27 August 2026, 08:30 hours; Rome
This update covers avian influenza viruses (AIV) with zoonotic potential occurring worldwide, i.e. H5Nx, H7Nx high pathogenicity avian influenza (HPAI) viruses and H3N8, H5Nx, H6N1, H7Nx, H9N2, H10Nx and H11 low pathogenicity avian influenza (LPAI).
Specific information is available for Avian Influenza A(H7N9) virus viruses and Sub-Saharan Africa HPAI in related FAO Avian Influenza situation updates.
HPAI outbreaks in animals officially reported since last update (23 July2026): in total, 574 outbreaks / events have been reported in 22 countries/territories caused by H5Nx (371), H5N1 (195), H5N5 (1), H7N3 (1) and HxNx (6) (see Table 1 for details).
LPAI events in animals officially reported since the last update: 0 new events were reported.
Number of human cases officially reported since the last update: 9 new events were reported. [ref1, ref2, ref3]
Map 1. Global distribution of AIV with zoonotic potential observed since 1 October 2025 (i.e. current wave)

Symbols may overlap for events in similar geographic locations.
Notes: Refer to the disclaimer available on this webpage for the names and boundaries in this map. The final boundary between the Sudan and South Sudan has not yet been determined. The final status of the Abyei area is not yet determined. The dotted line represents approximately the Line of Control in Jammu and Kashmir agreed upon by India and Pakistan. The final status of Jammu and Kashmir has not yet been agreed upon by the parties.
Source: United Nations Geospatial. 2020. Map of the World. [Cited August 2026]. Modified with GLW 4 data and Emergency Prevention System Global Animal Disease Information System (EMPRES-i), WOAH and National Authorities data, 2025.
Map 2. Global distribution of AIV with zoonotic potential* observed in the period 1 October 2024 to 30 September 2025 (i.e. previous wave)

Symbols may overlap for events in similar geographic locations.
Notes: Refer to the disclaimer available on this webpage for the names and boundaries in this map. Final boundary between the Sudan and South Sudan has not yet been determined. Final status of the Abyei area is not yet determined.
Dotted line represents approximately the Line of Control in Jammu and Kashmir agreed upon by India and Pakistan. The final status of Jammu and Kashmir has not yet been agreed upon by the parties.
Source: United Nations Geospatial. 2020. Map of the World. [Cited October 2025]. Modified with GLW 4 data and Emergency Prevention System Global Animal Disease Information System (EMPRES-i), WOAH and National Authorities data, 2025.
October – December 2024

January – March 2025

April – June 2025

July – September 2025

Symbols may overlap for events in similar geographic locations.
Notes: Refer to the disclaimer available on this webpage for the names and boundaries in this map. Final boundary between the Sudan and South Sudan has not yet been determined. Final status of the Abyei area is not yet determined. Dotted line represents approximately the Line of Control in Jammu and Kashmir agreed upon by India and Pakistan. The final status of Jammu and Kashmir has not yet been agreed upon by the parties.
Source: United Nations Geospatial. 2020. Map of the World. [Cited October 2025]. Modified with GLW 4 data and Emergency Prevention System Global Animal Disease Information System (EMPRES-i), WOAH and National Authorities data, 2024.
