Food safety and quality
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OECD Unique Identifier details

BCS-BNØ12-7 x ACS-BNØØ3-6
Commodity: Canola / Oilseed rape / Rape Seed
Traits: Herbicide tolerance
Singapore
Name of product applicant: BASF
Summary of application:

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Date of authorization: 16/04/2021
Scope of authorization: Food and feed
Links to the information on the same product in other databases maintained by relevant international organizations, as appropriate. (We recommend providing links to only those databases to which your country has officially contributed.):
Summary of the safety assessment (food safety):
MS11 x RF3 (BCS-BNØ12-7 x ACS-BNØØ3-6) oilseed rape was produced by conventional breeding of MS11 and RF3. All plants are fully fertile hybrids and express the PAT/bar protein which confers tolerance to glufosinate-ammonium. MS11 is intended to replace MS8 in MS8 x RF3. Oilseed rape MS8 x RF3 has been approved in Singapore for feed, feed and processing uses. Like MS8, MS11 is male sterile and glufosinate-ammonium resistant. The only difference is that MS11 contains the barstar gene that results in low level expression of the barstar protein. This gene is intended to improve transformation efficiency; it has no effect on the male sterile phenotype of MS11. MS11 was produced by Agrobacterium-mediated transformation using vector pTCO113 containing a barnase-barstar gene cassette to confer male sterility and a bar gene cassette to confer tolerance to the herbicide glufosinate-ammonium. RF3 was produced by Agrobacterium-mediated transformation using vector pTHW118 containing barstar gene cassette to confer fertility restoration and a bar gene cassette to confer tolerance to the herbicide glufosinate-ammonium. The inserted transgenic sequence of MS11 consists of one copy of the transforming T-DNA and that the transferred DNA in the plant corresponds to original DNA configuration of the pTCO113 plasmid. the RF3 transgenic insert consists of one partial copy of the T-DNA, where only part of the Pta29 promoter was inserted, flanked by another partial copy in an inverted orientation, which includes a complete barstar gene cassette and a part of the PssuAt promoter. The transgenic plants have been shown to be identical to untransformed control plants for all biological features except for the predicted effects of the inserted genes. The lines were phenotypically and genetically stable. The level of gene expression has been determined. No other than the intended functions were expressed. The proteins expressed are non-toxic and non-allergenic. A compositional analysis showed that the nutrient composition of MS11 x RF3 oilseed rape is similar to that of the conventional counterpart. MS11 x RF3 is considered to be as safe as food derived from conventional potato varieties.
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Organization/agency name (Full name):
Agri-Food & Veterinary Authority of Singapore (AVA)
Contact person name:
Dr Wong Kwok Onn
Website:
Physical full address:
52 Jurong Gateway Road, #14-01, Singapore 608550
Phone number:
(65)68052895
Fax number:
Country introduction:

The Singapore Food Agency (SFA) is a Statutory Board established under the Ministry of Sustainability and the Environment (MSE) to oversee food safety and security. SFA’s mission is to ensure and secure a supply of safe food.  SFA adopts a risk-based approach to food safety. Foods with foodborne hazards that may pose potential food safety risks to consumers are subjected to more stringent checks, regardless of their country of origin. SFA has in place an integrated system to ensure that both imported and domestically produced foods are safe for consumption.  The system comprises control measures such as source accreditation, inspection and surveillance of food, laboratory analysis, food legislation and recall of food products, which safeguard food safety from farm to fork.

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Relevant documents
Stacked events:

More information on the guidelines for the safety assessment of stacked events can be found on GMAC’s website:

http://www.gmac.sg/Index_Singapore_Guidelines_on_the_Release_of_Agriculture_Related_GMOs.html

Contact details of the competent authority(s) responsible for the safety assessment and the product applicant:

Singapore Food Agency (SFA)