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Безопасность и качество пищевых продуктов
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Online help Terminology
This database contains the most recent information on maximum residue levels for veterinary drugs as recommended by JECFA. All monographs published in the FAO Food and Nutrition Papers 41 can be accessed in an electronic format. These monographs are available only in English although some parts of the database, the query page as well as the background information are provided in English, French, Spanish, Arabic and Chinese.
| Veterinary Drug |
Benzylpenicillin |
| Functional class |
Antimicrobial agent |
| Latest evaluation |
1990 |
| JECFA meeting |
36 |
| ADI |
<30 µg/person/d |
| ADI status |
Full |
| Residue monographs |
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| Marker residue |
Parent drug |
Maximum residue limits (MRL) recommended |
| All species | Kidney | 50 µg/kg | F | | All species | Liver | 50 µg/kg | F | | All species | Milk | 4 µg/kg | F | | All species | Muscle | 50 µg/kg | F |
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| Other remarks |
ADI expressed as the penicillin moiety |
| Summary of the evaluation |
In reaching a decision on a recommended MRL, the Committee considered the following points: (a) The drug is used in both meat- and milk-producing animals. (b) The maximum permitted daily intake of benzylpenicillin is 30 µg .(c) Bioassay methods for screening benzylpenicillin are widely used and are likely to be the methods of choice for most Member States in the foreseeable future. ( d ) The analytical methods that are available for measuring residues in milk are much more sensitive than those for meat. (e) Chemical assay methods for confirming bioassay results are becoming increasingly available, but at present they are less sensitive than bioassay methods. An MRL for total residues of benzylpenicillin of 50 µg/kg forliver, kidney, and muscle (all species) and an MRL of 4 µg/kg for milk are recommended. Thus, the estimated maximum daily intake of benzylpenicillin residues is 15 µg for muscle, 5 µg for liver, 3 µg for kidney, and 6 µg for milk, yielding a total maximum daily intake of 29 µg. The concentration of residues in fat is non-detectable. TRS 799 |
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