In the Mediterranean area, precise and accurate data regarding food waste and losses should be enhanced, especially in a context where the food security of the region’s countries is fragile and the sustainability of development is threatened. During the 10th meeting of the CIHEAM member states agriculture ministers, the food waste issue was strongly emphasised. Considering the importance of the topic, the CIHEAM’s Governing Board has decided to devote the 2016 edition of the Regional Report Mediterra to wastes (natural resources, food and knowledge) and the ways to combat scarcities. The CIHEAM has already launched several research and technical development activities dealing with the issue. Beyond the support given to the national and local authorities of our member countries, the waste issue will probably become a key field of cooperation with regional and international organizations operating in the Mediterranean, especially the FAO that considers this issue as one the major challenges in North Africa and Middle East.