#108 Method of manufacture (starting materials, pathways, by-products and impurities)
OECD data point number
IIA 1.8 (Chemical pesticides – active ingredient)
IIP 1.8 (pheromones and other semiochemicals – active ingredient)
Circumstances in which the data are required
The information is always required.
Test substance
Information to be provided for: technical grade active ingredient (TGAI)
Typical information to be provided by the applicant
IIA 1.8.1 / IIP 1.8.1: The method of manufacture, in terms of the chemical pathways involved, and the identity of by-products and impurities present in the final product, should be provided, for each manufacturing plant.
IIA 1.8.2 / IIP 1.8.2: A description of the identity of the starting materials should be provided
Where the information provided relates to a pilot plant production system, the information required should again be provided once industrial scale production methods and procedures have stabilized.
Guidelines
Chemical pesticides
- US EPA Product Properties Test Guidelines. OPPTS 830.1620. Description of production process
- US EPA Product Properties Test Guidelines. OPPTS 830.1670. Discussion of formation of impurities
- US EPA Product Properties Test Guidelines. OPPTS 830.1600. Description of materials used to produce the product
BioChemical pesticides
- US EPA Biochemicals Test Guidelines. OPPTS 880.1200. Description of starting materials, production, and formulation process.
- US EPA Biochemicals Test Guidelines. OPPTS 880.1400. Discussion of Formation of Impurities