Edición en línea: "Residuos en drogas veterinarias"

Ayuda en línea Terminology

Esta base de datos contiene la información más reciente sobre los niveles máximos de residuos en drogas veterinarias según lo recomendado por JECFA. Todas las monografías publicadas en la FAO sobre Alimentación y Nutrición, Papeles 41, son accesibles en formato electrónico. Estas monografías están sólo disponibles en inglés aunque algunas partes de la base de datos, como la página de preguntas y también una información básica se puede encontrar en árabe, chino, español, francés e inglés.

Medicamento veterinario

Eprinomectin

La clase funcional

Antiparasitic

Ultima evaluación

1998

Reunión de JECFA

IDA

0-10 µg/kg bw

Estatus de IDA

Full

Monografías de residuos

41-12-estradiol_17-beta_progesterone_testosterone.pdf

41-1-progesterone.pdf

Definición del residuo

Eprinomectin B1a

Límites máximos para residuos
(LMR) recomendados

Cattle	Fat	250 µg/kg	F
Cattle	Kidney	300 µg/kg	F
Cattle	Liver	2000 µg/kg	F
Cattle	Milk	20 µg/l	F
Cattle	Muscle	100 µg/kg	F

Otras observaciones

El resumen de la evaluación

In recommending MRLs for various tissue matrices, the Committee took the following factors into consideration:
- The drug is for use in dairy and beef cattle.
- The limits of quantification of the analytical methods are 1.0 µg/l and 2.0 µg/kg for milk and tissues, respectively.
- The marker residue is eprinomectin B1a.
- The marker residue is always the predominant residue in both tissues and milk. Eprinomectin B1a accounted for 69% of the total residues in muscle and 83% of those in liver and pid=63155; the corresponding values for kidney, fat and milk were 85%, 92% and 77%,respectively.
- The completeness of the total data set provided by the sponsorallowed values for MRLs in cows to be derived statistically.
In recommending MRLs for eprinomectin, the Committee took into account the proportion of the total residues in all tissues over the total withdrawal times reported by the sponsor.
The values for the proportion of the total residues accounted for by the marker residue used to set MRLs for eprinomectin in non-ruminating calves were those established in radiometric studies in cattle. The Committee concluded that the extent of metabolism of eprinomectin in calf tissues would probably be less than or equal to the extent of metabolism of the drug in the same tissues in cattle.
From these MRLs, the theoretical maximum daily intake of eprinomectin residues would be 356 µg.
TRS 888