This article highlights the challenges of modern global agrifood systems, including climate change, biodiversity loss, and industrial agriculture. It champions agroecology—a holistic approach blending ecological, social, and economic practices—as a solution to building sustainable and resilient food systems. Case studies like Cuba’s Finca del Medio illustrate how agroecological practices can nurture harmony with nature while empowering communities. The article underscores the urgency of systemic collaboration to transform food systems, protect biodiversity, and promote fairness, sustainability, and resilience in addressing global food and climate crises.