Section 1. General overview of the JECFA process
13/05/2024
This guidance document provides a high-level summary of the entire JECFA veterinary drug residue risk assessment process, with each step described in greater detail in subsequent sections.
Veterinary drug residues from animal-derived food products may pose risks to human health. To perform a drug residue risk assessment, we must first characterize the risk by evaluating the hazard and assessing exposure.
Consult the guidance document for a brief description of the relevant data necessary for the evaluation process, followed by the key outcomes and relevant JECFA experts responsible along each step of the JECFA risk assessment process:
- Hazard assessment: Derivation of health-based guidance values (HBGVs) such as acceptable daily intake (ADI) and acute reference dose (ARfD);
- Residue assessment: Total residue (TR) and marker residue (MR) depletion in edible tissues;
- Exposure assessment: Use of the global estimated chronic or acute dietary intake; and
- How maximum residue limits (MRLs) are derived as the final step of the JECFA risk assessment process.