Programmes to reduce emissions from deforestation and ecosystem degradation, such as REDD+ and other forestry incentive programmes, including Payment for Environmental Services (PES), could represent an opportunity to strengthen processes of conservation, sustainable usage and poverty reduction in the Mesoamerican region, particularly in indigenous territories and communities. Analysing the context of such initiatives and how they are interlinked is relevant to understanding how these multipurpose programmes can achieve their objectives in the light of recent developments in the recognition of indigenous peoples’ rights over land tenure and natural resources in the region. Examining these contexts and their linkages in countries such as Costa Rica, Guatemala, Honduras, Mexico, Nicaragua and Panama, where there are considerable forest areas with significant indigenous populations, is the aim of this study.