Edition en ligne: "Résidus pour les médicaments vétérinaires"

Aide en ligne Terminology

Cette base de données contient l'information la plus récente sur les niveaux de résidus maximum pour les médicaments vétérinaires recommandés par JECFA. Toute la documentation publiée dans l'étude FAO Alimentation et Nutrition No. 41 est disponible en ligne en format numérique. Cette documentation existe seulement en Anglais, tandis que les pages d'information générale et une partie de la base de données sont traduites en Anglais, Français, Espagnol, Arabe et Chinois.

Médicament vétérinaire

Sulfadimidine

Classe fonctionnelle

Antimicrobial agent

Dernière évaluation

1994

Réunion de JECFA

DJA

0-50 µg/kg bw

Statut de la DJA

Full

Monographies des résidus

41-2-general_consideration_for_sulfamidine_and_sulfathiazole.pdf

41-2-sulfadimidine.pdf

Définition du résidu

Parent drug

Limites maximales de résidu
(LMR) recommandés

Cattle	Fat	100 µg/kg	F
Cattle	Kidney	100 µg/kg	F
Cattle	Liver	100 µg/kg	F
Cattle	Milk	25 µg/kg	F
Cattle	Muscle	100 µg/kg	F
Pig	Fat	100 µg/kg	F
Pig	Kidney	100 µg/kg	F
Pig	Liver	100 µg/kg	F
Pig	Muscle	100 µg/kg	F
Poultry	Fat	100 µg/kg	F
Poultry	Kidney	100 µg/kg	F
Poultry	Liver	100 µg/kg	F
Poultry	Muscle	100 µg/kg	F
Sheep	Fat	100 µg/kg	F
Sheep	Kidney	100 µg/kg	F
Sheep	Liver	100 µg/kg	F
Sheep	Muscle	100 µg/kg	F

Autres remarques

Résumé de l'évaluation

The Committee recognized that information on hypersensitivity reactions resulting from the ingestion of tissues containing sulfonamides would be extremely difficult, if not impossible, to obtain. In line with the previous evaluation, the Committee therefore recommended that the MRLs should be set as low as practicable possible in naccordance with Good Practice in the Use of Veterinary Drugs. In doing so, the Committee recognized that these concentrations would then be below the levels considered significant from the point of view of microbiological concern. On this basis, the Committee concluded that the MRLs for sulfadimidine should remain as recommended at its thirty-fourth meeting since methods are routinely available for national residue monitoring. The values recommended for cattle, sheep, pigs and poultry are 100 µg/kg as sulfadimidine in muscle, liver, kidney and fat. The recommended MRL for milk as sulfadimidine is 25 µg/l. With these MRLs, the theoretical maximum daily intake of sulfadimidine residues is 87.5 µg/day, which is considerably less than the maximum ADI of 3 mg for a 60 kg person. The residue data available for eggs indicate that compliance with current practices in egg production would result in very high concentrations of sulfadimidine in eggs. For this reason, the Committee considered that sulfadimidine should not be used in laying hens, and did not recommend an MRL for eggs.
TRS 851