COMBAT ('Controlling and progressively Minimizing the Burden of Animal Trypanosomosis') is a four-year project funded by the European Commission (EC) in the framework of the Horizon 2020 research and innovation programme (www.combat-project.eu). The project is coordinated by the French Agricultural Research Centre for International Development (CIRAD), it involves 21 participating institutions...

African animal trypanosomosis (AAT) is a major constraint on livestock health in sub-Saharan Africa. With no vaccine, trypanocidal drugs are the mainstay of control. Recently there have been step change advances towards more effective AAT control, through research on treatment failure, drug resistance and quality of trypanocidal drugs, and development...

Human African trypanosomiasis (HAT), also known as sleeping sickness, is a vector-borne disease transmitted by tsetse flies. The gambiense form of HAT (gHAT) is found in western and central Africa, and it is mainly anthroponotic (i.e. transmitted from human to human via the tsetse vector); the rhodesiense form is found...

Great efforts have been made over several decades to control African trypanosomosis and its vectors. However, whilst over the past twenty years great advances have been made towards the elimination of sleeping sickness, progress in the control of animal trypanosomosis (AT) has been much more limited. To help face these...