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Food safety aspects of cell-based food

Background document three – Regulatory frameworks









FAO. 2022. Food safety aspects of cell-based food. Background document three – Regulatory frameworks. Rome.



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    Booklet
    Cell-based food and precision fermentation – Products, safety and the future role
    Stakeholder roundtable meeting report, Shanghai, China, 6 November 2023
    2024
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    As the global demand for proteins and specific nutrients grows, many people are looking into opportunities to expand the scope of diverse and sustainable sources of such nutrients. Food safety is one of the prominent key issues to ascertain before such products go into the market, and various competent authorities are working to identify and address potential food safety issues and their implications. After the first stakeholder meeting on cell-based food organized by the Food and Agriculture Organization of the United Nations (FAO) in collaboration with the Government of Israel, many experts suggested that FAO maintain such dialogues to regularly update the knowledge of this fast-improving technology. This led to the stakeholder meeting organized by FAO jointly with the Government of China in November 2023, which considered precision fermentation besides cell-based food. The present report summarized the results of the meeting attended by a total of 55 participants in Shanghai, China on 6 November 2023. The meeting provided a snapshot of the state of development of these particular technologies and the industry in 2023. As an increasing number of countries are reviewing the regulatory applications, valid examples of how to assess product safety have become available. All participants recognized that open discussions between stakeholders and regulators are key when it comes to clarifying important aspects of food safety, and that supporting the relevant scientific innovations is vital for achieving the overall food security goals and sustainable food production for the future.
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    Booklet
    Food safety aspects of cell-based food
    Background document two - Generic production process
    2022
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    Cell-based food production encompasses a variety of techniques and technologies that enable the production of animal proteins from in vitro grown animal or microbial cells. Most of them are currently under development and some are ready to be scaled up for commercialization. Cell-based food production can aim at producing a wide variety of products with different animal proteins from beef, pork, poultry, fish, shellfish and many others, including dairy and egg products. Therefore, it is not optimal to develop a detailed overview of the production process of cell-based food as a whole, but a generic understanding of a high-level process for cell-based food production can be illustrated. By having such a basic understanding, potential hazard identification, the first step in food safety assessment, can be initiated. To ensure the food safety of cell-based food products, it is important for the food safety competent authorities to identify specific potential hazards for effective national food control systems. The scientific literature review was conducted to provide an overview of the cell-based food production processes currently being practised. The document also illustrates a limited number of the key potential hazards that have been identified through the review of the available literature, although further work is necessary to provide a comprehensive list of food safety hazards. The document serves as a basis to initiate the first step of the appropriate food safety assessment, which will eventually support both cell-based food developers and regulators worldwide in making informed decisions on setting up food safety assurance systems.
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    Booklet
    Food safety aspects of cell-based food
    Report of the publication launch webinar, 7 April 2023
    2024
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    The Food and Agriculture Organization of the United Nations (FAO) and the World Health Organization (WHO) held a webinar to launch the publication entitled “Food safety aspects of cell-based food” published in April 2023. The webinar was attended by a total of 1 015 participants from more than 75 countries.Cell-based food production involves culturing animal cells in a controlled environment to produce various types of food products. As this technology is constantly evolving, it is important for food safety authorities to keep up with science in order to understand how the products are developed and what food safety considerations are relevant when taking regulatory actions. The webinar included a lecture on the subject by the chairperson of the FAO-led expert consultation, who introduced the contents of the FAO/WHO publication and presented the results of the first global food safety hazard identification of cell-based food. Experts reported that most of the hazards identified were common to conventional food products and emphasized the importance for food safety competent authorities to focus on the materials, inputs and equipment specific to cell-based food production.Two regulatory experts from the governments of Singapore and Qatar took part in the webinar to introduce the case studies of their respective countries’ regulatory frameworks. These case studies illustrated the commonly held idea that a food safety assessment is one of the first steps within the regulatory frameworks presented in the case studies, despite the fact that other elements within the framework may be different. This was borne out by subsequent panel discussions with six panellists from Argentina, Australia, Qatar, Singapore, the United States of America and Zambia who all concurred that a food safety assessment provides a crucial starting point. All panellists emphasized the importance of the FAO/WHO publication as an invaluable source of technical information in this regard, particularly as it lists potential hazards that regulators can draw on. The publication also contains vital information on nomenclature and useful advice on ways to effectively communicate this topic to the public.The webinar included an interactive discussion session with the participants, during which basic food safety and regulatory questions were raised. FAO and WHO concluded the webinar with the offer to provide technical assistance to those countries in need of it.

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