Table 1. High pathogenicity avian influenza viruses with zoonotic potential reported since the last update
| Virus | Country/Area | Last observed outbreak | # events reported since the last update | Total # events reported since 1 Oct. 2025 | Species affected since the last update |
|---|---|---|---|---|---|
H5 | Australia | 24/08/2026 | 271 | 271 | Australasian Gannet Australian Magpie, Australian Raven, Black-faced Cormorant, Brown skua, Fluttering Shearwater, Giant Petrel, Greater Crested Tern, Hutton's Shearwater, Little Penguin, Little Raven, Northern Giant Petrel, Pacific Gull, Peregrine Falcon, Raven sp., Silver Gull, Southern Giant Petrel (?), White-fronted Tern, White-headed Petrel; New Zealand (Long-nosed) Fur Seal |
New Zealand | 21/08/2026 | 1 | 1 | Northern giant petrel | |
United States of America7 | 19/08/2026 | 99 | 1771 | American crow, Bald eagle, Barred owl, Black vulture, Blue-winged teal, Cackling goose, Canada goose, Common eider, Cooper's hawk, Eurasian collared dove, Goose, Great black-backed gull, Herring gull, Hooded merganser, Killdeer, Mallard, Northern pintail, Pelican, Peregrine falcon, Red-shouldered hawk, Red-tailed hawk, Rock pigeon, Snow goose, Swainson's hawk, Turkey vulture | |
H5N1 | Australia | 02/08/2026 | 53 | 70 | Silver Gull, Southern Giant Petrel, Northern Giant Petrel, Procellariidae, Brown skua, Greater Crested Tern |
Brazil | 04/08/2026 | 1 | 7 | White-faced Whistling-Duck | |
Chile | 15/06/2026 | 10 | 47 | Non-poultry birds | |
China | 08/08/2026 | 1 | 39 | Chicken | |
Denmark | 17/08/2026 | 1 | 262 | Western Marsh Harrier | |
Ecuador | 09/07/2026 | 1 | 1 | Peruvian pelican | |
Finland | 28/07/2026 | 1 | 39 | Canada Goose | |
Germany | 28/07/2026 | 1 | 4132 | Turkey | |
India | 02/04/2026 | 6 | 46 | Poultry | |
Netherlands (Kingdom of the) | 06/08/2026 | 13 | 484 | Black-headed Gull, Canada Goose, Caspian Gull, Common Tern, Eurasian oystercatcher, Great Crested Grebe, Greylag Goose, Mallard, Mute Swan | |
Norway | 19/08/2026 | 6 | 77 | Cygnus, Greylag Goose, Herring Gull, Mute Swan, Pink-footed Goose | |
Peru | 22/07/2026 | 44 | 93 | Andean Goose, Guanay Cormorant, Peruvian Booby, Peruvian Pelican, Sooty Shearwater, White-cheeked Pintail | |
Portugal | 10/08/2026 | 1 | 34 | Yellow-legged Gull | |
The Philippines | 31/07/2026R | 1 | 22 | Chicken | |
Sweden | 14/08/2026 | 3 | 133 | Poultry; Goosander, Canada Goose | |
United Kingdom of Great Britain and Northern Ireland | Week 34 | 2 | 867 | Canada Goose, Laridae | |
United States of America7 | 20/08/2026R | 26 | 3231 | Turkey, WOAH Poultry, WOAH Non-Poultry; Bald eagle, Common murre, Rock pigeon; American mink (captive), Cat, Cattle, Striped skunk | |
Viet Nam | 19/08/2026 | 24 | 110 | Chicken, Duck, Muscovy duck | |
H5N5 | Norway14 | Jine 202614 | 1 | 3 | Polar bear |
H7N3 | Mexico | 23/06/2026 | 1 | 9 | Plain chachalaca |
HxNx | Honduras | 22/07/2026 | 1 | 8 | Black Vulture |
Indonesia | July 2026 | 5 | 14 | Chicken, duck |
Data was retrieved from WOAH WAHIS portal and Sharing other important animal health information with WOAH page [link], government websites. Data cutoff time: reported on 27 August 2026, 8:30 CEST. $:estimate. ‡: date of confirmation, R: reported date, §: counting Izumi Wintering Habitat of Cranes (Ramsar) as 1 event. Notes: Only those reporting events in animals since the last update are listed in the table. Codes: D:domestic, C:captivity, W:Wild birds, DF: Dairy farm, E:Environment, M: mammalian species other than humans. For more information, consult dedicated webpage of the: 1: British Antarctic Survey (BAS) [link], 2: Australian Government [link], 3: Canada Food and Inspection Agency dashboard [link], 4: TierSeuchenInformationsSystem - Friedrich-Loeffler-Institut [link], 5: Ministry of the Environment [link] 6: Animal and Plant Health Agency (APHA) [link], 7: USDA Animal and Plant Health Inspection Service (USDA/APHIS) [link], 8: Scientific Committee on Antarctic Research (SCAR) [link], 9: The Philippines: Bureau of Animal Industry [link], 10: Brazil: Ministério da Agricultura e Pecuária [link], 11: Indonesia: Laporan Perkembangan Avian Influenza – HPAI [link]. 12: Chile SAG dashboard [link]. 13: Argentina Senasa [link]. 14: Veterinærinstitutte [link]. Bold: the first report of infection in the species. The full list of bird and mammalian species affected by H5Nx HPAI are here.
