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A one health priority research agenda for antimicrobial resistance

Antimicrobial resistance (AMR) has been recognized as one of the greatest global threats to humans, animals, plants and ecosystems health threatening the achievement of the Sustainable Development Goals. In our globally connected world, resistance to antimicrobials may spread and circulate among humans, animals, plants and the environment, necessitating a “One Health” approach.

While the One Health approach is relevant to all efforts to prevent and control AMR, this priority research agenda focuses on research areas at the interface between sectors.

This research agenda is a joint product of the Quadripartite organizations –FAO, UNEP, WHO and WOAH - and a result of extensive stakeholder and expert engagement. A structured mixed-methods approach was used including reviews of academic and grey literature, online open global survey, and consensus exercise by modified Delphi method in which global experts prioritized research areas for the five pillars: transmission, integrated surveillance, interventions, behavioral insights and change, and economics and policy. We hope this research agenda will serve as a guiding tool for countries, research institutes and funding bodies to support for One Health AMR research, helping policymakers, researchers and the multidisciplinary scientific community to work together across sectors on solutions that will prevent and mitigate AMR on a national, regional and global scale as further evidence on research strategies, interventions and policies is required to understand what works, in which contexts and for whom.

Policy Theme