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Cell-based food: its safety and its future role

Stakeholder roundtable meeting report, Tel Aviv, Israel, 7 September 2022








FAO. 2023. Cell-based food: its safety and its future role  Stakeholder roundtable meeting report, Tel Aviv, Israel, 7 September 2022. Rome.



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    Book (stand-alone)
    Food safety aspects of cell-based food 2023
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    Cell-based food production, which is the field of growing animal agricultural products directly from cell cultures, has been explored as an alleged sustainable alternative to the conventional livestock agricultural system. As commercial cell-based food production continues to expand, the urgency increases to address one of the most important questions of consumers, the question of food safety. Thus, the Food and Agriculture Organization of the United Nations (FAO), in collaboration with the World Health Organization (WHO), has developed the present document to engage with respective Members and relevant stakeholders by proactively sharing the current knowledge to identify concrete ways to inform consumers and all other stakeholders about the food safety considerations for cell-based food products. This document includes a literature synthesis of relevant terminology issues, principles of cell-based food production processes and the global landscape of regulatory frameworks for cell-based food production. Case studies from Israel, Qatar and Singapore have been included to highlight different scopes, structures and contexts surrounding their regulatory frameworks for cell-based food. The results of the FAO-led Expert Consultation, where comprehensive food safety hazard identification was conducted, form the core of the document and the identified hazards are summarized with causal-chain examples. The way forward will consist of continuing to invest in research and development in order to understand whether the alleged benefits in increased sustainability can be realized. In this regard, it will be important to closely observe as to what extent, if any, cell-based foods result in differences from conventionally produced foods.
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    Booklet
    Food safety aspects of cell-based food
    Background document two - Generic production process
    2022
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    Cell-based food production encompasses a variety of techniques and technologies that enable the production of animal proteins from in vitro grown animal or microbial cells. Most of them are currently under development and some are ready to be scaled up for commercialization. Cell-based food production can aim at producing a wide variety of products with different animal proteins from beef, pork, poultry, fish, shellfish and many others, including dairy and egg products. Therefore, it is not optimal to develop a detailed overview of the production process of cell-based food as a whole, but a generic understanding of a high-level process for cell-based food production can be illustrated. By having such a basic understanding, potential hazard identification, the first step in food safety assessment, can be initiated. To ensure the food safety of cell-based food products, it is important for the food safety competent authorities to identify specific potential hazards for effective national food control systems. The scientific literature review was conducted to provide an overview of the cell-based food production processes currently being practised. The document also illustrates a limited number of the key potential hazards that have been identified through the review of the available literature, although further work is necessary to provide a comprehensive list of food safety hazards. The document serves as a basis to initiate the first step of the appropriate food safety assessment, which will eventually support both cell-based food developers and regulators worldwide in making informed decisions on setting up food safety assurance systems.
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    Booklet
    Cell-based food and precision fermentation – Products, safety and the future role
    Stakeholder roundtable meeting report, Shanghai, China, 6 November 2023
    2024
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    As the global demand for proteins and specific nutrients grows, many people are looking into opportunities to expand the scope of diverse and sustainable sources of such nutrients. Food safety is one of the prominent key issues to ascertain before such products go into the market, and various competent authorities are working to identify and address potential food safety issues and their implications. After the first stakeholder meeting on cell-based food organized by the Food and Agriculture Organization of the United Nations (FAO) in collaboration with the Government of Israel, many experts suggested that FAO maintain such dialogues to regularly update the knowledge of this fast-improving technology. This led to the stakeholder meeting organized by FAO jointly with the Government of China in November 2023, which considered precision fermentation besides cell-based food. The present report summarized the results of the meeting attended by a total of 55 participants in Shanghai, China on 6 November 2023. The meeting provided a snapshot of the state of development of these particular technologies and the industry in 2023. As an increasing number of countries are reviewing the regulatory applications, valid examples of how to assess product safety have become available. All participants recognized that open discussions between stakeholders and regulators are key when it comes to clarifying important aspects of food safety, and that supporting the relevant scientific innovations is vital for achieving the overall food security goals and sustainable food production for the future.

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