This issue brief explores the women-led interventions to transform water security, stewardship, and management underway around the world to better understand the link between water security and gender equality and identify fruitful pathways to achieving both goals. Our analysis demonstrates the costs associated with undervaluing women’s expertise in water management, and the measurable impacts women’s water stewardship can have on peace, prosperity, profitability, and sustainability. Growing this evidence base is critical, because women remain under-represented at all levels of water governance and management, despite playing a crucial role globally in managing household water procurement, especially in under-resourced settings, and environmental stewardship. Much more can be done to leverage women’s expertise to meet the goal of access to safely managed water and sanitation for all.