AVIAN INFLUENZA VACCINES |
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Click on the country you want to find information on available vaccines: China - France - Netherlands -Pakistan - Indonesia - Mexico - USA - Italy - Germany. |
Compiled by FAO’s Emergency Prevention System
for Transboundary Animal and Plant Pests and Diseases (EMPRES).
The manufacturers/suppliers and their vaccines are not necessarily endorsed by FAO
and it is the [importing] country's responsibility to establish independent
quality assurance/quality control for safety, purity, potency, and efficacy parameters. |
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Laboratory |
Affiliation |
Location |
Strain |
Type |
Antibody levels |
Established Production |
Website |
Comments |
Harbin Veterinary Research Institue |
Harbin, Heilongjiang province |
A/Turkey/England/N-28/73 |
Inactivated monovalent |
8log2 reached by the fifth week after vaccination and maintained for 4 weeks, protective antibody titers maintained for 23 weeks |
Dec. 2003 |
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Harbin Veterinary Research Institue |
Harbin, Heilongjiang province |
A/Goose/Guandong/1996, Subtype H5N1, Low pathogenicity |
Inactivated monovalent |
Used for ducks and other waterfowl in Vietnam |
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Harbin Veterinary Research Institue |
Harbin, Heilongjiang province |
A recombinant virus from A/Goose/Guangdong/1996 and human influenza vaccine virus H5N1 |
Inactivated recombinant |
9log2 reached by the third week after vaccination and maintained for 4 weeks, protective antibody titers maintained for 25 weeks |
Jan. 2005 |
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High specificity, antibody level and long maintain time, vaccinated water fowl do not shed virus and are resistant against infection proved by the laboratory results |
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Harbin Veterinary Research Institue |
Harbin, Heilongjiang province |
A recombinant avian pox virus expressed H5 from A/Goose/Guangdong/1996 |
Live recombinant avian pox virus vectored H5 |
7log2 reached by the second week after vaccination protective antibody titers maintained for26 weeks |
Jan. 2005 |
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Induced only antibody against specific protein, helpful in differentiation of the immune and the infection. The immune efficiency is less than the other two vaccines, and price is higher. Only for chicken |
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Zhengzhou Bio-pharm Co. Ltd |
China Animal Husbandry Group |
Zhengzhou City, Shandong province |
A/Turkey/England/N-28/73 |
Inactivated monovalent |
8log2 reached by the fifth week after vaccination and maintained for 4 weeks, protective antibody titers maintained for23 weeks |
Dec. 2003 |
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Qingdao Yebio Bioengineering Co. Ltd |
National Animal Quarantine Institute of the Ministry of Agriculture |
Qingdao City, Shandong province |
A/Turkey/England/N-28/73 |
Inactivated monovalent |
8log2 reached by the fifth week after vaccination and maintained for 4 weeks, protective antibody titers maintained for 23 weeks |
Dec. 2003 |
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Qingdao Yebio Bioengineering Co. Ltd |
National Animal Quarantine Institute of the Ministry of Agriculture |
Qingdao City, Shandong province |
H9 |
Inactivated |
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Qingdao Yebio Bioengineering Co. Ltd |
National Animal Quarantine Institute of the Ministry of Agriculture |
Qingdao City, Shandong province |
H5N2/H9 |
Inactivated bivalent |
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Guangdong Yongshun Bio-pharm Co.Ltd |
Guangdong province |
A/Turkey/England/N-28/73 |
Inactivated monovalent |
8log2 reached by the fifth week after vaccination and maintained for 4 weeks, protective antibody titers maintained for23 weeks |
Dec. 2003 |
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Zhaoqing Dahua agriculture Bio-pahrm Co.Ltd |
Veterinay College of Southern China Agriculture University |
Zhaoqing City, Guangdong |
A/Turkey/England/N-28/73 |
Inactivated monovalent |
8log2 reached by the fifth week after vaccination and maintained for 4 weeks, protective antibody titers maintained for23 weeks |
Dec. 2003 |
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Liaonong Yikang Bioengineering Co.Ltd |
Liaoyang City, liaoning Province |
A/Turkey/England/N-28/73 |
Inactivated monovalent |
8log2 reached by the fifth week after vaccination and maintained for 4 weeks, protective antibody titers maintained for23 weeks |