Domestic
Risk assessment of transmission of highly pathogenic avian influenza H5 viruses into French broiler and layer farms from other poultry sectors. Prev Vet Med, 256:106981. [reference]
Aerosol transmission of infectious diseases in poultry: microbiology, pathogenesis, and control measures. Front Microbiol, 17:1886873. [reference]
Biosecurity deficiencies in HPAI-affected poultry farms in Korea, 2020/2021-2024/2025 seasons. Front Vet Sci, 13:1863522. [reference]
Detection of H5N1 HPAIV Clade 2.3.4.4b Avian Influenza Virus in Backyard Chickens in Costa Rica. Viruses, 18(7):799. [reference]
Genetic and Epidemiological Evidence of Avian Influenza A(H9N2) Detection Among Poultry in Ghana, 2022. Viruses, 18(7):725. [reference]
Regulatory Implications and Control Measures for Lumpy Skin Disease, Highly Pathogenic Avian Influenza, and Foot-and-Mouth Disease in European Livestock. Viruses, 18(7):777. [reference]
Wild
Long-Term Monitoring of Influenza A Viruses in Wild Waterfowl: Evidence from the Lake Baikal Basin (2018-2024). Viruses, 18(7):761. [reference]
Expert Commentary: What do we know about H5 bird flu? [reference]
Genomic and Clinicopathological Characterization of a Reassortant HPAI H5N1 (Clade 2.3.4.4b) in an Endangered Cinereous Vulture (Aegypius monachus) in South Korea, 2026. Transbound Emerg Dis, 2026, 2623621, 15 pages. [reference]
Emerging threat of avian influenza to the world's vultures. Conservation Biology, e70372. [reference]
Clade 2.3.4.4b H5N1 highly pathogenic avian influenza detected in wild bird feces, Eastern Mongolia, 2024. J Vet Sci, 27(4):e38. [reference]
Evolving dynamics of H5Nx avian influenza in China revealed by long-term wild bird surveillance. Nat Commun, 17(1):9011. [reference]
Global dynamics of avian influenza: a twenty-year analysis of highly pathogenic viruses linking the Caspian Basin, Eurasia and Africa sectors (2005-2025). Front Cell Infect Microbiol, 16:1795327. [reference]
Genetic Determinants Analysis of PB1 and PB2 Genes in H5N1 Avian Influenza Strains from Romania. Pathogens, 15(7):768. [reference]
Multiple introductions of highly pathogenic avian influenza viruses into the High Arctic: Svalbard and Jan Mayen, 2022-2025. J Gen Virol, 107(8):002305. [reference]
Spatiotemporal dynamics and ecological risk factors of high pathogenic avian influenza A(H5N1) in Canadian wildlife: A One Health surveillance analysis. Comp Immunol Microbiol Infect Dis, 129:102499. [reference]
Highly Pathogenic Avian Influenza H5N1 in South America, 2022-2025: Spread, Affected Species, and Southward Expansion into the Antarctic Region. Viruses, 18(7):764. [reference]
Skuas as sentinels of high pathogenicity avian influenza H5N1 on the Antarctic Peninsula in the 2024/2025 austral summer. Microb Genom, 12(8):001724. [reference]
Transboundary Spread and Ecological Drivers of HPAI H5N1 Clade 2.3.4.4b During the 2022-2023 Outbreak in Chile: An Integrated Genomic and Spatial Epidemiology Framework. Transbound Emerg Dis, 2026(1):e1266281. [reference]
Genomic Surveillance Uncovers the Silent Spread of Avian Influenza Virus (H5N1 2.3.4.4b) Among Wild Birds and Mammals Along Brazil's Southern Coast. Viruses, 18(7):738. [reference]
Detection of H5N1-Related PB1 Sequences in a Low Pathogenic H11N2 Virus from South American Migratory Shorebirds. Viruses, 18(7):710. [reference]
Emerging threat of avian influenza to the world's vultures. Conserv Biol, 2026 Aug 19:e70372. [reference]
Avian influenza amplified age-related mortality in a long-lived seabird. Nat Commun, 17(1):8653. [reference]
Mammal
Enhanced Pathogenicity and Contact Transmissibility of Human-origin Avian Influenza H5N1 Clade 2.3.4.4b Genotype B3.13 Compared to D1.1 in Ferrets. BioRxiv, 2026 Aug 17:2026.08.10.744032 [reference] Preprint
Neuropathology, novel tissue tropism, and evidence of vertical transmission in South American pinnipeds naturally infected with high pathogenicity avian influenza H5N1 virus in Argentina.Vet Pathol, 2026 Aug 3:3009858261465443. [reference]
Evolution of swine influenza surveillance and one health governance in Taiwan: from zoonotic risk management to integrated preparedness. Vet Res Commun, 50(5):475. [reference]
Identification and characterization of PB2 mutations associated with mammalian adaptation of highly pathogenic H5N1 avian influenza viruses. Front Microbiol, 17:1867604. [reference]
