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Edition en ligne: "Résidus pour les médicaments vétérinaires"

Aide en ligne   Terminology

Cette base de données contient l'information la plus récente sur les niveaux de résidus maximum pour les médicaments vétérinaires recommandés par JECFA. Toute la documentation publiée dans l'étude FAO Alimentation et Nutrition No. 41 est disponible en ligne en format numérique. Cette documentation existe seulement en Anglais, tandis que les pages d'information générale et une partie de la base de données sont traduites en Anglais, Français, Espagnol, Arabe et Chinois.

Médicament vétérinaire Streptomycin
Classe fonctionnelle Antimicrobial agent
Dernière évaluation 2002
Réunion de JECFA 58
DJA 0-50 µg/kg bw
Statut de la DJA Full
Monographies des résidus  
41-7-dihydrostreptomycin_streptomycin.pdf
41-10-dihydrostreptomycin_streptomycin.pdf
41-12-dihydrostreptomycin_streptomycin.pdf
41-14-streptomycins.pdf
Définition du résidu Sum of dihydrostreptomycin and streptomycin
Limites maximales de résidu
(LMR) recommandés
CattleFat600 µg/kgF
CattleKidney1000 µg/kgF
CattleLiver600 µg/kgF
CattleMilk200 µg/kgF
CattleMuscle600 µg/kgF
ChickenFat600 µg/kgF
ChickenKidney1000 µg/kgF
ChickenLiver600 µg/kgF
ChickenMuscle600 µg/kgF
PigFat600 µg/kgF
PigKidney1000 µg/kgF
PigLiver600 µg/kgF
PigMuscle600 µg/kgF
SheepFat600 µg/kgF
SheepKidney1000 µg/kgF
SheepLiver600 µg/kgF
SheepMilk200 µg/kgF
SheepMuscle600 µg/kgF
Autres remarques See dihydrostreptomycin/streptomycin
Résumé de l'évaluation At its present meeting, the Committee considered that the sponsors had provided satisfactory answers to all of its requests made at the forty-third meeting. It therefore decided to delete the temporary status of the MRLs, except that for milk. The MRLs for muscle, liver and fat were raised to 600 µg/kg, to take into account the twofold higher LOQ of the bioassay method compared with the HPLC method. The recommended MRL for kidney was 1000 µg/kg in cattle, pigs, sheep and chickens. The MRLs were expressed as the sum of the concentrations of dihydrostreptomycin and streptomycin.
From the above MRL values, the theoretical maximum daily intake of dihydrostreptomycin and streptomycin residues is 620 µg (equivalent to 21% of the maximum ADI), based on a daily food intake of 300 g of muscle, 100 g of liver, 50g each of liver and fat, and 1.5 kg of milk. If milk is excluded, the theoretical maximum daily intake is 320 µg or 11% of the ADI.
TRS 893.
The submitted HPLC method with fluorescence detection met the performance criteria for the analysis of dihydrostreptomycin and streptomycin in cow's and sheep's milk and was judged to be acceptable for routine monitoring of milk samples.
Although the study of residue depletion in sheep's milk had not been requested by the Committee, it provided the data needed to recommend an MRL for the combined residues of dihydrostreptomycin and streptomycin in sheep's milk. Therefore, the Committee recommended that the temporary designation for cow's milk of 200 µg/kg, measured as the combined residuesof dihydrostreptomycin and streptomycin, be removed and that theMRL of 200 µg/kg be extended to sheeps milk for the combined residues'of dihydrostreptomycin and streptomycin.
TRS 911