· TCP/RAS/3008 (8)

· August 2005 -India

@ "Guiding Principles on Surveillance and Laboratory Diagnosis"

- developed by during expert consultation meeting in July 2004
- adopted as the minimal requirements - by all sub-regions

@ Identifying gaps for surveillance and laboratory capacities
@ Building capacities based on the gaps

Slide 5

Additional Recommendations from the East and South Asia Launching Meetings

· East Asia:

  • Ideal Capability for a national Laboratory

    - Maintenance of a virus bank (stock of virus antigen)

    - Genetic sequence database for virus isolates

    - Sharing virus with leading laboratory (Harbin Veterinary Research Institute) and Reference Laboratory

· South Asia:

  • Additional focus on:

    - H5 and H7

    - Preparedness for emergency response

    - Awareness to public/stakeholders to achieve surveillance

    - Migratory birds

Slide 6

Scheme of collaboration for Sub-regional Networking in Asia

  • Experts:

  • Training and Workshop

  • Facilitate regional networking

  • Facilitate regional collaboration

Slide 7


  • Experts:

- Epidemiology Consortium:

  • CIRAD, RVC, Massey University
  • Free University, Belgium, etc.

- Laboratory Consultancy:

  • Australian Animal Health Laboratory

- To provide following services:

  • Organize training/workshop to improve the knowledge
  • Harmonize the methodology

  • Publications and Reports:

- Studies: Epidemiology of AI: Country and Regional Status

Slide 8

Training and Workshops

  • Epidemiology:

    - FAO training courses on

    • Basic epidemiology and data analysis: June and September 2005
    • Advanced epidemiology and data analysis: June and September 2005

      - for countries in SE Asia, E Asia and S Asia

    • Advanced Epidemiological Techniques for Regional Hubs in Asia: July 2005

  • Laboratory:

  • - 2 JICA/FAO/DVS training courses in Malaysia: December 2004 and July 2005
    - FAO regional workshop on laboratory networking: to be organized before the end of 2005

  • Preparedness for non-affected countries in Asia: to be organized in October 18-21

  • - Mostly participated by:

    • 8 countries in South Asia and
    • 4 countries in Southeast Asia

Slide 9

Facilitation of Regional and International Networking

  • Information sharing

  • Sharing of regional experts

  • Sharing samples with International Reference Laboratories

  • Collaboration with other TCPs and/or certain Research Agencies:

    - Production, Ecology and Spread of AI
    - Socio-economic Impact Analysis of AI Control Measures

  • Collaboration with OIE and other UN organizations such as WHO, UNDP mainly for the purpose of preparedness for pandemic human influenza

Slide 10

Facilitation of regional collaboration

  • Participation the Meetings of Regional Organizations:

    - ASEAN
    - SAARC
    - ASEAN +3 (to be planned)

  • Sponsoring certain countries to participate in such regional meetings

  • Communication, coordination and collaboration with the Regional Organizations

Slide 11


  • Country: affected and non-affected countries

  • Regional Organization: ASEAN, ASEAN+3, SAARC

  • International Donors and Organizations:

    - Japan, Australia, France, Germany, Canada, USA, Netherlands, etc.
    - FAO, OIE and WHO
    - ADB, World Bank
    - Etc.

Slide 12

  • Countries in the region have made good progress in managing the epidemic. With support of the international community, they have significantly improved their capacity for early disease detection and rapid response.

    ... But still not sufficient

    ... It is necessary to continue with the 3Cs and support to where it is needed.

Slide 13

Challenges to be met

  • Countries’ capacities may be strengthened but such capacities may not be maintained

    - Staff
    - Budget

  • Information system: not existing, or existing but not working

  • Sharing virus samples:

    - Approval
    - Logistics

  • Preparedness for emergency response in non-affected should be considered as important as control of AI in affected countries

Slide 14

Thank you

Eradicating animal influenza viruses at their source
Presented by Christianne J.M. Bruschke
(OIE Scientific and Technical Department, Paris, France)

Slide 1

Dr. Christianne J.M. Bruschke,
Dr. A. Schudel
OIE Scientific and Technical Department,
Paris, France

Eradicating Animal Influenza Viruses at their Source

The FAO-ACPHA/OIE regional avian influenza
economic assessment workshop
26-29 September 2005 Bali

Slide 2

Outline of the Presentation

  • Why eradication at the source?