Heterogeneous viral-host response at single-cell resolution and viral adaptive mutational atlas in birds and mammals upon H5 influenza virus infection. Natl Sci Rev, 13(14):nwag380. [reference]
Dairy
Evaluation of serologic assays for detection and quantification of influenza antibodies in milk samples from H5N1 highly pathogenic avian influenza virus infected dairy cows. Front Vet Sci, 13:1902594. [reference]
Seroprevalence of Influenza A(H5N1) Virus in Domestic Cats at Epicenter of Dairy Cattle Outbreaks, California, USA, 2024-2026. Emerg Infect Dis, 32(9). [reference]
Long-term milk-yield impact and recovery in HPAI-affected cows across consecutive lactations and its association with antibody response. J Dairy Sci, 2026 Jul 27:S0022-0302(26)03149-8. [reference]
Acquisition of specific human respiratory tract binding by 2.3.4.4b H5N1 hemagglutinins requires multiple mutations. J Virol, 2026 Aug 10:e0106526. [reference]
Standing HA phenotypic breadth shapes H5N1 cross-host potential. Res Sq, rs.3.rs-10349790. [reference] Preprint
Viruses
Influenza. Nat Rev Dis Primers, 12(1):51. [reference]
Deciphering viral action on host genome structure: a computational physics perspective. Biochim Biophys Acta Mol Basis Dis, 1872(8):168394. [reference]
Complete coding sequence of influenza A virus subtype H1N3 from guinea fowl in Republic of Serbia. Microbiol Resour Announc, 2026 Jul 29:e0021326. [reference]
The emergence of novel H3N8 and H3N3 avian influenza viruses in chickens during multi-province surveillance in China and their potential public health risk. Vet J, 318:106789. [reference]
Risk assessment of avian influenza A(H5N5) virus from the first human case using the ferret model. J Virol, 2026 Aug 11:e0085626. [reference]
A lethal human H5N5 influenza virus isolate exhibits low pandemic risk traits. BioRxiv, 2026 Jul 22:2026.07.20.739507. [reference] Preprint
Protective effect of A(H5N8) stockpiled vaccine against a virus genetically identical to a human isolate of bovine A(H5N1) influenza virus. EBioMedicine, 131:106430, [reference]
Genomic characterization of H6N1 avian influenza viruses from wild birds and domestic ducks in the republic of Korea and Mongolia (2022-2024). Arch Virol, 171(8):238. [reference]
Neutralizing and protective monoclonal antibodies identify antigenic sites in influenza H7 hemagglutinin and select for amino acid substitutions rarely observed at the global level. Microbiol Spectr, 2026 Aug 6:e0109126. [reference]
Impact of prior low-pathogenicity avian influenza H7N7 exposure on susceptibility and protection against homologous high-pathogenicity avian influenza H7N7 challenge in chickens. Virology, 2026 Aug 7;624:111047. [reference]
Interfering with innate immunity: type I IFNs and avian influenza susceptibility. EBioMedicine, 131:106414. [reference]
Identification and functional characterization of a novel antiviral chicken interferon-υ. Vet Microbiol, 321:111175. [reference]
Defining the molecular interaction between influenza hemagglutinin and MHC-II. bioRxiv, 2026 Jul 22:2026.07.17.738765. [reference] Preprint
Genetic diversity of H9N2 avian influenza viruses in Iran over the past two decades. Vet Res Forum, 17(3):207-216. [reference]
Genetic characterization and zoonotic potential of G1-Lineage H9N2 avian influenza viruses isolated from poultry in Pakistan, 2023. Avian Pathol, 2026 Aug 7:1-12. [reference]
Genetic evolution, phylodynamics, geographic spread of H9N2 avian influenza viruses in China from 2014 to 2025: an increasing potential zoonotic risk. Emerg Microbes Infect, 2026 Aug 3:2713320. [reference]
Epidemiological and clinical characterization of human infections with H9N2 avian influenza virus in Changsha city, China, 2015-2025. J Public Health Res, 15(3):22799036261470475. [reference]
A cross-sectional study of avian influenza virus in poultry markets of Guangdong China, 2025. Front Cell Infect Microbiol, 16:1914072. [reference]
Novel Reassortant H9N2 Avian Influenza Viruses with Dual Receptor-Binding Capacity and Evidence of Direct Mammalian Infectivity Circulating in Northeast China Live Poultry Markets. Viruses, 18(7):771. [reference]
D347G in PA is critical for the pathogenicity of H9N2 avian influenza A virus in mice. Virulence, 17(1):2711518. [reference]
Assay
Development of a multi-species luciferase-based double-antigen ELISA for the detection of antibodies against influenza A virus H5 clade 2.3.4.4b. J Clin Microbiol, 2026 Aug 13:e0190725. [reference]
