Edition en ligne: "Résidus pour les médicaments vétérinaires"

Aide en ligne Terminology

Cette base de données contient l'information la plus récente sur les niveaux de résidus maximum pour les médicaments vétérinaires recommandés par JECFA. Toute la documentation publiée dans l'étude FAO Alimentation et Nutrition No. 41 est disponible en ligne en format numérique. Cette documentation existe seulement en Anglais, tandis que les pages d'information générale et une partie de la base de données sont traduites en Anglais, Français, Espagnol, Arabe et Chinois.

Médicament vétérinaire

Cyfluthrin

Classe fonctionnelle

Insecticide

Dernière évaluation

1997

Réunion de JECFA

DJA

0-20 µg/kg bw

Statut de la DJA

Full

Monographies des résidus

41-10-cyfluthrin.pdf

Définition du résidu

Parent drug

Limites maximales de résidu
(LMR) recommandés

Cattle	Fat	200 µg/kg	F
Cattle	Kidney	20 µg/kg	F
Cattle	Liver	20 µg/kg	F
Cattle	Milk	40 µg/l	F
Cattle	Muscle	20 µg/kg	F

Autres remarques

Résumé de l'évaluation

The Committee confirmed the AD1 of 0-20µg per kg of body weightpreviously allocated by the 1987 Joint FAO/WHO Meeting on Pesti-cide Residues. This would result in a maximum AD1 of 1200µg for a60-kg person.
In recommending MRLs, the Committee also took into account thefollowing factors:
- Fat was the only suitable target tissue.
- The concentrations of residue in liver and kidney are about one-tenth of those in fat.
- The parent compound was the marker residue and the only residueof concern.
- None of the available residue studies had been conducted exactly atthe upper limit of the recommended dose range (0.5mg per kg ofbody weight) and with repeated dosing at 28-day intervals, theshortest recommended time interval for repetition of treatment.
The available data showed that:
- estimates of the maximum residue concentrations resultingfrom a given single dose could be obtained by linear inter-polation of the data obtained with other similar doses and pid=63155;
- only studies with identical formulations of cyfluthrin could becompared quantitatively and pid=63155;
- the kinetics of repeated treatment could be described bysuperimposing the data obtained from single-dose treatmentswith the same formulation and pid=63155;
- the results obtained after identical treatment could vary greatlyfrom animal to animal.
TRS 879