This document sheds light on the ongoing efforts in Eastern and Southern Africa to develop National Agroecology Strategies (NASs), aiming to transform agri-food systems through the promotion of agroecological production practices, and the development of markets, value chains, and consumer demand. The brief offers an unique insight into policy advancements across Kenya, Malawi, Rwanda, South Africa, Tanzania, Uganda, Zambia, and Zimbabwe, highlighting the burgeoning momentum towards crafting national frameworks that support the agroecological transition of food systems. It addresses critical questions about the nature of NASs, the lessons learned in their development for real impact, the intervention areas they encompass, and the essentials for translating these strategies into tangible, on-the-ground success. Through a peer-to-peer exchange among policymakers and influencers, this outcome brief aims to catalyze a substantial change by fostering a deeper understanding and implementation of agroecological strategies across the region.