Pesticide Registration Toolkit

Terms and definitions L

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Limit of determination (LOD):

Lowest concentration of a pesticide residue or contaminant that can be identified and quantitatively measured in a specified food, agricultural commodity or animal feed with an acceptable degree of certainty by a regulatory method of analysis. [Source: JMPR]

Limit of quantification (LOQ):

Smallest concentration of the analyte that can be quantified. It is commonly defined as the minimum concentration of analyte in the test sample that can be determined with acceptable precision (repeatability) and accuracy under the stated conditions of the test. [Source: JMPR]

Limit test:

Acute toxicity test in which, if no ill-effects occur at a preselected maximum dose, no further testing at greater exposure levels is required. [Source: IUPAC]

Lowest-observed-adverse-effect level (LOAEL):

Lowest concentration or amount of a substance (dose), found by experiment or observation, that causes an adverse effect on morphology, functional capacity, growth, development, or life span of a target organism distinguishable from normal (control) organisms of the same species and strain under defined conditions of exposure. [Source: IUPAC]