Optimization of filters and processing conditions for aerosol detection of relevant avian respiratory viruses in poultry under experimental and field conditions. Vet Microbiol, 321:111159. [reference]
Monitoring of antimicrobial resistance genes and influenza viruses in avian-populated water bodies. Sustain Microbiol, 2(2):qvaf013. [reference]
Assessment
Evaluating transient risk factors for avian influenza outbreaks in Canada using case-crossover study and machine learning. Poult Sci, 105(11):107364. [reference]
A cohort study of persons exposed to highly pathogenic avian influenza A(H5N1) at premises with infected animals, England, 2023 to 2025. Euro Surveill, 31(31). [reference]
The complexity of protecting poultry from HPAIV: Findings from a case-control study in Sweden. Prev Vet Med, 256:106985. [reference]
Avian influenza risk mapping in India using machine learning. Front Vet Sci, 13:1842591. [reference]
Overview
Avian influenza and One Health: bridging animal and human health through integrated surveillance and vaccination. Front Cell Infect Microbiol, 16:1659738. [reference]
America
Asia
North Africa and Middle East
Sub-Saharan Africa
Figure 1. Number of countries reported HPAI since 1 October 2025 by subtype (left) and by region (right) as of 20 August 2026

Source: WOAH WAHIS portal, government and publications.
Table 2. Epidemiological overview for avian influenza viruses viruses known to have caused zoonotic infections in the past 20 years
Subtype | Epidemiological situation overview |
|---|---|
H5Nx Gs/GD HPAI (1996) | High pathogenicity avian influenza viruses (HPAIVs) of the H5N1 subtype were detected in geese in Guangdong Province, China in 1996. Viruses related to but not directly descended from A/Goose/Guangdong/1/96 (Gs/GD), the virus identified in China at the time have persisted, as high pathogenicity viruses Gs/GD-related HPAIVs have caused outbreaks in poultry across all regions globally other than Oceania. The initial viruses in this lineage were of the A(H5N1) subtype but other subtypes (including H5N2, H5N3 H5N5, H5N6, H5N8) have emerged, mainly in the past 10 years, as a result of reassortment with other avian influenza viruses. The common feature of these viruses is an HA gene related back to the original Gs/GD/96 virus. The HA gene of these viruses has evolved over the past 28 years, initially into 10 clades (clade 0 to 9) of which descendents of clade 2 viruses are the only ones that continue to circulate. Multiple 5th order clades persist such as the one that is currently dominant globally – clade 2.3.4.4b - whereas others have emerged and disappeared. Multiple genotypes carrying different combinations of the eight influenza A segmented genes have emerged in Gs/GD-related viruses, as a result of co-infection of birds with different avian influenza viruses that facilitated reassortment. Of considerable significance in the past has been reassortment with enzootic A(H9N2) viruses. Eurasian lineage clade 2.3.4.4b viruses formed multiple genotypes and those that crossed to North America have reassorted with North American wild bird avian influenza viruses to produced additional genotypes. Two separate systems for naming genotypes of clade 2.3.4.4b have been developed for Eurasian and North American viruses (Fusaro, et al., 2024, Youk, et al., 2023). The clade 2.3.4.4b A(H5N1) viruses detected in dairy cattle in North America in 2024 fell initially within genotype B3.13 [link] and more recently genotype D1.1 [link] using the North American naming system. Some Gs/GD-related viruses have produced severe zoonotic infections in humans, first identified in 1997 when an A(H5N1) clade 0 virus in Hong Kong SAR, China caused disease outbreaks in poultry in farms and markets as well as severe disease in humans. In several cases there was some evidence of limited onward transmission in humans and this event raised concerns that it might be the beginning of a human influenza pandemic. Despite the successful efforts to eradicate this particular strain, other Gs/GD-related viruses persisted and evolved in China, becoming more adept at infecting domestic ducks. By 2003 spread of these viruses via wild birds and live bird trade occurred across East and Southeast Asia, resulting in additional