Edition en ligne: "Résidus pour les médicaments vétérinaires"

Aide en ligne Terminology

Cette base de données contient l'information la plus récente sur les niveaux de résidus maximum pour les médicaments vétérinaires recommandés par JECFA. Toute la documentation publiée dans l'étude FAO Alimentation et Nutrition No. 41 est disponible en ligne en format numérique. Cette documentation existe seulement en Anglais, tandis que les pages d'information générale et une partie de la base de données sont traduites en Anglais, Français, Espagnol, Arabe et Chinois.

Médicament vétérinaire

Eprinomectin

Classe fonctionnelle

Antiparasitic

Dernière évaluation

1998

Réunion de JECFA

DJA

0-10 µg/kg bw

Statut de la DJA

Full

Monographies des résidus

41-12-estradiol_17-beta_progesterone_testosterone.pdf

41-1-progesterone.pdf

Définition du résidu

Eprinomectin B1a

Limites maximales de résidu
(LMR) recommandés

Cattle	Fat	250 µg/kg	F
Cattle	Kidney	300 µg/kg	F
Cattle	Liver	2000 µg/kg	F
Cattle	Milk	20 µg/l	F
Cattle	Muscle	100 µg/kg	F

Autres remarques

Résumé de l'évaluation

In recommending MRLs for various tissue matrices, the Committee took the following factors into consideration:
- The drug is for use in dairy and beef cattle.
- The limits of quantification of the analytical methods are 1.0 µg/l and 2.0 µg/kg for milk and tissues, respectively.
- The marker residue is eprinomectin B1a.
- The marker residue is always the predominant residue in both tissues and milk. Eprinomectin B1a accounted for 69% of the total residues in muscle and 83% of those in liver and pid=63155; the corresponding values for kidney, fat and milk were 85%, 92% and 77%,respectively.
- The completeness of the total data set provided by the sponsorallowed values for MRLs in cows to be derived statistically.
In recommending MRLs for eprinomectin, the Committee took into account the proportion of the total residues in all tissues over the total withdrawal times reported by the sponsor.
The values for the proportion of the total residues accounted for by the marker residue used to set MRLs for eprinomectin in non-ruminating calves were those established in radiometric studies in cattle. The Committee concluded that the extent of metabolism of eprinomectin in calf tissues would probably be less than or equal to the extent of metabolism of the drug in the same tissues in cattle.
From these MRLs, the theoretical maximum daily intake of eprinomectin residues would be 356 µg.
TRS 888