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Book (stand-alone)Evaluation of certain veterinary drug residues in food: ninety-fourth report of the Joint FAO/WHO Expert Committee on Food Additives
WHO Technical Report Series, no. 1041
2022Also available in:
No results found.This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in food. The first part of the report considers general principles regarding the evaluation of residues of veterinary drugs within the terms of reference of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). It covers topics such as the parallel review process; estimation of dietary exposure to veterinary drug residues; a risk-based decision tree approach for safety evaluation; assessment of the potential effects of residues on the human intestinal microbiome. Summaries follow the Committee’s evaluations of toxicological and residue data on a variety of veterinary drugs: two antiparasitic agents (imidacloprid, ivermectin) and one coccidiostat (nicarbazin). Additionally, further evaluation of the parasiticide selamectin is included as part of a pilot in support of the proposed parallel review process. Annexed to the report is a summary of the Committee’s recommendations on these drugs, including acceptable daily intakes and proposed maximum residue limits. -
Book (stand-alone)Toxicological evaluation of certain veterinary drug residues in food: prepared by the ninety-fourth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA) 2023
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No results found.This volume contains monographs prepared at the ninety-fourth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), which met in a virtual format, from 16 to 27 May 2022. The toxicological monographs in this volume summarize data on the veterinary drug residues that were evaluated toxicologically by the Committee: imidacloprid and nicarbazin. Annexed to the report is a summary of the Committee’s recommendations on these and other drugs (ivermectin and selamectin) discussed at the ninety-fourth meeting, including acceptable daily intakes (ADIs), acute reference doses (ARfDs) and proposed maximum residue limits (MRLs). This volume and others in the WHO Food Additives Series contain information that is useful to those who produce and use food additives and veterinary drugs, and those involved with controlling contaminants in food, government and food regulatory officers, industrial testing laboratories, toxicological laboratories and universities. -
Book (stand-alone)Residue Evaluation of Certain Veterinary Drugs. Joint FAO/WHO Expert Committee on Food Additives (JECFA). 75th Meeting. FAO JECFA Monographs 12 2012
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No results found.The monographs in this volume of the FAO JECFA Monographs on the residues of, statements on, or other parameters of the veterinary drugs on the agenda were prepared by the invited experts for the Seventy-fifth Meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), held in Rome, Italy, 7–17-November 2011. This was the nineteenth meeting of JECFA convened specifically to consider residues of veterinary drugs in food-producing animal species. The Committee had evaluated residues o f veterinary drugs at its 12th, 26th, 27th, 32nd, 34th, 36th, 38th, 40th,42nd, 43rd, 45th, 47th, 48th, 50th, 52nd, 54th, 58th, 60th, 62nd, 66th and 70th meetings (JECFA, various dates 1969–2010). The tasks for the Committee were to further elaborate principles for evaluating the safety of residues of veterinary drugs in food and for establishing acceptable daily intakes (ADIs) and recommend maximum residue limits (MRLs) for substances on the agenda when they are administered to food-producing an imals in accordance with good veterinary practice in the use of veterinary drugs. The enclosed monographs provided the scientific basis for the recommendations of MRLs. There is an important feature to bring to the attention of readers. This volume of the FAO JECFA Monographs is the third in a new format for the presentation of monographs from meetings of the Committee specifically devoted to residues of specific veterinary drugs in food. It was also the seventh meeting of JECFA subsequent to th e completion of the workshop to update the principles and methods of risk assessment for MRLs for pesticides and veterinary drugs, held jointly by FAO/RIVM/WHO, in Bilthoven, The Netherlands, 7– 11 November 2005. The outcomes of this workshop are incorporated in the Environmental Health Criteria, No. 240, publication Principles and methods for the risk assessment of chemicals in food, WHO, 2009. Specifically, the Committee continued to implement some of the more significant recommendations in th e workshop report, including the concept of using median residue values to estimate daily intakes of residues of veterinary drugs in food for chronic exposure intake estimates.
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