zoonotic infection in humans [link]. The important role of wild birds in the transmission of these viruses over long distances became apparent in 2005 when Gs/GD-related HPAIVs (clade 2.2) spread, primarily via wild birds, across Eurasia, and parts of Africa from western China. Most high-income countries eliminated this virus from poultry, but it persisted in several low and middle- income countries. Gs/GD-related viruses continued to evolve and spread. Additional intercontinental waves of transmission have occurred with the two most significant being those in 2014 (clade 2.3.4.4c) and from 2016 onwards (clade 2.3.4.4b). The clade 2.3.4.4b wave commenced in Asia and spread to Europe and Africa. In 2020, that also resulted in spread of these viruses to North America (2014-15 and 2021-22), with the latest outbreak extending through central and South America and to sub-Antarctic islands. In 2022/2023, H5N1 2.3.4.4b caused extensive infection in coastal seabirds and mass die-offs of numerous ecologically important wild bird species. . In 2026, H5N1 clade 2.3.4.4b virus reached Australia and New Zealand, with evidence suggesting introduction through migratory wild birds originating from sub‑Antarctic/Antarctic zones. Since 2024, H5N1 2.3.4.4b caused infection in goats (1 farm), alpaca (1 backyard farm), swine (1 farm) and dairy cattle (1 173 farms in 20 states, as of 26 August 2026) in the United States of America, see HERE. In 2025, H5N1 2.3.4.4b caused infection in sheep in the United Kingdom, see HERE; and H5 antibodies were also found in sheep in Norway. [link1, link2] Clade 2.3.4.4b A (H5N1) viruses have caused few human cases but have resulted in multiple mammalian cases including aquatic mammals. For an updated list of bird and mammalian species affected with A(H5Nx) see HERE. Among the other Gs/GD-related virus clades that remain endemic in specific areas are clade 2.3.2.1a H5N1 viruses that have persisted in South Asia since 2010 and rarely associated with disease in humans. Clade 2.3.2.1g viruses have been present in Indonesia since 2012 and clade 2.3.2.1c/e viruses are still circulating in Cambodia, Viet Nam and Lao People’s Democratic Republic. A novel reassortant influenza A(H5N1) virus has been detected in poultry in Cambodia (since 2023), Lao People's Democratic Republic and Viet Nam (since 2022) and was also detected in the human cases reported from Cambodia since late 2023 and Viet Nam in 2024. This virus contains the surface proteins from clade 2.3.2.1c that has circulated locally, but internal genes from a more recent clade 2.3.4.4b virus. [link] For an updated list of confirmed human cases with A(H5N1) see HERE and HERE. In addition, since the first human case of A(H5N6) was reported in Sichuan, China in 2014, 94 human cases have been associated with clade 2.3.4.4b and 2.3.4.4h A(H5N6) viruses with most of these occurring in 2021 and 2022 [link]. The first human cases (asymptomatic) of A(H5N8) were reported in Astrakhan Oblast, Russian Federation [link] in adults who engaged in depopulation on a layer farm due to H5N8 HPAI in December 2020 [link]. The influenza A(H5N8) viruses isolated from this poultry outbreak in Astrakhan belonged to clade 2.3.4.4b [GISAID EPI_ISL_1038924]; the first human case (fatal) of A(H5N5) was reported in November 2025 in the United States of America with reported exposure to poultry. [link] |
| Avian origin H3N8 LPAI | An Influenza A(H3N8) virus lineage emerged in live bird markets in southern China in mid-2021. Since then, three human cases of Influenza A(H3N8) have been reported: In April 2022, the first human clinical case associated with this lineage was reported in Henan Province, China and was associated with severe disease [link]. In May 2022, a 5-year-old boy was diagnosed with a mild influenza A(H3N8) infection in Changsha City, Hunan Province, China. On 27 March 2023, a third human case was reported from Guangdong Province, China in a 56-year-old female with underlying illness who subsequently died. One of the A(H3N8) viruses isolated from a human was found to be transmissible by air in ferrets [link] but no evidence of sustained human transmission has been reported. |
H5N5 HPAI (2025) | One human case in China with reported exposure to poultry. [link] |
H7N4 LPAI (2017) | The first human case (fatal) was reported in November 2025 in the United States of America with reported exposure to poultry. [link] |
