DAS-Ø1131-3
Commodity:
Corn / Maize
Traits:
Resistance to diseases and pests > Insects > Lepidoptera
Resistance to herbicides > Other modes of action > Glyphosate
Australia
Country profileName of Product Applicant:
Corteva AgriScience Australia
Application Summary:
Food Standards Australia New Zealand (FSANZ) received an application from Corteva Agriscience Australia Proprietary Limited to vary Schedule 26 in the Australia New Zealand Food Standards Code (the Code). The variation is to include food from a new genetically modified (GM) corn line DAS1131, with the OECD Unique Identifier DAS-Ø1131-3. This corn line is tolerant to the herbicide glyphosate and protected against lepidopteran insect pests.
Protection against lepidopteran insect pests is conferred by the expression of the insecticidal cry1Da2 gene encoding the Cry1Da2 protein. The cry1Da2 gene is composed of two sequences from Bacillus thuringiensis: (1) the insecticidal core toxin sequence of the cry1Da2 gene; and (2) a segment of the cry1Ab gene.
Tolerance to the herbicide glyphosate is achieved by the expression of the dgt-28 epsps gene encoding the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (DGT-28 EPSPS) from Streptomyces sviceus. The DGT-28 EPSPS protein is fused to TraP8, a chimeric chloroplast transit peptide derived from Brassica napus and Brassica rapa, enabling targeting to the chloroplast.
Many different Cry and EPSPS proteins are found in a variety of different GM crops grown around the world (FAO 2023; ISAAA 2023). FSANZ has assessed and approved 29 applications where Cry proteins have been introduced into crops for pest protection and 25 applications where EPSPS proteins have been used in crops for herbicide-tolerance. Crop species with Cry and EPSPS proteins that FSANZ has assessed and approved include corn, cotton, potato and soybean. A1280 is the first application to assess the specific Cry and EPSPS proteins, Cry1Da2 and DGT-28 EPSPS.
If approved, food derived from DAS1131 corn line may enter the Australian and New Zealand food supply as imported food products.
Authorization Date:
22/07/2024
Authorization Scope:
Food
Safety Assessment Summary:
Please see link below to A1280_Risk assessment supporting document.
Detection Method:
Relevant Links:
Authorization expiration date, if any:
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United States of America
Country profileName of Product Applicant:
Pioneer Hi-Bred International, Inc.
Application Summary:
BNF No. 191CornDAS1131DAS-Ø1131-3
Developer: Pioneer Hi-Bred International, Inc.8325 NW 62nd AvenueJohnston, IA 50131
Trait(s): Insect resistanceHerbicide tolerance (glyphosate)
Submission Date : Jan 26, 2022
Introduced Protein: Cry1Da2 protein(source): Bacillus thuringiensis
Introduced Protein 2: DGT-28 EPSPS protein
(source): Streptomyces sviceus
Authorization Date:
12/12/2023
Authorization Scope:
Food and feed
Safety Assessment Summary:
Please consult the website links below.
Detection Method:
Authorization expiration date, if any:
Relevant documents upload:
Malaysia
Country profileName of Product Applicant:
Corteva Agriscience (Malaysia) Sdn. Bhd.
Application Summary:
Please refer to the decision document of the National Biosafety Board
Authorization Date:
18/04/2025
Authorization Scope:
Food and feed
Safety Assessment Summary:
Please refer to the Risk Assessment Report
Detection Method:
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Authorization expiration date, if any:
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Japan
Country profileName of Product Applicant:
Corteva Agriscience Japan Limited
Application Summary:
Maize resistant to lepidopteran insect pests and tolerant to herbicide glyphosate (DAS1131)
Authorization Date:
24/10/2024
Authorization Scope:
Food
Safety Assessment Summary:
The FSCJ concluded that maize resistant to lepidopteran insect pests and tolerant to herbicide glyphosate (DAS1131) is unlikely to pose concerns relevant to human health.
Please refer to the link below for details.
Detection Method:
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Brazil
Country profileName of Product Applicant:
Corteva Agriscience do Brasil Ltda.
Application Summary:
Commercial Release of corn DAS-Ø1131-3 (OECD Unique Identifier referred to as corn DAS1131) has been genetically modified to express the Cry1Da2 protein that confers protection against certain susceptible lepidopteran pests and the DGT-28 EPSPS protein that confers tolerance to the herbicide glyphosate
Authorization Date:
01/02/2024
Authorization Scope:
Food and feed
Safety Assessment Summary:
The biosafety data for genetically modified corn DAS-Ø1131-3 meets the relevant standards and legislation that aim to guarantee the biosafety of the environment, agriculture, human and animal health. The request for exemption from post-commercial release monitoring is granted. This activity does not potentially cause significant degradation of the environment or human health.
Detection Method:
Molecular traditional methods.
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Authorization expiration date, if any:
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Canada
Country profileName of Product Applicant:
Pioneer Hi-Bred Canada Company
Application Summary:
Pioneer Hi-Bred Canada Company has developed a genetically modified (GM) maize line (Zea mays L.), DAS1131-3, that exhibits resistance to Lepidopteran maize pests and tolerance to glufosinate-ammonium herbicide. The insect resistance trait was achieved through expression a novel chimeric cry1DA2 gene protein. The tolerance to glyphosate herbicide trait was achieved through expression of a chimeric dgt-28 epsps gene.
Authorization Date:
04/09/2024
Authorization Scope:
Food and feed
Safety Assessment Summary:
Please see the decision document weblinks.
Detection Method:
Relevant Links:
Authorization expiration date, if any:
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