Section 4.2. Estimating dietary exposure using GECDE and GEADE
13/05/2024
This guidance document explains how JECFA estimates dietary exposure to veterinary drug residues using global estimated chronic/acute dietary exposure.
JECFA uses a novel, data-driven process for predicting the amounts of animal-derived food products consumed by people. This process has significant impacts on the resulting drug residue exposure assessment.
In this guidance document you will:
- learn about the food intake processes used by JECFA and their use in the subsequent exposure estimates (global estimated chronic/acute dietary exposure; GECDE/GEADE); and
- incorporate residue depletion data (average or high-level residues) from animal-derived food products with dietary food intake estimates to predict acute (GEADE) and chronic (GECDE) exposure to veterinary drug residues, using the skills learned in Section 3.