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Безопасность и качество пищевых продуктов
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Online help Terminology
This database contains the most recent information on maximum residue levels for veterinary drugs as recommended by JECFA. All monographs published in the FAO Food and Nutrition Papers 41 can be accessed in an electronic format. These monographs are available only in English although some parts of the database, the query page as well as the background information are provided in English, French, Spanish, Arabic and Chinese.
| Veterinary Drug |
Chlortetracycline |
| Functional class |
Antimicrobial agent |
| Latest evaluation |
1998 |
| JECFA meeting |
50 |
| ADI |
0-30 µg/kg bw |
| ADI status |
Full |
| Residue monographs |
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| Marker residue |
Parent drug, singly or in combination with TC, OTC |
Maximum residue limits (MRL) recommended |
| Cattle | Kidney | 1200 µg/kg | F | | Cattle | Liver | 600 µg/kg | F | | Cattle | Milk | 100 µg/l | F | | Cattle | Muscle | 200 µg/kg | F | | Pig | Kidney | 1200 µg/kg | F | | Pig | Liver | 600 µg/kg | F | | Pig | Muscle | 200 µg/kg | F | | Poultry | Eggs | 400 µg/kg | F | | Poultry | Kidney | 1200 µg/kg | F | | Poultry | Liver | 600 µg/kg | F | | Poultry | Muscle | 200 µg/kg | F | | Sheep | Kidney | 1200 µg/kg | F | | Sheep | Liver | 600 µg/kg | F | | Sheep | Milk | 100 µg/l | F | | Sheep | Muscle | 200 µg/kg | F |
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| Other remarks |
Group ADI for tetracycline, oxytetracycline and chlortetracycline, established at the fiftieth meeting (1998) |
| Summary of the evaluation |
With the establishment of an AD1 of 0-30 µg/kg of body weight, the Committee recognized that the constraints placed on the recommended MRLs no longer exist. In particular, the limits of quantification of the currently available methods for determination of residues in tissues that have been performance tested would permit the satisfactory control of residues at twice the value of the previously established MRLs. The analytical methods for monitoring tetracyclines in milk have a limit of quantification of 15 µg/l, considerably lower than the present MRL for milk. Accordingly, the Committee decided to double the recommended MRL values for edible tissues. The resulting MRLs are consistent with the available analytical methods and with good practice in the use of veterinary drugs. The Committee did not have information on the concentration of tetracyclines in milk that would interfere with the production of milk products such as yogurt and therefore made no change to the recommended MRL for milk. TRS 888 |
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