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Surveillance data of the Indian Network for Fishery and Animal Antimicrobial Resistance (INFAAR)

An analytical report 2019–2022








FAO. 2024. Surveillance data of the Indian Network for Fishery and Animal Antimicrobial Resistance (INFAAR) – An analytical report 2019–2022. New Delhi.




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    The phenomenon in which bacteria do not respond to antibiotics, when given in accordance with standard treatment guidelines, is called antimicrobial resistance (AMR). It leads to prolonged treatment, longer infectivity of the patient, use of additional and expensive investigations and potentially toxic drugs, and huge economic cost to the patient, society, and the country. AMR has been developing rapidly against even newly discovered antibiotics. The bacteria are versatile and ingenious in developing a plethora of defence mechanisms against antibiotics. Many bacterial species have accumulated resistance to multiple drugs. These are known as multidrug-resistant (MDR) organisms and in layman language as “superbugs”. The spectrum and reach of MDR pathogens have been rapidly increasing. AMR in animal pathogens makes disease treatments ineffective, increases the severity of the disease, reduces productivity and leads to economic losses. In addition, more than half the quantity of antimicrobials used in animals/fish is excreted as waste contaminating soil, water and the environment. This also contributes to the emergence and spread of AMR through selection pressure on microorganisms in the environment. Besides, antimicrobial usage can lead to antimicrobials residues in the edible animal/fish products which are a public health risk.
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    The guidelines provide a regional overview of antimicrobial resistance (AMR) surveillance in aquaculture, including the importance of harmonizing methodologies across the region (Chapter 1). The guidelines also cover approaches to the design of AMR surveillance in aquaculture, from identifying the target population to sampling considerations (Chapter 2). Sample consideration and transport are described in detail, following standing methodologies for disease surveillance in aquaculture (Chapter 3). The laboratory methods are described, from general principles to specific methodologies (Chapter 4). Finally, the guidelines also describe AMR data management including collection, storage, analysis, and presentation (Chapter 5). While Volume 3 provides guidance for carrying out AMR monitoring and surveillance in aquaculture, the other areas in the AMR surveillance framework are covered in the respective volumes of this regional guideline series: Volume 1 (Monitoring and surveillance of antimicrobial resistance in bacteria from healthy food animals intended for consumption), Volume 2 (Monitoring and surveillance in animal pathogens recovered from diseased livestock); Volume 4 (Monitoring bacterial resistance in the animal environment) that will focus on monitoring AMR in bacteria from agriculture settings (such as manure and slurry in livestock farms and aquatic environments), Volume 5 (Monitoring antimicrobial usage in animals at the farm level) and Volume 6 (Monitoring antimicrobial residues in food). Experts from FAO, the Singapore Food Agency and the Singapore National Parks Board led the writing of this volume.
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    Antimicrobial resistance (AMR; also used for “antimicrobial resistant” in this document) is a major global public health concern and a food safety issue. When pathogens become resistant to antimicrobial agents they can pose a greater human health risk as a result of potential treatment failure, loss of treatment options and increased likelihood and severity of disease. Problems related to AMR are inherently related to antimicrobial use in any environment, including human and non-human uses. The use of antimicrobial agents in food producing animals/crops provides a potentially important risk factor for selection and dissemination of AMR microorganisms and determinants from animals/food crops to humans via the consumption of food.

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