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Безопасность и качество пищевых продуктов
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Online help Terminology
This database contains the most recent information on maximum residue levels for veterinary drugs as recommended by JECFA. All monographs published in the FAO Food and Nutrition Papers 41 can be accessed in an electronic format. These monographs are available only in English although some parts of the database, the query page as well as the background information are provided in English, French, Spanish, Arabic and Chinese.
| Veterinary Drug |
Apramycin |
| Functional class |
Antibacterial agent |
| Latest evaluation |
2011 |
| JECFA meeting |
75 |
| ADI |
0-30 µg/kg bw |
| ADI status |
Full |
| Residue monographs |
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| Marker residue |
Apramycin |
Maximum residue limits (MRL) recommended |
| Cattle | Kidney | 5000 µg/kg | T | | Chicken | Kidney | 5000 µg/kg | T |
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| Other remarks |
Because of data limitations, the Committee was unable to recommend MRLs in tissues and species other than cattle kidney and chicken kidney. Data is requested to provide improved analytical methods with better performance and lower LOQs and residue depletion studies with appropriate sampling points close to the zero withdrwal periods for all tissue and species. The validated analytical methods and residue depletion studies are requested by the end of 2014. |
| Summary of the evaluation |
The Committee established an ADI on the basis of microbiological effects. Using the limits of quantification (LOQs) of the analytical methods as calculated by the Committee as the residue levels for muscle, fat and liver, together with the proposed MRL for kidney, the theoretical intake in the worst-ase scenariiio would be around 1400 µg/day and would not exceed the upper bound of the ADI. |
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