Dec. 2003 |
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Nanjing Merial Animal Products Co., Ltd |
China Animal Husbandry Group |
Nanjing City, Jiangsu province |
A/Turkey/England/N-28/73 |
Inactivated monovalent |
8log2 reached by the fifth week after vaccination and maintained for 4 weeks, protective antibody titers maintained for23 weeks |
Dec. 2003 |
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Qilu Animal Health Products Factory |
Ji'nan City, Shandong province |
A/Turkey/England/N-28/73 |
Inactivated monovalent |
8log2 reached by the fifth week after vaccination and maintained for 4 weeks, protective antibody titers maintained for23 weeks |
Dec. 2003 |
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Chengdu Jianghua Bioproducts Co.Ltd |
Jianghua Group |
Ziyang City, Sichuan province |
A/Turkey/England/N-28/73 |
Inactivated monovalent |
8log2 reached by the fifth week after vaccination and maintained for 4 weeks, protective antibody titers maintained for23 weeks |
Dec. 2003 |
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Merial International Trading Company |
Merial (France) |
H5N2 |
Inactivated monovalent |
Commercial name: FLU H5N2 Formalin inactivated. Mineral oil adjuvant |
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Laboratory |
Affiliation |
Location |
Strain |
Type |
Antibody levels |
Established Production |
Website |
Comments |
Merial |
H9N2 or H7N1 (Some H7N3) strains as separate vaccine |
Inactivated monovalent |
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Merial |
A/chicken/Italy/1067/99 (H7N1) and A/chicken/Italy/22A/98 (H5N9) |
Inactivated bivalent |
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Commercial name: BioFlu H7N1 and H5N9 For chicken |
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Merial |
H5 from A/Turkey/Ireland/83 recombinant Fowlpox vector |
Recombinant live |
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Commercial name: Trovac AIV, H5. Protection after day old vaccination birds up until 20 weeks of age. The vaccines is produced in USA |
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Laprovet S.A.S. |
Tours, Cedex 2, France |
H5N2 |
Inactivated Monovalent |
Commercial name: ITA-FLU. Formalin inactivated. Mineral oil adjuvant. The vaccine is produced in MEXICO. |
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Ceva Santé Animale SA |
Libourne, France |
A/Chicken/Mexico/232/94/CPA H5N2 Oil emusified. |
Inactivated Monovalent |
8Log 2.Four weeks after vaccination at 10 days/Subcutaneous. |
Approved 2004 |
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Commercial name: FLU-KEM. Binary ethyleneimine inactivated. Mineral oil adjuvant. The vaccine is produced in MEXICO through CEVA de MEXICO |
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Laboratory |
Affiliation |
Location |
Strain |
Type |
Antibody levels |
Established Production |
Website |
Comments |
Intervet International b.v. |
Boxmeer, Netherlands |
A/Chicken/Mexico/232/94/CPA (H5N2 or H5N6) |
Inactivated |
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Commercial name: Nobilis Influenza H5N2 or Nobilis Influenza H5N6. Formalin or beta-propriolactone inactivated. Mineral oil adjuvant. The vaccine is produced in MEXICO and SPAIN. |
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Intervet |
A/CK/Italy/473/99 (H7N1) |
Inactivated |
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Commercial name: Nobilis Influenza H7N1. Oil adjuvant. |
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Intervet |
A/duck/Potsdam/15/80 (H7N7) |
Inactivated |
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Commercial name: Nobilis Influenza H7N7 |
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Laboratory |
Affiliation |
Location |
Strain |
Type |
Antibody levels |
Established Production |
Website |
Comments |
Sindh Vaccine Production Centre |
Karachi, Pakistan |
H7N3 and H9N2 strains, separate or combined products |
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Biolab (pvt) Ltd |
Rawalpindi, Pakistan |
H7N3 and H9N2 strains for both separate and combined products |
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Avicina Laboratories |
Lahore, Pakistan |
H7N3 and H9N2 strains for both separate and combined products |
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Otoman Pharma |
Lahore, Pakistan |
H7N3 and H9N2 strains for both separate and combined products |
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Laboratory |
Affiliation |
Location |
Strain |
Type |
Antibody levels |
Established Production |
Website |
