Food safety and quality: details

兽药

Sulfadimidine

功能分类

Antimicrobial agent

最新评价

1994

食品添加剂和污染物联合专家委员会

每日允许摄入量

0-50 µg/kg bw

每日允许摄入量状况

Full

残留量专题文集

41-2-general_consideration_for_sulfamidine_and_sulfathiazole.pdf

41-2-sulfadimidine.pdf

残留标示物

Parent drug

建议的最高残留限量

Cattle	Fat	100 µg/kg	F
Cattle	Kidney	100 µg/kg	F
Cattle	Liver	100 µg/kg	F
Cattle	Milk	25 µg/kg	F
Cattle	Muscle	100 µg/kg	F
Pig	Fat	100 µg/kg	F
Pig	Kidney	100 µg/kg	F
Pig	Liver	100 µg/kg	F
Pig	Muscle	100 µg/kg	F
Poultry	Fat	100 µg/kg	F
Poultry	Kidney	100 µg/kg	F
Poultry	Liver	100 µg/kg	F
Poultry	Muscle	100 µg/kg	F
Sheep	Fat	100 µg/kg	F
Sheep	Kidney	100 µg/kg	F
Sheep	Liver	100 µg/kg	F
Sheep	Muscle	100 µg/kg	F

其他说明

评价概要

The Committee recognized that information on hypersensitivity reactions resulting from the ingestion of tissues containing sulfonamides would be extremely difficult, if not impossible, to obtain. In line with the previous evaluation, the Committee therefore recommended that the MRLs should be set as low as practicable possible in naccordance with Good Practice in the Use of Veterinary Drugs. In doing so, the Committee recognized that these concentrations would then be below the levels considered significant from the point of view of microbiological concern. On this basis, the Committee concluded that the MRLs for sulfadimidine should remain as recommended at its thirty-fourth meeting since methods are routinely available for national residue monitoring. The values recommended for cattle, sheep, pigs and poultry are 100 µg/kg as sulfadimidine in muscle, liver, kidney and fat. The recommended MRL for milk as sulfadimidine is 25 µg/l. With these MRLs, the theoretical maximum daily intake of sulfadimidine residues is 87.5 µg/day, which is considerably less than the maximum ADI of 3 mg for a 60 kg person. The residue data available for eggs indicate that compliance with current practices in egg production would result in very high concentrations of sulfadimidine in eggs. For this reason, the Committee considered that sulfadimidine should not be used in laying hens, and did not recommend an MRL for eggs.
TRS 851

网络版“:食品和家畜中的一部分兽药残留”