Food safety and quality: details

兽药

Deltamethrin

功能分类

Insecticide

最新评价

2003

食品添加剂和污染物联合专家委员会

每日允许摄入量

0-10 µg/kg bw

每日允许摄入量状况

Full

残留量专题文集

41-12-deltamethrin.pdf

41-15-deltamethrin.pdf

残留标示物

Parent drug

建议的最高残留限量

Cattle	Fat	500 µg/kg	F
Cattle	Kidney	50 µg/kg	F
Cattle	Liver	50 µg/kg	F
Cattle	Milk	30 µg/kg	F
Cattle	Muscle	30 µg/kg	F
Chicken	Eggs	30 µg/kg	F
Chicken	Fat	500 µg/kg	F
Chicken	Kidney	50 µg/kg	F
Chicken	Liver	50 µg/kg	F
Chicken	Muscle	30 µg/kg	F
Salmon	Muscle	30 µg/kg	F
Sheep	Fat	500 µg/kg	F
Sheep	Kidney	50 µg/kg	F
Sheep	Liver	50 µg/kg	F
Sheep	Muscle	30 µg/kg	F

其他说明

The Committee took account of the MRLs recommended by the 1990JMPR and recommended the same MRLs for liver, kidney and fat. The Committee noted thatthe concentrations of residues in muscle, milk and eggs are less thantwice the limit of quantification of the analytical methods used andtherefore recommended MRLs based on the sensitivity of the meth-ods.

评价概要

In recommending MRLs for deltamethrin, the Committee consideredthe following factors:
- Studies of metabolism were reported only for cattle and chickens.
- Residue-depletion studies with radiolabelled drug and analyticalmethods were available for cattle, chickens and salmon.
- Residue-depletion studies with unlabelled drug were available forcattle, chickens, salmon and sheep.
- The drug is applied topically to the skin.
- The parent drug is absorbed, and its residues are distributed pre-dominantly in body fat and milk fat.
- The parent drug undergoes extensive metabolism in the liver andkidney, with rapid excretion of the metabolic products.
- The parent drug is proposed as the marker residue and is a goodindicator of residues in body fat and milk fat and at the site ofapplication.
- As the concentrations of residues of the marker compound inmuscle, milk and eggs are very low, the limits of quantification ofthe analytical methods used should also be low.
- The limits of quantification of the methods used to determine resi-dues in cattle and chicken tissues are 15µg/kg for muscle, liver,kidney, eggs, milk and milk fat and 45 µg/kg for body fat. The limitsof quantification of the methods used for salmon muscle and skinare 15 and 14µg/kg, respectively.
- The maximum concentration of total residues of [14C]deltamethrinin cattle and poultry was 37µg (<7% of the ADI).
- The concentrations of total residues and residues of the parent drugin salmon muscle and skin were less than twice the limit of quanti-fication at all times. The Committee extended the MRL to allSalmonidae even though the metabolism of deltamethrin in thisfamily was not investigated.
- The residues other than the parent drug may be assumed not tohave the neuronal or toxicological activity of deltamethrin.....
TRS 893

网络版“:食品和家畜中的一部分兽药残留”