How smallholders may contribute to food and nutrition security remains a key challenge in many developing countries. Despite being the main rural actors, smallholders are frequently the most food insecure, given an array of biophysical and socioeconomic challenges that were addressed during the workshop. These proceedings discuss the potential role of smallholders in food security and in poverty reduction. The opportunities and constraints are assessed, by analysing the availability, access and utilisation of production factors. The key message is that enhancing smallholders’ production capacities and their economic and social resilience may have a positive impact on food security and nutrition at different levels. However, not all smallholders are the same, and assistance strategies need to differentiate between smallholders who should be ‘moving up’ into more productive systems and those who should be ‘moving out’ of farming. The choice should depend on the type of constraints smallholders face