Corn MON 810 with resistance to Lepidopteran pests are produced through introduction of the cry1Ab gene from Bacillus thuringiensis subsp. kurstaki. The cry1Ab sequence encodes for the production of a Bt insect toxin.
Corn NK 603 with tolerance to the family of Roundup® herbicides are produced through introduction of the cp4 epsps gene from Agrobacterium sp. Strain CP4. The cp4 epsps sequence encodes for the production of the naturally occurring 5-enolpyruvylshikimate-3-phosphate synthase.
Inbred line, MON 810, was crossed with inbred line, NK 603, resulting in the combined trait product MON 810 x NK 603 with resistance to insects and tolerance to the herbicide glyphosate.
Date of authorization:
Scope of authorization:
Food and feed
Links to the information on the same product in other databases maintained by relevant international organizations, as appropriate. (We recommend providing links to only those databases to which your country has officially contributed.):
Summary of the safety assessment:
Monsanto Philippines, Inc. has filed an application with attached technical dossiers to the Bureau of Plant Industry (BPI) for a biosafety notifications for direct use as food, feed and for processing under Department of Agriculture (DA) Administrative Order (AO) No. 8 Part 5 for Combined trait product corn: MON810 x NK603 which has been genetically modified for insect resistance and herbicide tolerance.
A safety assessment of combined trait product corn: MON 810 x NK 603 was conducted as per AO 8 Series of 2002. The focus of risk assessment is the gene interactions between the two transgenes.
Review of results of evaluation by the BPI Biotech Core Team in consultation with DA-Biotechnology Advisory Team (DA-BAT) completed the approval process.
Where detection method protocols and appropriate reference material (non-viable, or in certain circumstances, viable) suitable for low-level situation may be obtained:
Relevant links to documents and information prepared by the competent authority responsible for the safety assessment:
Gene stacking in plants can be conferred either through genetic engineering or conventional breeding
A full risk assessment as to food and feed or for processing shall be conducted to plant products carrying stacked genes conferred through genetic engineering or conventional breeding, where the individual traits have no prior approval for direct use as food and feed or processing from the Bureau of Plant Industry (BPI)
A desktop or documentary risk assessment on the possible or expected interactions between the genes shall be conducted for stacked gene products with multiple traits conferred through conventional breeding and individual events granted prior approval by the Bureau of Plant Industry.
Contact details of the competent authority(s) responsible for the safety assessment and the product applicant:
Bureau of Plant Industry 692 San Andres St, Malate, Manila 1004