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codexalimentarius > Themes > Antimicrobial Resistance

Antimicrobial Resistance

Antimicrobial resistance (AMR) is a major global threat of increasing concern to human and animal health. It also has implications for both food safety and food security and the economic well being of millions of farming households.

Food plays an important role in the development and spread of AMR. The presence of AMR microorganisms in agricultural production systems and food chains is a potential route of exposure for everyone. Good hygiene practices in agriculture, fundamental in achieving food safety, are also key to addressing antimicrobial resistance.

The role of Codex in AMR

Microorganisms (bacteria, parasites, viruses and fungi) in food are potential food safety hazards. The relationship of the use of antimicrobials (agents that can kill microorganisms or stop them from growing) in food-producing animals and the emergence of resistant microorganisms in the food chain is a concern and has been the subject of numerous national and international consultations.

The extent to which the use of antimicrobial agents in food animals (including aquaculture), horticulture or humans contributes to antimicrobial-resistant microorganisms in humans varies between the different microorganisms and different regions.

When humans ingest antimicrobial-resistant microorganisms in food, some species of microorganisms may cause illness. These and other species may also serve as a source of transferable resistance determinants for other microorganisms, including human pathogens.

In recognising the need for a more general and multidisciplinary response to deal with AMR, in 2006 Codex established a first Task Force on Antimicrobial Resistance to develop science-based guidance on how to assess and manage the risks to human health associated with the presence in food and feed (including aquaculture) and the transmission through food and feed of antimicrobial resistant microorganisms. A second Task Force, recently established in response to the increased global attention to the serious threat of AMR to public health, will develop science-based guidance to enable coherent management of antimicrobial resistance along the food chain.

Other Codex texts on veterinary drugs and their residues, food hygiene, animal feed, also contribute to tackle AMR by preventing the development and minimizing the transmission of AMR through the food chain.

Related Codex Texts

Reference Title Committee Last modified
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CXC 61-2005Code of Practice to Minimize and Contain Foodborne Antimicrobial ResistanceTFAMR2021
CXG 77-2011Guidelines for Risk Analysis of Foodborne Antimicrobial ResistanceTFAMR2021
CXG 94-2021Guidelines on integrated monitoring and surveillance of foodborne antimicrobial resistance TFAMR2021

News

WAAW/ ACT countries acted now to protect our present and secure our future

World Antimicrobial Awareness Week (WAAW) was celebrated 18–24 November 2025, bringing renewed attention to the urgent global challenge posed by antimicrobial resistance (AMR). This year’s theme, “Act Now: Protect Our Present, Secure Our Future”, underscored how AMR is already affecting human, animal and environmental health, and how coordinated, immediate action is essential to preserve the effectiveness of life-saving antimicrobial treatments. AMR is no longer an emerging threat, but a reality. A recent WHO analysis shows that between 2018 and 2023, antibiotic [...]
11 December 2025

ACT / Cambodia strengthens feed inspection capacity to combat antimicrobial resistance

Cambodia is stepping up efforts to curb antimicrobial resistance (AMR) in livestock production by improving the skills of its feed inspectors. From 3–5 December 2025, the Food and Agriculture Organization of the United Nations (FAO), through its Action to Support the Implementation of Codex AMR Texts (ACT) project, and the Ministry of Agriculture, Forestry and Fisheries (MAFF) conducted a Training of Trainers (ToT) on good animal nutrition, feed quality, and feed safety in Phnom Penh. The three-day programme brought together 46 [...]
11 December 2025

Global conference explores sustainable development of food safety beyond antimicrobial resistance

“Sustainable Development of Food Safety Beyond Antimicrobial Resistance (AMR)” was the central theme of discussions at the 5th Global Conference on Foodborne Antimicrobial Resistance (GCFA), held on 16–17 September in Seoul. The GCFA is the only international event dedicated exclusively to this topic and is hosted by the Ministry of Food and Drug Safety of the Republic of Korea, which also supports the FAO-implemented, Action to Support Implementation of Codex AMR Texts (ACT) project. Opening the conference, Minister Oh Yu-kyoung welcomed [...]
19 September 2025

Codex in action: Ulaanbaatar workshop addresses risk communication

 Ulaanbaatar, Mongolia  A risk communication workshop under the Republic of Korea-funded “One Health for Food Safety” (1H4FS) project was held in Ulaanbaatar, Mongolia 4–6 July. The workshop brought together representatives from the Lao People's Democratic Republic, Mongolia, the United Republic of Tanzania and Viet Nam, to strengthen national capacities in risk analysis for food safety. A total of 40 participants from 15 different agencies took part in the event. The workshop was officially opened by T. Jambaltseren, State Secretary of the Ministry [...]
11 July 2025

ACT / Awareness study provides key insights on antimicrobial use and attitudes in Nepal

In Nepal, a recent study with a mixed approach of knowledge, attitude and practice (KAP) and behavioural science among the poultry farmers on antimicrobial use has helped researchers gather data that will help them understand not only where there are gaps in knowledge around antimicrobial resistance (AMR), but also the influences on relevant behaviours that will help authorities support farmers and veterinarians to work towards good practices. The study was carried out under the Action to support implementation of Codex AMR [...]
06 May 2025

ACT / Project review acknowledges progress towards an effective global response to AMR

A consultation meeting, held on 12 March, has heard a report on the progress of the FAO-implemented Action to support implementation of Codex AMR texts (ACT) project over the last year. In the meeting, the ACT project team detailed to representatives from the project donor, the Republic of Korea, the activities and achievements that took place in 2024. The project aims at improving monitoring and surveillance, governance and awareness of foodborne AMR and is being implemented in Bolivia (Plurinational State [...]
13 March 2025
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Key Facts

  • Around 500.000 human deaths each year are related to antimicrobial resistance 
  • 27 different antimicrobial classes are used in animals. 
  • Total global animal health market in 2011 was equivalent to USD 22 billion (OECD) 
  • Only 42 countries have a system to collect data on the use of antimicrobials in livestock (OIE)
  • No standardized data available on the global use of antimicrobials in livestock

Source FAO


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