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Food safety and quality
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在线帮助 词汇
本数据库保存了关于JECFA推荐的兽药最高残留量的最近信息。粮农组织第41号食品和营养文件公布的所有专题文章电子版均可提供。这些专题文章仅有英文, 虽然数据库某些部分、询问页和背景资料有英文、法文、西班牙文、阿拉伯文和中文。
| 兽药 |
Nicarbazin |
| 功能分类 |
Antiprotozoal agent |
| 最新评价 |
1998 |
| 食品添加剂和污染物联合专家委员会 |
50 |
| 每日允许摄入量 |
0-400 µg/kg bw |
| 每日允许摄入量状况 |
Full |
| 残留量专题文集 |
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| 残留标示物 |
N,N-bis(4-nitrophenylurea) |
| 建议的最高残留限量 |
| Chicken (broilers) | Fat/Skin | 200 µg/kg | F | | Chicken (broilers) | Kidney | 200 µg/kg | F | | Chicken (broilers) | Liver | 200 µg/kg | F | | Chicken (broilers) | Muscle | 200 µg/kg | F |
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| 其他说明 |
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| 评价概要 |
In reaching its decision on MRLs for nicarbazin in broiler chickens, the Committee took the following factors into consideration: - An ADI of 0-400 µg/kg of body weight was established. This would result in a maximum ADI of the parent drug and/or its equivalentsof 24000 µg for a 60 kg person. - The limit of quantification of the analytical method is 0.1 mg/kg for all tissues. - The parent drug is for use in broiler chickens only during the first 28 days after hatching. - The marker residue is N,N'-bis-(4-nitrophenyl)urea. - The marker residue accounts for 65% of the total residues inmuscle and 45%, 15% and 90% of the total residues in liver, kidney and skin with adhering fat, respectively. - The recommended MRLs are consistent with Good Practice in the Use of Veterinary Drugs. The Committee recommended MRLs of 200 µg/kg for muscle, liver, kidney and skin with adhering fat in broiler chickens. From these MRLs, the theoretical maximum daily intake of residues as nicarbazin equivalents is 214 µg, based on a daily food intake of 300 g of muscle, 100 g of liver, and 50 g each of kidney and fat. TRS 888 |
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