Pesticide Residues in Food - 1996. Report Sponsored Jointly by FAO and WHO. (FAO Plant Production and Protection Paper - 140)













Table of Contents


Report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Expert Group on Pesticide Residues

Rome, Italy
16-25 September 1996

WORLD HEALTH ORGANIZATION

FAO - Food and Agriculture Organization of the United Nations
Rome, 1997

Monographs containing summaries or residue data and toxicological data considered at the 1996 JMPR, together with recommendations, are available upon request from FAO or WHO under the title:

Pesticide residues in food - 1996
Evaluations 1996
Part I: Residues

FAO Plant Production and Protection Paper
and
Part II: Toxicology
WHO

The designations employed and the presentation of material in this publication do not imply the expression of any opinion whatsoever on the part of the Food and Agriculture Organization of the United Nations concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries.

This report contains the collective views of two international groups of experts and does not necessarily represent the decisions or the stated policy of the Food and Agriculture Organization of the United Nations or of the World Health Organization.

INTERNATIONAL PROGRAMME ON CHEMICAL SAFETY

The preparatory work for the toxicological evaluations of pesticide residues carried out by the WHO Expert Group on Pesticide Residues for consideration by the FAO/WHO Joint Meeting on Pesticide Residues in Food and the Environment is actively supported by the International Programme on Chemical Safety (IPCS). IPCS is a joint venture of the United Nations Environment Programme, the International Labour Organization and the World Health Organization. One of the main objectives of IPCS is to carry out and disseminate evaluations of the effects of chemicals on human health and the quality of the environment.

M-84
ISBN 92-5-103932-1

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying or otherwise, without the prior permission of the copyright owner. Applications for such permission, with a statement of the purpose and extent of the reproduction, should be addressed to the Director, Information Division, Food and Agriculture Organization of the United Nations, Viale delle Terme di Caracalla, 00100 Rome, Italy.

© FAO 1997

1996 JOINT MEETING OF THE FAO PANEL OF EXPERTS ON PESTICIDE RESIDUES IN FOOD AND THE ENVIRONMENT AND THE WHO CORE ASSESSMENT GROUP

Rome. 16-25 September 1996

This electronic document has been scanned using optical character recognition (OCR) software and careful manual recorrection. Even if the quality of digitalisation is high, the FAO declines all responsibility for any discrepancies that may exist between the present document and its original printed version.


Table of Contents


PARTICIPANTS

ABBREVIATIONS WHICH MAY BE USED

1. INTRODUCTION

2. GENERAL CONSIDERATIONS

2.1 Modifications to the agenda
2.2 Prediction of dietary intake

2.2.1 Revised guidelines for predicting the dietary intake of pesticide residues
2.2.2 Calculation of dietary intake of pesticide residues
2.2.3 Estimation of supervised trials median residue levels
2.2.4 Example of STMR estimation: Parathion-methyl

2.3 Relationship between Codex Maximum Residue Limits (MRLs) for pesticide residues, good agricultural practice (GAP), and food safety
2.4 Estimation of extraneous residue limits (ERLs)
2.5 Estimation of group maximum residue levels
2.6 Use by the WHO Core Assessment Group of national evaluations of studies
2.7 Interactions of pesticides
2.8 Environmental Core Assessment Group

3. SPECIFIC PROBLEMS

3.1 Definition of residues of fat-soluble compounds

4. EVALUATION OF DATA FOR ACCEPTABLE DAILY INTAKE FOR HUMANS, SUPERVISED TRIALS MEDIAN RESIDUE LEVELS AND MAXIMUM RESIDUE LIMITS

4.1 Acephate (095)
4.2 Aldicarb (117)
4.3 Bifenthrin (178)
4.4 Carbaryl (008)
4.5 Carbofuran (096)
4.6 Chlorfenvinphos (014)
4.7 2,4-D (020)
4.8 DDT (021)
4.9 Diazinon (022)
4.10 Dimethoate, omethoate, and formothion (027, 055, 042)
4.11 Disulfoton (074)
4.12 Dithiocarbamates (105)
4.13 Fenarimol (192)
4.14 Ferbam (Dithiocarbamates, 105)
4.15 Flumethrin (195)
4.16 Haloxyfop (194)
4.17 Maleic hydrazide (102)
4.18 Methamidophos (100)
4.19 Mevinphos (053)
4.20 Phorate (112)
4.21 Propoxur (075)
4.22 Tebufenozide (196)
4.23 Teflubenzuron (190)
4.24 Thiram (Dithiocarbamates, 105)
4.25 Ziram (Dithiocarbamates, 105)

5. RECOMMENDATIONS

6. FUTURE WORK

6.1 1997 Meeting (tentative)
6.2 1998 Meeting (tentative)

7. REFERENCES

CORRECTIONS TO REPORT OF 1995 JMPR

ANNEX I: ADIs, MRLs and STMRs

ANNEX II Index of reports and evaluations

ANNEX III - Intake predictions

ANNEX IV: Report of Workshop on Data Evaluation