The Karamoja region, in North East Uganda, is one of the least developed regions of the country, and is highly vulnerable to resource-based conflict and climate change variability. Addressing food insecurity of vulnerable people is a major challenge in the region. Measuring resilience provides more informed policies for withstanding shocks. For this reason, the Food and Agriculture Organization of the United Nations (FAO), the United Nations Children's Fund (UNICEF) and the World Food Programme (WFP) developed a Joint Resilience Strategy (JRS) launched in January 2016. The JRS is based on four main pillars: strengthening the productive sector to increase household income and food security; improving basic social services; establishing predictable safety nets that address most vulnerable people’s basic needs; and strengthening disaster risk management. The present policy brief summarize the main findings and policy reccomendations of the analysis.