  • OIE International Standards

  • Zoning and compartmentalisation


Slide 3

Control of High Pathogenic AI at the animal source

  • Virus reservoir provides risk for pandemic

  • Elimination of the virus at the source of eminent importance

  • Animal health issues must have highest priority in combating the AI crisis

Slide 4

A Realistic Goal

  • Stepwise and phased disease control program for each country

  • Short, medium and long term frame

  • Progressively shift the majority of infected countries to "freedom from infection in defined compartments"

  • Ensure that free countries remain free

Slide 5

Critical issues for Avian Influenza control

  • Early warning, detection and response

  • Standards for

    - disease/infection detection
    - disease/infection prevention
    - animal movements and trade
    - animal and virus destruction
    - production and use of vaccination

  • Collaboration of OIE, FAO and WHO

Slide 6

The OIE early warning system

Slide 7

Outbreaks of Avian influenza in Asia (type H5)
(as of 1 September 2005)

Slide 8

OIE International Standards for Avian Influenza

  • Terrestrial Animal Health Code - mammals, birds and bees

    - Chapter 2.7.12
    - Appendix 3.8.9

  • Manual of Diagnostic Tests and Vaccines for Terrestrial Animals

  • Available at

Slide 9

Why standards necessary

  • international public good

  • safety of international trade

    - fewer disease outbreaks

  • harmonisation of national legislation and control measures

    - fewer unjustified restrictions

  • fairer trade

    - benefits to developing countries

Slide 10

Terrestrial Animal Health Code

  • To avoid introduction of pathogens without using unjustified sanitary barriers

  • Gives trading recommendations to the Chief Veterinary Officers of the OIE Member Countries

  • Provides guidelines for disease surveillance

Slide 11

Update chapter 2.7.12 on Avian Influenza

  • Update Chapter, taking most recent scientific findings into consideration (2004)

  • Development of specific risk-based recommendations for most important commodities being traded

  • Differentiate restrictions between HPAI and LPAI to encourage transparent reporting

Slide 12

Recent events:

  • Expert ad hoc group on pathogenesis and transmission (November 2004)

  • Expert ad hoc group on epidemiology and surveillance (November 2004)

  • Terrestrial Animal Health Standards Commission (January 2005)

Slide 13

Avian Influenza (Ch. 2.7.12)

  • Definition

    - Poultry
    - HPAI free
    - NAI free, free establishment

  • Commodity trading recommendations

  • Compartmentalization

  • Surveillance (with and without vaccination)

    - Clinical
    - Virological
    - Serological

Slide 14

Notifiable avian influenza (NAI): is defined as an infection of poultry caused by any influenza A virus of the H5 or H7 subtypes or by any AI virus with an intravenous pathogenicity index (IVPI) greater than 1.2 or


Slide 15

NAI viruses can be divided into highly pathogenic notifiable avian influenza (HPNAI) and low pathogenic notifiable avian influenza (LPNAI)

Slide 16

HPNAI viruses have an IVPI in 6-week-old chickens greater than 1.2 or, cause at least 75% mortality in 4 to 8 week old chickens infected intravenously.

Slide 17

H5 and H7 viruses which do not have an IVPI of greater than 1.2 or cause less than 75% mortality in an intravenous lethality test should be sequenced to determine HPNAI isolates.

Slide 18

LPNAI are all influenza A viruses of H5 and H7 subtype that are not HPNAI viruses.

Slide 19

Poultry is defined as ‘all birds reared or kept in captivity for the production of meat or eggs for consumption, for the production of other commercial products, for restocking supplies of game, or for breeding these categories of birds’.

Slide 20

NAI status (Ch. 2.7.12)

  • The NAI status of a country, zone or compartment

    - HPAI free
    - HPAI infected
    - NAI free zone or compartment

  • Guidelines for trade of poultry and poultry products

Slide 21

Guidelines for Surveillance (app. 3.8.9)

  • Defines principles and provides a guide for Disease Surveillance

  • To seek recognition for a declared free NAI status

    - Maintenance or following outbreak
    - With or without vaccination
    - Application can be made for a country, zone or compartment

Slide 22

Surveillance Strategies

  • Random surveillance

    - Statistically based surveys
    - Serological testing followed by virological methods for confirmation

  • Targeted surveillance

    - Aimed at high risk groups
    - Serological and virological methods concurrently

Slide 23

Surveillance Strategies

  • Detection of clinical signs of NAI at the flock level

    - Important for HPNAI

  • Strategies

    - Clinical followed by serological surveillance or
    - Serological followed by clinical surveillance

Slide 24

Surveillance: Vaccinated flocks

  • Strategy dependent on the type of vaccine used

    - Inactivated whole AIV
    - DIVA: Hemagglutinin expression-based vaccines

  • Sentinel birds

    - Unvaccinated, permanently identifiable

Slide 25

OIE Manual of Diagnostic Tests and Vaccines for Terrestrial Animals

  • The Manual is a companion volume of the Code.

