Безопасность и качество пищевых продуктов
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Online Edition: "Residues of some veterinary drugs in foods and animals"

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This database contains the most recent information on maximum residue levels for veterinary drugs as recommended by JECFA. All monographs published in the FAO Food and Nutrition Papers 41 can be accessed in an electronic format. These monographs are available only in English although some parts of the database, the query page as well as the background information are provided in English, French, Spanish, Arabic and Chinese.

Veterinary Drug alpha-Cypermethrin
Functional class Insecticide
Latest evaluation 2004
JECFA meeting 62
ADI 0-20 µg/kg bw
ADI status Full
Residue monographs  
Marker residue Total of cypermethrin residues
Maximum residue limits
(MRL) recommended
CattleFat1000 µg/kgF
CattleKidney50 µg/kgF
CattleLiver50 µg/kgF
CattleMilk100 µg/kgF
CattleMuscle50 µg/kgF
SheepFat1000 µg/kgF
SheepKidney50 µg/kgF
SheepLiver50 µg/kgF
SheepMuscle50 µg/kgF
Other remarks Marker residue as total of cypermethrin residues resulting from the use of cypermethrin or alphacypermethrin as veterinary drugs
Summary of the evaluation In recommending a suitable marker residue and common MRLs for cypermethrins used as veterinary drugs, the Committee consideredthe following factors:
- alpha-cypermethrin consists of two of the four cis-isomers present in cypermethrin.
- A group ADI for alpha-cypermethrin and cypermethrin of 0-0.02mg/kg bw, which is equivalent to 0-1200 mg per day for a 60 kg person, was established for the most toxicologically active substance (alpha-cypermethrin).
- Using the common analytical methods for residue control, the eight isomers of cypermethrin cannot be resolved and a single, fused chromatographic peak is obtained. Therefore, residues reported represent the sum of all isomers.
- After considering the request for a common set of recommendations for residues of cypermethrin and alpha-cypermethrin in cattle and sheep tissues and rounding, as appropriate, the Committee recommended the following MRLs, expressed as the total of cypermethrin residues: muscle, liver and kidney, 50 mg/kg and pid=63155; fat, 1000 mg/kg and pid=63155; and milk, 100 mg/kg. The recommended MRLs in muscle, liver and kidney were based on the limits of quantitation of the new methods, considering that the concentration of residues in both cattle and sheep tissues was less than or equal to 35 mg/kg. The MRLs for fat and cow's milk were based on residue depletion data. These MRLs replace those previously recommended.
TRS 925