Food safety and quality

Food allergens

Certain foods trigger an allergic reaction in some people – a medical condition in which their immune system mistakenly responds as it would to a threat. Approximately 220 million people worldwide have food allergies. The proteins in food that trigger allergic reactions are known as food allergens. A single food item may contain more than one allergen, and people may be allergic to multiple foods.  

Our work

FAO, in collaboration with the World Health Organization (WHO), has convened a series of meetings of the ad hoc Joint FAO/WHO Expert Consultation on Risk Assessment of Food Allergens to update the advice available on this important topic. 

The first meeting of the most recent series of consultations was held in December 2020. Based on the latest scientific evidence, the expert committee identified and used three criteria – prevalence, potency and severity – to assess proteins for their potential inclusion or exclusion on a priority food-allergen list.

In March 2021, the Expert Consultation convened for a second time to establish threshold levels for priority allergenic foods. Through risk assessment, reference doses were recommended based on health-based guidance values for each of the priority allergens.

In October 2021, FAO and WHO reconvened for a third meeting to review and evaluate the evidence in support of precautionary allergen labelling to address unintended allergen presence in foods.

In November 2022, the fourth meeting addressed whether it was scientifically justifiable that foods containing certain ingredients derived from priority allergenic foods (such as highly refined oils) could be exempted from mandatory declaration on packaged foods. 

Why is it important?

The deliberations and conclusions of the recent series of meetings of the ad hoc Joint FAO/WHO Expert Consultation on Risk Assessment of Food Allergens were shared with the Codex Committee on Food Labelling (CCFL) and the Codex Committee on Food Hygiene (CCFH), to support the development of internationally agreed upon food safety standards and guidelines relevant to the management of food allergens. 

FAO continues to work with top experts to evaluate and document the latest science in this field. All conclusions and recommendations are publicly available for policy development, best practices and research.

Reports
Brochures
In brief: Exemptions from mandatory food allergen declaration
2025

For some people, certain foods may trigger an allergic reaction - a medical condition where their immune system mistakenly responds as it would to a...

In brief: Precautionary allergens labelling (PAL)
2025

For some people, certain foods may trigger an allergic reaction - a medical condition where their immune system mistakenly responds as it would to a...

In brief: Priority food allergens
2025

For some people, certain foods may trigger an allergic reaction - a medical condition where their immune system mistakenly responds as it would to a...

In brief: Food allergen reference doses
2025

For some people, certain foods may trigger an allergic reaction - a medical condition where their immune system mistakenly responds as it would to a...

 Join the conversation
Other reports
Other related resources
Other materials
News
05/11/2025
05/11/2025 - Gluten, a group of proteins found in cereals such as wheat, barley and rye, can trigger serious health reactions in people with coeliac disease, even at very low levels. Determining how much gluten can be safely tolerated is critical for protecting public health and guiding accurate food labelling.
17/10/2025
Imagine enjoying a tasty meal or snack, wondering if even the first bite could trigger a life-threatening allergic reaction. That's the reality for millions worldwide, and it's why a recent...
08/10/2025
Food allergens affect millions of people worldwide, posing significant challenges for food safety, consumer protection, and international trade. To help address these challenges, FAO and WHO convened a global Expert...
17/06/2025
Did you know that food allergens are among the leading causes of food-related health risks, particularly for individuals with severe allergic reactions? These allergens, which include ingredients like nuts, soy,...
11/04/2025
Over 220 million people globally live with food allergies, making clear and accurate food labelling essential. Traditionally, food allergen management has relied on a hazard-based approach, where even the mere...
11/03/2025
Food allergies affect over 220 million people worldwide, underscoring the need for efficient and safe management strategies. Traditionally, allergen labelling has followed a precautionary hazard-based approach, where even the slightest...