  • The purpose is to facilitate international trade in animals and animal products by describing internationally agreed upon laboratory methods for diagnosis and requirements for the production and control of vaccines.

Slide 26

Diagnostic Techniques

  • Identification of the Agent

  • Assessment of pathogenicity

  • Serology

  • Developing techniques

  • new interpretation and definition of notifiable AI

Slide 27


  • Existing standard

    - based on traditional inactivated vaccine
    - use of subtypes homologous to the outbreak, but normally low pathogenicity subtypes

  • new DIVA strategies can reduce mass culling

  • recombinant vaccines have a place

Slide 28

Animal Welfare

  • Animal welfare is included in the strategic plan of OIE

  • Animal welfare concerns

    - Guidelines on killing for disease control
    - Guidelines on slaughter, including religious
    - Guidelines on land transport

Slide 29

Zoning and Compartmentalisation (Ch 1.3.5)

  • To establish and maintain a subpopulation with a different health status within the national borders

  • Zoning: separation by natural or artificial geographical barriers

  • Compartmentalisation: separation via a biosecurity management system

Slide 30

Zoning and Compartmentalisation Benefits

  • Allows a stepwise approach to disease control in a country

  • May encourage the efficient use of resources

  • May allow safe trade in certain commodities due to functional separation

Slide 31

Principles for definition of a zone or compartment

  • Establishment by the veterinary administration

  • The animals belonging to the subpopulation should be clearly recognisable

  • The measures necessary to preserve distinct health status must be defined and appropriate to the disease

Slide 32

Sequence of steps in definition of zone or compartment

  • Exporting country

    - defines the zone or compartment
    - Identifies animals and has a valid traceability in place
    - Defines the standard operating procedures (eg biosecurity manual)
    - Provides the information to the importing country

Slide 33

Sequence of steps in definition of zone or compartment

  • Importing country determines whether it accepts the zone or compartment

    - Evaluates the Vet Services of the exporting country
    - Makes risk assessment
    - Takes own health status into account
    - Takes OIE standards into account

Slide 34

Sequence of steps in definition of zone or compartment

  • Importing country

    - Rejects
    - Requests further information
    - Recognises

  • Formal agreement between both parties

Slide 35

Factors for the evaluation of the zone or compartment

  • Definition

  • Epidemiologic separation from potential sources of infection (physical or biosecurity)

  • Standard operating procedures in place

  • Permanent supervision and assessment by Veterinary Services

  • Surveillance for the agent/disease

  • Diagnostic capabilities

  • Notification and emergency response

Slide 36

OIE/FAO Network for Avian
Influenza (2005)


Slide 37

OIE/FAO Network for Avian influenza OFFLU

  • To offer veterinary expertise to Member Countries to assist in the control of AI

  • To develop research on avian influenza (AI)

  • To collaborate with the WHO Influenza Network on issues relating to the animal-human interface

Slide 38

Structure OFFLU

  • Steering Committee

  • Secretariat:

    - Dr I. Capua, OIE reference laboratory Padova

  • Scientific Committee:

    - experts with international repute with proven lab expertise and/or field experience

  • Team of Scientific Collaborators

    - Scientists having first hand experience, national and regional expertise in lab work, epidemiology or field control

Slide 39

Scientific Collaborators

  • Invited to participate from as wide a field as possible

  • Terms of Reference

    - Liaise with Sc.C. to advise in management, control and eradication of AI
    - Promote the collection of strains for identification
    - Assist in training for lab diagnosis and field surveillance
    - Promote linkages between diagnostic labs in poor countries with industrialized countries

Slide 40

OFFLU: main priorities

  • Exchange of virus isolates and sequence data among reference and diagnostic labs

  • Exchange of Scientific information

  • Communication with member countries and international organisations

  • Provide advice and expertise to infected countries

  • Monitor vaccine trials

Slide 41


  • Depends commitment of collaborators

  • Financial resources

  • Ambitious program

Slide 42

World Organisation for Animal Health
created in 1924 in Paris

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