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Vaccine Manual: the production and quality control of veterinary vaccines for use in developing countries









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    Book (stand-alone)
    Veterinary vaccines: principles and applications 2022
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    Provides a concise and authoritative reference on the use of vaccines against diseases of livestock. Compiled by Senior Animal Health Officers at The Food and Agriculture Organization of the United Nations, and with contributions from international leading experts, Veterinary Vaccines: Principles and Applications is a concise and authoritative reference featuring easily readable reviews of the latest research in vaccinology and vaccine immune response to pathogens of major economic impact to livestock. It covers advice and recommendations for vaccine production, quality control, and effective vaccination schemes including vaccine selection, specifications, vaccination programs, vaccine handling in the field, application, failures, and assessment of herd protection. In addition, the book presents discussions on the current status and potential future developments of vaccines and vaccination against selected transboundary animal diseases.
    • Provides a clear and comprehensive guide on using veterinary vaccines to protect livestock from diseases
    • Teaches the principles of vaccinology and vaccine immune response
    • Highlights the vaccine production schemes and standards for quality control testing
    • Offers easy-to-read reviews of the most current research on the subject
    • Gives readers advice and recommendations on which vaccination schemes are most effective
    • Discusses the today’s state of vaccines and vaccination against selected transboundary animal diseases as well as possible future developments in the field
    Veterinary Vaccines: Principles and Applications is an important resource for veterinary practitioners, animal health department officials, vaccine scientists, and veterinary students. It will also be of interest to professional associations and NGO active in livestock industry.
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    The last hurdles towards Rift Valley Fever control
    Report on the ad hoc workshop on the current state of Rift Valley fever vaccine and diagnostics development – Rome, 5–7 March 2014
    2015
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    In the past decade, tremendous progress has been made in the development of Rift Valley fever (RVF) vaccines, and several next-generation vaccines are currently being evaluated in registration trials. However, due to the sporadic, yet explosive nature of RVF outbreaks, the challenge remains to have these vaccines available at the right time and place. Innovative, appropriate diagnostics will aid in the selection of vaccines and will help to determine when to vaccinate animals. To address these i ssues, the Food and Agriculture Organization of the United Nations (FAO) organized a technical workshop in March 2014. The workshop was supported by the National Center for Foreign Animal and Zoonotic Disease Defense (FAZD) and the United States Centers for Disease Control and Prevention (CDC), in collaboration with representatives of the Central Veterinary Institute, Wageningen University and Research Centre (CVI-WUR), the World Organisation for Animal Health (OIE) and the International Atomic Energy Agency (IAEA). Global experts in RVF vaccine development, leading veterinary vaccine manufacturers and the chief veterinary officers from Egypt, Kenya, Mauritania, Senegal and Sudan attended the meeting. Issues related to the application of classical vaccines in endemic areas were discussed, as well as novel vaccines that are already used in the field or are currently being evaluated in registration trials. These vaccines are expected to fulfil the features related to safety and efficacy recommended in the previous FAO meeting, held in Rome in January 2011. Due to these developments, we have entered a new era in which effective vaccines for the widespread vaccination of livestock will be available. Logistical and political issues are the last major hurdles to RVF control.
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    Book (stand-alone)
    Rift Valley fever vaccine development, progress and constraints
    GF-TADs meeting / November 2010
    2011
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    Rift Valley fever (RVF) is an acute arthropod-borne infection first recognized in Kenya in 1931. Today, the RVF virus has been found in countries across Africa, the Arabian Peninsula and islands in the Indian Ocean, including Madagascar, Comores and Mayotte. This virus has a strong capacity to spread to previously unaffected areas, thanks to its broad host range and ability to be transmitted by at least 30 different mosquito species ¿some of which are found in Europe, Australasia and the America s. Outbreaks following first incursions of RVF can result in explosive epidemics involving both humans and livestock.The control of RVF outbreaks includes vaccination of susceptible animals. Two vaccines are currently available; however, each has significant drawbacks. There is a widely recognized need to develop safer and more efficacious vaccines for animals. Rift Valley fever vaccine development, progress and constraints is the report of an international expert workshop that brought together leading experts and policy-makers in RVF virology, epidemiology and vaccine development. The workshop objective was to gain consensus and make recommendations on the desired features of novel veterinary RVF virus vaccines, and to explore how incentives can be established to assure that these vaccines come to market.

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