Comments |
Medion |
Indonesia |
H5N1 |
Inactivated |
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Commercial name:Medivac AI |
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Laboratory |
Affiliation |
Location |
Strain |
Type |
Antibody levels |
Established Production |
Website |
Comments |
Intervet |
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Mexico City |
A/Chicken/Mexico/232/94/CPA (H5N2) |
Inactivated Monovalent |
8log 2. Four weeks after vaccination at 10 days of age/Subcutaneous |
Approved 2004 |
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Intervet Mexico |
Intervet (Netherlands) |
Huixquilucan |
H5N2 or H5N6 |
Inactivated Monovalent |
Commercial name: Nobilis influenza H5. Mineral oil adjuvant. The same vaccine is supplied by Intervet international b.v. in NETHERLANDS |
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Boheringer Ingelheim Vetmedica, S.A. de C.V. |
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Guadalajara, Jalisco |
A/Chicken/Mexico/232/94/CPA (H5N2) |
Inactivated Monovalent |
8Log 2.Four weeks after vaccination at 10 days/Subcutaneous. |
Approved 2004 |
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Mineral oil adjuvant. This same vaccine produced in MEXICO is supplied in GERMANY through Boehringer Ongelheim Vetmedica GmBH |
Avimex laboratories |
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Mexico City |
A/Chicken/Mexico/232/94/CPA (H5N2) |
Inactivated Monovalent |
8Log 2.Four weeks after vaccination at 10 days/Subcutaneous. |
Approved 2004 |
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Investigación Aplicada S.S. (IASA) |
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Tehuacan, Puebla |
A/Chicken/Mexico/232/94/CPA (H5N2) |
Inactivated Monovalent |
8Log 2.Four weeks after vaccination at 10 days/Subcutaneous. |
Approved 2004 |
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Ceva de Mexico |
Ceva Santé Animale SA (France) |
Mexico City |
A/Chicken/Mexico/232/94/CPA (H5N2) |
Inactivated Monovalent |
8Log 2.Four weeks after vaccination at 10 days/Subcutaneous. |
Approved 2004 |
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Commercial name: FLU-KEM. Mineral oil adjuvant This vaccine is supplied in FRANCE through CEVA Santé Animale |
Ceva de Mexico |
Ceva Santé Animale SA (France) |
Mexico City |
A/Chicken/Mexico/232/94 (H5N2+La SotaNDV) |
Inactivated Bivalent |
Commercial name: NEW-FLU-KEM |
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All these five mexican labs produce & sell a bivalent vaccine Avian Influenza + Newcatle Disease |
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Laboratory |
Affiliation |
Location |
Strain |
Type |
Antibody levels |
Established Production |
Website |
Comments |
Biomune vaccines |
Ceva Santé Animale SA |
Lenexa - Kansas USA |
A/Turkey/Wisconsin/68 (H5N9) |
Inactivated |
Commercial name: Layermune AIV H5N9. Beta-propriolactone inactivated. Mineral oil adjuvant. |
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A/Chicken/New York/273874/03 (H7N2) |
Inactivated |
Commerical name: Layermune AIV H7N2 |
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A/Turkey/Utah/24721-10/95 (H7N3) |
Inactivated |
Commercial name: Layermune AIV H7N3 |
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Fort Dodge Animal Health |
Overland Park, USA |
H5N3 |
Inactivated |
Commercial name: Poulvac Flu Fend I H5N3 RG Formalin inactivated. Water in oil adjuvant |
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Fort Dodge Animal Health |
Overland Park, USA |
H5N3 |
Inactivated |
Commercial name: Inactivated AIV type A, H5N2, H5N9, H7N2, H7N3 Formalin inactivated. Water in oil adjuvant. |
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Laboratory |
Affiliation |
Location |
Strain |
Type |
Antibody levels |
Established Production |
Website |
Comments |
Merial Italy Spa |
Merial (France) |
Italy |
H5N9 |
Inactivated monovalent |
Minimum HI antibody response of 1:32 in vaccinated birds |
Commercial name: Gallimune Flu H5N9. Beta-propriolactone inactivated. Mineral oil adjuvant. |
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Laboratory |
Affiliation |
Location |
Strain |
Type |
Antibody levels |
Established Production |
Website |
Comments |
Boheringer Ingelheim Vetmedica, GmBH |
Ingelheim am Rehin, Germany |
H5N2.A/Chicken/Mexico/232/94/CPAOil emusified |
Inactivated Monovalent |
8Log 2.Four weeks after vaccination at 10 days/Subcutaneous. |
Mineral oil adjuvant. * The vaccine is produced in MEXICO by Boehringer Ingelheim Vetmedica S.A. de C.V. |
* Supplier company |
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