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Online Edition: "Specifications for Flavourings"

Flavouring beta-Caryophyllene oxide
Synonym(s) Caryophyllene epoxide;Caryophyllene oxide
Latest JECFA evaluation 2020 (Session 89)
Status of specification Full
Chemical name 4,5-Epoxy-4,12,12-trimethyl-8-methylene-bicyclo(8.2.0)dodecane
JECFA number 1575
CAS number 1139-30-6
FEMA number 4085
COE number
FLAVIS number 16.043
Molecular weight 220.35
Chemical formula C15H24O
Physical form/odour Colourless solid; Sweet fruity aroma
Solubility Insoluble in water; Soluble in fat
Solubility in ethanol Soluble
Boiling point (°C)
Assay min % 95% (sum of isomers)
Acid value max
Refractive index
Specific gravity
Other requirements mp: 55-63°; Isomers: 84-89% (1R, 4R, 6R, 10S) (CAS No. 1139-30-6); 7-9% (1R, 4R, 6S, 10S) (CAS No. 60594-22-1); 0.3-2% (1R, 4S, 6S, 10S) (CAS No. 103475-43-0); 1-2% Humulene-1,2-epoxide (CAS No. 19888-34-7)