网络版“:食品和家畜中的一部分兽药残留”

在线帮助词汇

本数据库保存了关于JECFA推荐的兽药最高残留量的最近信息。粮农组织第41号食品和营养文件公布的所有专题文章电子版均可提供。这些专题文章仅有英文，虽然数据库某些部分、询问页和背景资料有英文、法文、西班牙文、阿拉伯文和中文。

兽药

Gentamicin

功能分类

Antimicrobial agent

最新评价

1998

食品添加剂和污染物联合专家委员会

每日允许摄入量

0-20 µg/kg bw

每日允许摄入量状况

Full

残留量专题文集

41-11-gentamicin.pdf

41-7-gentamicin.pdf

残留标示物

Parent drug

建议的最高残留限量

Cattle	Fat	100 µg/kg	F
Cattle	Kidney	5000 µg/kg	F
Cattle	Liver	2000 µg/kg	F
Cattle	Milk	200 µg/l	F
Cattle	Muscle	100 µg/kg	F
Pig	Fat	100 µg/kg	F
Pig	Kidney	5000 µg/kg	F
Pig	Liver	2000 µg/kg	F
Pig	Muscle	100 µg/kg	F

其他说明

评价概要

In recommending MRLs for gentamicin, the Committee took into account the following factors:
- An ADI of 0-20 µg/kg of body weight, based on a microbiological end-point, was established. This corresponds to a maximum AD1 of 1200 µg for a 60 kg person.
- Gentamicin residues persist in kidney and liver, but deplete rapidly in muscle, fat and milk. Kidney and liver are therefore considered to be the appropriate target tissues.
- A suitable analytical method is available for measurement of gentamicin residues in edible tissues and milk. The limits of quantification were 100 µg/kg for muscle and fat, 200 µg/kg for liver, 1000 µg/kg for kidney and 100µg/l for milk.
- The parent drug is the marker residue.
The MRLs recommended would result in a theoretical maximum daily intake of 785 µg, based on a daily food intake of 300 g of muscle, 100 g of liver, 50 g each of kidney and fat, and 1.5 l of milk.
TRS 888