American medicinal plants, particularly those of Mexico, attracted attention immediately after the discovery and it was with these plants that scientific studies of the New World began. For European medicine, which was still at a medieval stage, the discovery of the purgative properties of Ipomaea jalapa, the Michoacan root, was evidently sufficient reason to justify Dr Francisco Hernández' (1517- 1587) expedition to New Spain. Numerous plants were included in the European pharmacopoeia and some of them, despite their synthetic substitutes, are still of worldwide importance; for example, the genera Cinchona, Dioscorea, Ipecacuanha and Smilax. The first three of these have been cultivated but a large proportion of their supply for consumption is gathered. Most medicinal substances are obtained from the wild plants and, in many cases, it is not certain if they have the properties attributed to them. Bordering on the medicinal area are the hallucinogenic plants, distributed among numerous higher plant families; for instance, the Cactaceae (Lophophora, Tricholerus), the Leguminosae (Adenunthera, Erythrina), the Myristicaceae (Virola) or fungi (Psylocibe).
TABLE 1 Cultivated plants originating in the New World, and their probable distribution at the time of the discovery
| Family and species | Common names | Distribution |
| CEREALS AND OTHER GRAINS | ||
| Amaranthaceae | ||
| Amaranthus caudatus | Love-lies-bleeding, cat-tail, Inca wheat, tumbleweed achis, achita, ataco, coima, kiwicha, sangorache | Ecuador, Argentina |
| Amaranthus cruentus | Chian, alegria | United States (New Mexico), Guatemala |
| Amaranthus hypochondriacus | Prince's feather, huautli, alegria | United States (New Mexico), Guatemala |
| Gramineae | ||
| Zea mays | Maize | Canada, Argentina |
| Bromus mango | Brome(grass), wild rye | Chile |
| Elymus sp. | Teca | Chile |
| Compositae | ||
| Iva annua | - | United States |
| Chenopodiaceae | ||
| Chenopodium pallidicaule | Canihua, qañiwa, cañahua | Peru, Bolivia |
| Chenopodium quinoa | Quinoa, quinua, suba | Colombia, Chile |
| Chenopodium sp. (att. buschianum) | - | United States |
| Martyniaceae | ||
| Proboscidea parviflora | New Mexico devil's claw | United States |
| SPICES AND CONDIMENTS | ||
| Apocynaceae | ||
| Fernaldia pandurata | Loroco | El Salvador |
| Bombacaceae | ||
| Quararibea funebris | Cacaoxochitl | Mexico |
| Cyperaceae | ||
| Cyperus sp. | Flatsedge, pripreoca | Amazon region |
| Compositae | ||
| Eupatorium ayapana | Ayapana | Amazon region |
| Porophyllum ruderale | Poreleaf, quiliquiña | Bolivia |
| Spitanthes oleracea | ||
| (Spilanthes acmella var. oleracea) | Pará cress, berro | Peru |
| Tagetes graveolens | Huacatay | Peru Bolivia |
| Tagetes mandoni | Huacatay, suico | Peru Bolivia |
| Myrtaceae | ||
| Pimenta dioica | Allspice, pimento, | Mexico, Guatemala, Antilles |
| (Pimenta officinalis) | Jamaica pepper | |
| Orchidaceae | ||
| Vanilla planifolia | Vanilla | Mexico |
| Chenopodiaceae | ||
| Chenopodium ambrosioides | Wormseed, Mexican tea, epazote | Mexico, Peru |
| Solanaceae | ||
| Capsicum annuum | Pepper, chili, pimento, bird pepper | United States, northern South America |
| Capsicum baccatum | South America | |
| Capsicum chinese | Northern South America | |
| Capsicum frutescens | Mesoamerica | |
| Capsicum pubescens | Ecuador, Bolivia | |
| Umbelliferae | ||
| Eryngium foetidum | Mountain coriander, eryngo | Mesoamerica, Antilles |
| STIMULANTS | ||
| Agavaceae | ||
| Agave cocui | Cocuy | Venezuela |
| Agave mapisiga | - | Mexico |
| Agave salmiana | Pulque, aguamiel | Mesoamerica |
| Aquifoliaceae | ||
| Ilex paraguariensis | Mate, Brazilian tea, Paraguay tea | Paraguay, Argentina |
| Erythroxilaceae | ||
| Erythroxylum coca | Coca, ipadú | Northern and central South America |
| Erythroxylum novo-granatense | Peruvian cocaine | Western South America |
| Sterculiaceae | ||
| Theobroma angustifolium | Monkey chocolate | Mesoamerica |
| Theobroma cacao | Cocoa, cacao | Mesoamerica |
| Sapindaceae | ||
| Paullinia cupana | Guarana | Brazil |
| Paullinia yoco | Yoco | Colombia, Ecuador |
| FIBRES | ||
| Agavaceae | ||
| Agave angustifolia var. letonae | Salvador henquen, maguey,letona agave | El Salvador |
| Agave cantala | Cantala, Manila maguey, Bombay aloe | Mexico |
| Agave fourcroydes | Henequen, henequen agave | Mexico |
| Agave sisalana | Sisal, Bahama
hemp, true sisal, sisal agave, green agave |
Mexico |
| Furcraea andina | Furcrea, chuchao, cabuya | Ecuador, Peru |
| Furcraea cabuya | Cabuya, pita, furcrea | Costa Rica, Colombia |
| Furcraea foetida | ||
| (Furcraea gigantea) | Piteira furcrea, giant lily, Mauritius Hemp | Colombia, Venezuela |
| Furcraea humboldtiana | Cocuiza, Humboldt furcrea | Colombia, Venezuela |
| Furcraea macrophylla | Fique, fique furcrea | Colombia |
| Bromeliaceae | ||
| Aechmea magdalenae | Pita floja | Mexico, Venezuela, Ecuador |
| Ananas erectifolius | Carua | Brazil |
| Neoglaziovia variegate | Caroa, carua | Brazil |
| Cyclanthaceae | ||
| Carludovica palmata | Toquilla, Panama hat palm | Guatemala, Peru, Brazil |
| Malvaceae | ||
| Gossypium barbadense | Sea island cotton, West Indian cotton | Northern South America, Guatemala, Belize, Antilles |
| Gossypium hirsutum | Upland cotton, hairy cotton | Mesoamerica, Antilles |
| Palmae | ||
| Attalea funifera | Bahia piassava, piassalba, coquilla, piasava, piasaba | Brazil |