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Inocuidad y calidad de los alimentos
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Edición en línea: "Residuos en drogas veterinarias"

Ayuda en línea   Terminology

Esta base de datos contiene la información más reciente sobre los niveles máximos de residuos en drogas veterinarias según lo recomendado por JECFA. Todas las monografías publicadas en la FAO sobre Alimentación y Nutrición, Papeles 41, son accesibles en formato electrónico. Estas monografías están sólo disponibles en inglés aunque algunas partes de la base de datos, como la página de preguntas y también una información básica se puede encontrar en árabe, chino, español, francés e inglés.

Medicamento veterinario Deltamethrin
La clase funcional Insecticide
Ultima evaluación 2003
Reunión de JECFA 60
IDA 0-10 µg/kg bw
Estatus de IDA Full
Monografías de residuos  
41-12-deltamethrin.pdf
41-15-deltamethrin.pdf
Definición del residuo Parent drug
Límites máximos para residuos
(LMR) recomendados
CattleFat500 µg/kgF
CattleKidney50 µg/kgF
CattleLiver50 µg/kgF
CattleMilk30 µg/kgF
CattleMuscle30 µg/kgF
ChickenEggs30 µg/kgF
ChickenFat500 µg/kgF
ChickenKidney50 µg/kgF
ChickenLiver50 µg/kgF
ChickenMuscle30 µg/kgF
SalmonMuscle30 µg/kgF
SheepFat500 µg/kgF
SheepKidney50 µg/kgF
SheepLiver50 µg/kgF
SheepMuscle30 µg/kgF
Otras observaciones The Committee took account of the MRLs recommended by the 1990JMPR and recommended the same MRLs for liver, kidney and fat. The Committee noted thatthe concentrations of residues in muscle, milk and eggs are less thantwice the limit of quantification of the analytical methods used andtherefore recommended MRLs based on the sensitivity of the meth-ods.
El resumen de la evaluación In recommending MRLs for deltamethrin, the Committee consideredthe following factors:
- Studies of metabolism were reported only for cattle and chickens.
- Residue-depletion studies with radiolabelled drug and analyticalmethods were available for cattle, chickens and salmon.
- Residue-depletion studies with unlabelled drug were available forcattle, chickens, salmon and sheep.
- The drug is applied topically to the skin.
- The parent drug is absorbed, and its residues are distributed pre-dominantly in body fat and milk fat.
- The parent drug undergoes extensive metabolism in the liver andkidney, with rapid excretion of the metabolic products.
- The parent drug is proposed as the marker residue and is a goodindicator of residues in body fat and milk fat and at the site ofapplication.
- As the concentrations of residues of the marker compound inmuscle, milk and eggs are very low, the limits of quantification ofthe analytical methods used should also be low.
- The limits of quantification of the methods used to determine resi-dues in cattle and chicken tissues are 15µg/kg for muscle, liver,kidney, eggs, milk and milk fat and 45 µg/kg for body fat. The limitsof quantification of the methods used for salmon muscle and skinare 15 and 14µg/kg, respectively.
- The maximum concentration of total residues of [14C]deltamethrinin cattle and poultry was 37µg (<7% of the ADI).
- The concentrations of total residues and residues of the parent drugin salmon muscle and skin were less than twice the limit of quanti-fication at all times. The Committee extended the MRL to allSalmonidae even though the metabolism of deltamethrin in thisfamily was not investigated.
- The residues other than the parent drug may be assumed not tohave the neuronal or toxicological activity of deltamethrin.....
TRS 893