Edición en línea: "Residuos en drogas veterinarias"

Ayuda en línea Terminology

Esta base de datos contiene la información más reciente sobre los niveles máximos de residuos en drogas veterinarias según lo recomendado por JECFA. Todas las monografías publicadas en la FAO sobre Alimentación y Nutrición, Papeles 41, son accesibles en formato electrónico. Estas monografías están sólo disponibles en inglés aunque algunas partes de la base de datos, como la página de preguntas y también una información básica se puede encontrar en árabe, chino, español, francés e inglés.

Medicamento veterinario

Sulfadimidine

La clase funcional

Antimicrobial agent

Ultima evaluación

1994

Reunión de JECFA

IDA

0-50 µg/kg bw

Estatus de IDA

Full

Monografías de residuos

41-2-general_consideration_for_sulfamidine_and_sulfathiazole.pdf

41-2-sulfadimidine.pdf

Definición del residuo

Parent drug

Límites máximos para residuos
(LMR) recomendados

Cattle	Fat	100 µg/kg	F
Cattle	Kidney	100 µg/kg	F
Cattle	Liver	100 µg/kg	F
Cattle	Milk	25 µg/kg	F
Cattle	Muscle	100 µg/kg	F
Pig	Fat	100 µg/kg	F
Pig	Kidney	100 µg/kg	F
Pig	Liver	100 µg/kg	F
Pig	Muscle	100 µg/kg	F
Poultry	Fat	100 µg/kg	F
Poultry	Kidney	100 µg/kg	F
Poultry	Liver	100 µg/kg	F
Poultry	Muscle	100 µg/kg	F
Sheep	Fat	100 µg/kg	F
Sheep	Kidney	100 µg/kg	F
Sheep	Liver	100 µg/kg	F
Sheep	Muscle	100 µg/kg	F

Otras observaciones

El resumen de la evaluación

The Committee recognized that information on hypersensitivity reactions resulting from the ingestion of tissues containing sulfonamides would be extremely difficult, if not impossible, to obtain. In line with the previous evaluation, the Committee therefore recommended that the MRLs should be set as low as practicable possible in naccordance with Good Practice in the Use of Veterinary Drugs. In doing so, the Committee recognized that these concentrations would then be below the levels considered significant from the point of view of microbiological concern. On this basis, the Committee concluded that the MRLs for sulfadimidine should remain as recommended at its thirty-fourth meeting since methods are routinely available for national residue monitoring. The values recommended for cattle, sheep, pigs and poultry are 100 µg/kg as sulfadimidine in muscle, liver, kidney and fat. The recommended MRL for milk as sulfadimidine is 25 µg/l. With these MRLs, the theoretical maximum daily intake of sulfadimidine residues is 87.5 µg/day, which is considerably less than the maximum ADI of 3 mg for a 60 kg person. The residue data available for eggs indicate that compliance with current practices in egg production would result in very high concentrations of sulfadimidine in eggs. For this reason, the Committee considered that sulfadimidine should not be used in laying hens, and did not recommend an MRL for eggs.
TRS 851