H7N7 LPAI | One human case of H7N7 was reported in a duck farmer in Taiwan Province of China. More than 90 cases have been reported since 1959, mostly mild with one fatal case. [link] |
H7N9 LPAI (2013) & HPAI (2017) | Reported only in China with over 1 000 human cases between 2013 and 2017 with a marked increase in 2017 compared to previous waves. Most human cases exposed in live bird markets. Nation-wide vaccination campaign in poultry since Sep 2017: Last reported human case in 2019 [link]. See FAO H7N9 situation update Figure 5. |
| H9N2 LPAI | First human case reported in 1998. To date, 180 influenza A(H9N2) human cases diagnosed worldwide, many of them were reported from China since December 2015. Most cases mild and involving children. Only two fatal cases reported. [link] Endemic in multiple countries in Africa and Asia, a cause of significant production losses and mortalities in poultry production systems. Three major lineages and multiple genotypes. |
| H10Nx LPAI | To date, seven influenza A(H10N3) human infections have been reported globally [link]. In May 2021, the first case in Jiangsu Province, China [link], then in Zhejiang (2022), Yunnan and Guangxi (2024) and Shaanxi and Guangdong (2025) provinces in China. The first influenza A(H10N5) human infection was reported in Zhejiang Province, China [link]. Since 2013, three influenza A(H10N8) human infections have been reported in Jiangxi Province, China. [link] |
For high-level, the recommendations from the FAO Global Dialogue - Tackling high pathogenicity avian influenza together provide a clear framework for coordinated science-based actions on Early detection, Rapid response, Biosecurity, Vaccination, Business and trade dimensions, One Health and systems-based approaches, Public-private partnerships...
For grass root level. the practical recommendations for day-to-day activities are suggested below to mitigate risk and reduce impact of HPAI...
General recommendations
It is important to report sick or dead birds – both wild birds and poultry - or wild mammals to local authorities (veterinary services, public health officials, community leaders etc.). These should be tested for avian
influenza viruses...
Recommendations to poultry producers
Farmers and poultry producers should step up their biosecurity measures in order to prevent potential virus introduction from wild birds or their faeces...
Recommendations to hunters
Hunting associations and wildlife authorities should be aware that avian influenza viruses might be present in waterfowl and some other species hunted and that hunting, handling and dressing of shot game carries the risk
of spreading avian influenza viruses to susceptible poultry...
Recommendations to national authorities
Increase surveillance efforts for the early detection of influenza viruses in poultry and dead wild species including certain mammals...
For full recommendations including non-avian species please see [link].
Note: many publication links have been moved into ‘More important links’ below.
Next issue: 24 Sept. 2026
Information provided herein is current as of the date of issue. Information added or changed since the last Global AIV with Zoonotic Potential situation update appears in orange. Human cases are depicted in the geographic location of their report. For some cases, exposure may have occurred in one geographic location but reported in another. For cases with unknown onset date, reporting date was used instead. FAO compiles information drawn from multiple national (Ministries of Agriculture or Livestock, Ministries of Health, Provincial Government websites; Centers for Disease Prevention and Control [CDC]) and international sources (World Health Organization [WHO], World Organisation for Animal Health [WOAH]), as well as peer reviewed scientific articles. FAO makes every effort to ensure, but does not guarantee, accuracy, completeness or authenticity of the information. The boundaries and names shown and the designations used on these map(s) do not imply the expression of any opinion whatsoever on the part of FAO concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers and boundaries. Dashed lines on maps represent approximate border lines for which there may not yet be full agreement.
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