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Inocuidad y calidad de los alimentos
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Edición en línea: "Residuos en drogas veterinarias"

Ayuda en línea   Terminology

Esta base de datos contiene la información más reciente sobre los niveles máximos de residuos en drogas veterinarias según lo recomendado por JECFA. Todas las monografías publicadas en la FAO sobre Alimentación y Nutrición, Papeles 41, son accesibles en formato electrónico. Estas monografías están sólo disponibles en inglés aunque algunas partes de la base de datos, como la página de preguntas y también una información básica se puede encontrar en árabe, chino, español, francés e inglés.

Medicamento veterinario Streptomycin
La clase funcional Antimicrobial agent
Ultima evaluación 2002
Reunión de JECFA 58
IDA 0-50 µg/kg bw
Estatus de IDA Full
Monografías de residuos  
41-7-dihydrostreptomycin_streptomycin.pdf
41-10-dihydrostreptomycin_streptomycin.pdf
41-12-dihydrostreptomycin_streptomycin.pdf
41-14-streptomycins.pdf
Definición del residuo Sum of dihydrostreptomycin and streptomycin
Límites máximos para residuos
(LMR) recomendados
CattleFat600 µg/kgF
CattleKidney1000 µg/kgF
CattleLiver600 µg/kgF
CattleMilk200 µg/kgF
CattleMuscle600 µg/kgF
ChickenFat600 µg/kgF
ChickenKidney1000 µg/kgF
ChickenLiver600 µg/kgF
ChickenMuscle600 µg/kgF
PigFat600 µg/kgF
PigKidney1000 µg/kgF
PigLiver600 µg/kgF
PigMuscle600 µg/kgF
SheepFat600 µg/kgF
SheepKidney1000 µg/kgF
SheepLiver600 µg/kgF
SheepMilk200 µg/kgF
SheepMuscle600 µg/kgF
Otras observaciones See dihydrostreptomycin/streptomycin
El resumen de la evaluación At its present meeting, the Committee considered that the sponsors had provided satisfactory answers to all of its requests made at the forty-third meeting. It therefore decided to delete the temporary status of the MRLs, except that for milk. The MRLs for muscle, liver and fat were raised to 600 µg/kg, to take into account the twofold higher LOQ of the bioassay method compared with the HPLC method. The recommended MRL for kidney was 1000 µg/kg in cattle, pigs, sheep and chickens. The MRLs were expressed as the sum of the concentrations of dihydrostreptomycin and streptomycin.
From the above MRL values, the theoretical maximum daily intake of dihydrostreptomycin and streptomycin residues is 620 µg (equivalent to 21% of the maximum ADI), based on a daily food intake of 300 g of muscle, 100 g of liver, 50g each of liver and fat, and 1.5 kg of milk. If milk is excluded, the theoretical maximum daily intake is 320 µg or 11% of the ADI.
TRS 893.
The submitted HPLC method with fluorescence detection met the performance criteria for the analysis of dihydrostreptomycin and streptomycin in cow's and sheep's milk and was judged to be acceptable for routine monitoring of milk samples.
Although the study of residue depletion in sheep's milk had not been requested by the Committee, it provided the data needed to recommend an MRL for the combined residues of dihydrostreptomycin and streptomycin in sheep's milk. Therefore, the Committee recommended that the temporary designation for cow's milk of 200 µg/kg, measured as the combined residuesof dihydrostreptomycin and streptomycin, be removed and that theMRL of 200 µg/kg be extended to sheeps milk for the combined residues'of dihydrostreptomycin and streptomycin.
TRS 911